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OS-01 LIP Duo

The only 24-hour system powered by the OS-01 Peptide™ to shield and restore your lips at the cellular level01.



  • OS-01 LIP SPF protects against UV and cellular aging by day

  • OS-01 LIP Mask promotes collagen, elastin, and hyaluronic acid at night


  • Dermatologist tested, fragrance-free, safe for sensitive skin


  • Exclusive early access to new products
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OS-01 LIP SPF

Daytime:

Gently squeeze a small amount of OS-01 LIP SPF onto the applicator tip and apply a thin layer directly to lips prior to sun exposure.

OS-01 LIP Mask

Nighttime:

Using the metal applicator, apply a generous layer of OS-01 LIP Mask onto clean, dry lips before bed and leave on overnight.

*Applies clear. Due to natural ingredients, color in compact may vary slightly.

HOW OS-01 WORKS

The science to unlock your healthiest skin

Backed by over a decade of longevity research, the OS-01 Peptide™ targets the cells that speed up the visible signs of aging.02

OS-01 is scientifically proven to:

  • Support repair by reducing the buildup of senescent “zombie” cells
  • Improve how skin behaves, stimulating collagen and hyaluronic acid production
  • Build resilience, keeping your skin healthy and youthful as you age

Full ingredient list

OS-01 LIP SPF ingredients

Active ingredients: Zinc Oxide 5.5%

Inactive Ingredients: Simmondsia, Chinensis (Jojoba) Seed Oil, Ethylene/Propylene/Styrene Copolymer, Ethylhexyl Palmitate, Butyloctyl Salicylate, Caprylic/Capric Triglyceride, Water (Aqua), Garcinia Indica Seed Butter, Tocopheryl Acetate, Butylene/Ethylene/Styrene Copolymer, Glyceryl Oleate, Glyceryl Dioleate, Glycerin, Oleic Acid, Tribehenin, Sorbitan Isostearate, Palmitoyl Tripeptide-1, Dipalmitoyl Hydroxyproline, Trihydroxystearin, Sodium Hyaluronate, Glucomannan, Tetrahexyldecyl Ascorbate, Bisabolol, Decapeptide-52*, Ethylhexylglycerin, Caprylyl/Capryl Glucoside, Propanediol, Ectoin, Centella Asiatica Extract, Hippophae Rhamnoides Oil, Helianthus Annuus (Sunflower) Seed Oil, Copernicia Cerifera (Carnauba) Wax, Tocopherol, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate, Polyhydroxystearic Acid, Polyglyceryl-3 Polyricinoleate, Isostearic acid, Lecithin, Beta-Sitosterol, Squalene, Lactic Acid, Palmitic acid. *OS-01 Peptide™

OS-01 LIP ingredients

Bis-Diglyceryl Polyacyladipate-2, Hydrogenated Polyisobutene, Diisostearyl Malate, Phytosteryl/Isostearyl/Cetyl/Stearyl/Behenyl Dimer Dilinoleate, Water (Aqua), Polyglyceryl-2 Diisostearate, Hydroxystearic Acid, Butyrospermum Parkii (Shea) Nut Extract, Squalane, 1,2-Hexanediol, Glycerin, Glyceryl Oleate, Cucumis Sativus (Cucumber) Seed Oil, Pentaerythrityl Tetraisostearate, Cetearyl Alcohol, Glyceryl Dioleate, Simmondsia Chinensis (Jojoba) Seed Oil, Euphorbia Cerifera (Candelilla) Wax, Helianthus Annuus (Sunflower) Seed Wax, Ethylhexylglycerin, Ethylhexyl Palmitate, Citrullus Lanatus (Watermelon) Fruit Extract, Panthenol, Lens Esculenta (Lentil) Fruit Extract, C10-18 Triglycerides, Tocopherol, Bisabolol, Punica Granatum Flower Extract, Pyrus Malus (Apple) Fruit Extract, Sodium Hyaluronate, Ceramide NP, Polyglyceryl-3 Diisostearate, Propanediol, Triolein, Caprylic/Capric Triglyceride, Sodium Lactate, Tamarindus Indica Seed Polysaccharide, Sodium Benzoate, Sodium PCA, Phaeodactylum Tricornutum Extract, Haematococcus Pluvialis Extract, Trihydroxystearin, Lecithin, Potassium Sorbate, Stearalkonium Hectorite, Propylene Carbonate, Allantoin, Olea Europaea (Olive) Fruit Oil, Pantolactone, Decapeptide-52*, Oleic Acid, Palmitoyl Hexapeptide-12, Glucomannan. *OS-01 Peptide™

OS-01 LIP Duo

5.0
Rated 5.0 out of 5 stars
Based on 20 reviews
Total 5 star reviews: 20 Total 4 star reviews: 0 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 0
100%would recommend this product
20 reviews
  • DG
    Donna G.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    19 seconds ago
    LIP Duo

    This is the best lip treatment I have used in my 73 years on earth. I put it on once at night and once in the morning and my lips are soft ALL DAY LONG and when I wake up in the morning. No more chapped lips EVER!!! Amazing. The SPF is fantastic also and so easy to keep in my purse. I will be giving this Duo to my daughters and daughter-in-law as a stocking stuffer this Christmas!

  • JC
    Jacqueline C.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    12 hours ago
    Best lip products I’ve ever used!!!

    I have tried everything to keep my lips from drying and cracking. Problem solved! I especially love the lip mask. Put it on just before bedtime. My lips look plump and moisturized at 55.

  • MM
    Maya M.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    13 hours ago
    Lip duo

    Love the lip mask. Noticed an immediate improvement in my lips overall moisture. I typically have dry lips and they already look fuller, plumper and the moisture lasts throughout the day when I apply it at night. Love the product so far!

  • NM
    na M. '. P.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    14 hours ago
    Self-Care TREAT!!!!!!!!!!!!!

    I had been using the Lip SPF since it was first introduced a few months ago. The luxurious balm lasts much longer than other similar products. The silky sheen is lightweight yet effective. PLUS the added benefit of the Peptide seems to have improved the texture of my lips.

    And now the Lip Masque…..WOW!!!!!!!!!!!!!!!!!!!!!!

    In one week the lines around my lips are smoothing out and my lips look healthier.

    HYPE or Real????

    I am a HUGE fan of OS-01 products. Since this past May I have been slowly incorporating each product into my daily regime to be able to observe progress… or not.

    This is the REAL deal!

    OS-01 indeed!!!!!!!!!

    Self-Care TREAT!!!!!!!!!!!

  • LC
    LIANA C.
    Verified Buyer
    Reviewing
    OS-01 LIP Duo
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Love them both

    I actually have yet to find a One Skim product that I haven't loved but I was excited to try the Lip Duo as grinding a good Lip product is not easy. This does not disappoint and it's perfect for the upcoming season when my lips are always dry.

    I do find this to really keep my lips moist and hydrated and although it hasn't been more than a few days I am excited to see if it will also decrease the fine lines I have around my mouth. I'm deathly afraid of getting lip fillers as I've seen some bad and obvious over done plumping.

    Right now after just a day of use I can daily my lips stay moist and that alone is better than anything I have tried before.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims.
02 Zonari, A.,et al.Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models.npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1