OS-01 FACE MOISTURIZER
50 mL / 1.7 fl oz
Smooth and firm skin with our daily moisturizer for the face and neck, powered by the OS-01 Peptide™.01
- Boosts hydration, elasticity, and barrier function
- 96% showed an improvement in firmness and radiance
- Dermatologist tested, fragrance-free, safe for sensitive skin
- Exclusive early access to new products
- Earn 2x points on all recurring orders
- Easily change, skip or cancel anytime
LIMITED TIME OFFER
Travel-size OS-01 EYE with your first subscription
Free shipping on orders over
Try it risk-free for 30 days!
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Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin to retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.
"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
96
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Blocking Peptide™
The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE MOISTURIZER
- GCGabrielle C.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars3 minutes agoWorks great
This works great. I'm on the prevention route rather than reversal route so I can't speak to that. Seems to help.
- CRChante R.Verified ReviewerReviewingOS-01 FACE MOISTURIZERI recommend this productRated 5 out of 5 stars4 days agoBest Facial Rejuvenation EVER
I stopped retinol entirely and have never been happier. My skin health has reversed and my under eye bags have been conquered! I look younger than I had in years before starting One Skin. Thank you! It is truly great for my skin health.
OneSkin4 days agoHi Chante! Thank you so much for your incredible 5-star feedback about OS-01 FACE! We're absolutely thrilled to hear that you consider it the best facial rejuvenation ever and that you're experiencing such amazing transformative results - that kind of enthusiastic response really means the world to all of us at OneSkin!
It's wonderful that you've found such success moving away from retinol and discovering how OS-01 FACE works for your skin! The fact that you're seeing your skin health reverse, conquering those under eye bags, and looking younger than you have in years shows exactly how our science-backed OS-01 peptide works at the cellular level to target senescence and support your skin's natural renewal processes in a gentler yet powerful way.
Your experience demonstrates the beauty of finding the right approach for your individual skin - sometimes stepping away from traditional actives like retinol and embracing innovative peptide technology can create exactly the kind of dramatic improvements you're describing. The visible age-reversing results you're seeing are exactly what we hoped you'd experience with consistent use!
Thank you for taking the time to share such encouraging feedback about your OS-01 FACE experience - your 5-star review and enthusiasm about looking younger truly means so much to us!
- MSMarcela S.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars5 days agoGentle and moisturizing
I love that it’s absorbs quickly, it doesn’t have a strong scent, gentle enough on the skin to work with retinoids. Great product!
- NNathalieReviewingOS-01 FACE Refill PouchRated 3 out of 5 stars5 days ago3 Stars
I do not know if this product works. It is very light and disappears so I need a moisturizer on top. It can also pill with other serums. Finally the dispenser always stops working and I have to dispense outside of the plastic case.
- SKSuzee K. M.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars5 days agoMy Face Loves This!
I’ve really enjoyed using the OS-01 FACE moisturizer, so the refill pouch is a no-brainer for me; easy to replace and no extra bottles being tossed! The formula feels lightweight but still gives my skin the hydration it needs without feeling heavy or greasy. My skin feels softer, smoother, and overall just looks healthier and more refreshed. I also appreciate that a little goes a long way. Great product, smart refill option, and definitely something I’ll continue using!
