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OS-01 HAIR SCALP SERUM

4.4
4.4 out of 5
4.4 (247)
The first daily scalp serum powered by the OS-01 PeptideTM to help support fuller, thicker-looking hair with age and stress.



  • Nourishes the scalp, and promotes visibly thicker, fuller, denser hair01

  • 81% showed a +40% improvement in visible hair density after 6 months01

  • Dermatologist tested, fragrance-free, suitable for sensitive skin


Disclaimer: Dermaroller is for cosmetic use only. Not intended to diagnose, treat, cure, or prevent any disease.
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1 month supply delivered every 1 month.

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3 month supply delivered every 3 months.

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6 month supply delivered every 6 months.

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OS-01 HAIR Dermaroller

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BENEFITS

Daily scalp serum designed to nourish the scalp and support visibly healthier and younger-looking hair.

Promote hair longevity

Addresses visible hair changes associated with age and stress.

Hair health starts at the scalp

Suitable for sensitive skin and supports a healthy scalp microbiome to support healthy hair.

Support thicker, denser, fuller-looking hair

Key ingredients complement the OS-01 Peptide to promote strong, healthy-looking hair for progressive improvements in visible density and thickness.

CLINICAL DATA

Visible results, scientifically validated

81
of participants showed an increase in visible hair density (average +40%) after 6 months 01

78
of participants showed an increase in hair visible thickness (average +43%) after 6 months01

81
 of participants observed overall improvements in their hair after 3 months 01

78
of participants said the overall health of their hair improved after 6 months 01

5-STAR REVIEWS

See why customers love OS-01 HAIR

"Just fantastic growth in areas where I desperately needed it." — LaDonna L., Beta Tester

"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester

"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester

What makes OS-01 HAIR unique?

  • Proprietary ingredient
  • No harsh side effects
  • Lightweight & non-greasy
  • Drug-free
  • No prescription
  • Supports scalp health
    • OS-01 HAIR

    • Prescription Hair Treatments

    • X
    • X
    • X
    • X
    • X
    • Leading Supplement

    • X
    • N/A
    • X
    • Leading Hair Serum

    • X
    • Invasive Treatments (PRP, hair transplant, etc.)

    • X
    • X
    • N/A
    • N/A
    • DIY Oils

    • X
    • X

How to Apply OS-01 HAIR

  1. We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
  2. Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose.  Apply the serum directly to your scalp, starting at your natural part or hairline.
  3. Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
  4. Massage the serum into your scalp with your fingertips to ensure even distribution.
  5. Do not rinse. Style as usual.
  6. Use daily on dry or damp hair.

A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.

Your OS-01 HAIR questions answered

HOW IT WORKS

Powered by the OS-01 Senescence Blocking Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin, scalp, and hair aging, for skin and hair that looks and feels younger and healthier over time.02

All Ingredients

Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.

OS-01 HAIR SCALP SERUM

4.4
Rated 4.4 out of 5 stars
Based on 247 reviews
Total 5 star reviews: 166 Total 4 star reviews: 45 Total 3 star reviews: 22 Total 2 star reviews: 6 Total 1 star reviews: 8
85%would recommend these products
247 reviews
  • AP
    Alison P.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    New hair growth

    Definitely seen some new baby hair growth in the treated area! Been using for 3+ months now and am gonna keep religiously using it till end of my bottles!

  • K
    Kathryn
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 4 out of 5 stars
    1 week ago
    4 Stars

    So car so good. I dimt yhink ive been using it long enough to reach full benefit. I will keep using ti see if my hair starts to come in thicker.

  • LC
    Linda C.
    Verified Buyer
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Nice product to enhance volume of hair

    My husband can see a difference in hair volume after just 2 short months. We are excited to see what happens after the 3-6 month mark.

  • CD
    Christine D.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 4 out of 5 stars
    1 week ago
    So far So good

    Ive been using for about a month. It's too early to see hair growth but it has helped my scalp health. Unfortunately, as my hair thinned, the areas it thinned became sore/sensitive and itchy/dry. My dermatologist basically said nothing was wrong expect for minor dandruff. the only product that helped was an oil that made my hair look greasy. 2 weeks on oneskin applying 2X a day and my scalp has been relieved from itchy soreness. That leads me to believe that its helping create a less inflamed / irritated environment neeeded for hair growth. I will re-review in 3 months

    OneSkin
    1 week ago

    Hi Christine! Thank you so much for your wonderful 4-star feedback about OS-01 HAIR SCALP SERUM! We're absolutely thrilled to hear that you're experiencing such positive results with your scalp health after just two weeks of consistent use - that kind of relief from itchy soreness really means the world to all of us at OneSkin!

    Your insights about creating a less inflamed environment for hair growth show exactly the kind of thoughtful understanding of how our science-backed approach works to support your scalp's natural healing processes. We're so glad that OS-01 HAIR has been able to provide the scalp comfort that other products couldn't achieve without the greasy residue!

    We completely understand your realistic perspective about the timeline for visible hair growth - one month is still early in the process, and your plan to reassess at three months shows exactly the kind of patience and commitment that leads to the best results. The fact that you're already seeing such encouraging improvements in scalp health and comfort is a wonderful foundation for the hair growth journey ahead.

    Your experience with thinning-related scalp sensitivity is something many of our customers can relate to, and we really appreciate you sharing how OS-01 HAIR has helped address those specific concerns that even your dermatologist couldn't fully resolve.

    Thank you for taking the time to share such detailed and encouraging feedback about your OS-01 HAIR experience - we'd love to hear how you get on at the three-month mark, and your 4-star review truly means so much to us!

  • CF
    Camilla F.
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    3 weeks ago
    THE only thing that has worked for me

    I’ve tried it all (well, that’s not true. I’m not willing to take use/Monoxonil), so better said, I’ve tried all the natural options out there, and this is the only product that actually filled in my menopause-fading hair line. My fine hair does go flat on the days I don’t hair wash, but it’s worth it to actually have hair!

    OneSkin
    2 weeks ago

    Hi Camilla!

    Thank you so much for taking the time to share your incredible experience with the OS-01 HAIR SCALP SERUM and for the fantastic 5-star rating! We're absolutely thrilled to hear that after trying so many natural options, OneSkin is THE product that actually delivered real results for your menopause-related hair changes — that means everything to us and shows that the OS-01 peptide is working its magic at the cellular level to support your scalp health.

    We completely understand your approach to wanting natural solutions and avoiding certain treatments — it's exactly why we've worked so hard to create effective formulations that work with your body's natural processes. Hearing that our serum actually filled in your fading hairline is such incredible feedback and exactly the kind of results we hope to achieve for our customers.

    We also totally get the trade-off with fine hair feeling a bit flat on non-wash days when you're using the serum consistently. You're absolutely right that having actual hair growth is worth those minor styling adjustments! Many customers with fine hair find that the benefits of consistent use far outweigh those temporary texture changes, and it sounds like you've found that perfect balance in your routine.

    Your experience is so valuable for other women going through similar changes — knowing that there's a natural option that actually works can make such a difference for someone who's tried everything else without success.

    Thank you for choosing OneSkin and for being so honest about both the amazing results and the realistic day-to-day experience, Camilla — we're so glad you finally found something that works!

Citations

01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

More Scientific Resources

Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259

Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318

Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269 

Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/

Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic 

Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext 

Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/ 

Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/