OS-01 HAIR SCALP SERUM
OS-01 HAIR SCALP SERUM
Reduce shedding and reactivate the hair growth cycle with our daily scalp serum, powered by the OS-01 Peptide™.01
- Nourishes the scalp, and promotes thicker, fuller, denser hair
- 81% showed a +40% improvement in hair density after 6 months
- Dermatologist tested, fragrance-free, safe for sensitive skin
1 month supply delivered every 1 month.
3 month supply delivered every 3 months.
6 month supply delivered every 6 months.
include dermaroller?
Teal Travel Bag + OS-01 EYE Travel Size with your first subscription
SUBSCRIPTION EXCLUSIVES
- Plastic neutral refillable packaging
- Exclusive early access to new products
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BENEFITS
Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01
Prevent a root cause of hair thinning
Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09
Scalp health
Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09
Thicker, denser, fuller hair
Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01
CLINICAL DATA
Visible results, scientifically validated
81
of participants showed an increase in hair density (average +40%) after 6 months 01
78
participants showed an increase in hair thickness (average +43%) after 6 months 01
81
of participants observed overall improvements in their hair after 3 months 01
78
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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Prescription Hair Treatments
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Leading Supplement
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- N/A
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Leading Hair Serum
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Invasive Treatments (PRP, hair transplant, etc.)
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DIY Oils
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The science behind OS-01 HAIR
The science behind OS-01 HAIR
Your scalp ages just like the rest of your skin. But instead of lines and wrinkles, the accumulation of senescent cells impairs how your hair follicles function, leading to thinner, weaker strands over time.03-05
OS-01 HAIR was developed to target this issue at the root. It’s the first and only scalp serum powered by the OS-01 peptide, scientifically proven to reduce cellular senescence—a key driver of age-related hair thinning.02,09
When tested on senescence-induced cells in the lab, OS-01 HAIR significantly reduced senescence, reinforcing OS-01 HAIR’s potential to address one of the core biological processes behind age-related thinning and hair loss.03-09
Just like healthy skin supports better texture and tone, a healthier scalp sets the stage for stronger, fuller hair.
6 active ingredients complement the OS-01 peptide
How to Apply OS-01 HAIR
- We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
- Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose. Apply the serum directly to your scalp, starting at your natural part or hairline.
- Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
- Massage the serum into your scalp with your fingertips to ensure even distribution.
- Do not rinse. Style as usual.
- Use daily on dry or damp hair.
A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR SCALP SERUM
- MMorganVerified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars4 minutes agoTBD!
Been using this for about a month but I agree with other reviews - very light and non greasy. Yay
- ESEllen S.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars4 days agoEasy to Use
This serum is not greasy at all, like some others I’ve tried. Too soon to tell if it’s thickening my hair or helping with growth, but five stars for ease of use and texture. I really like the fact that it’s not oily or greasy!
- SSueVerified BuyerReviewingOS-01 HAIR SCALP SERUMRated 3 out of 5 stars4 days agoTook away my curls
The OS-1 hair serum might help with hair growth but it flattened out my curls. It’s not something I can use daily because of this result.
OneSkin3 days agoHi Sue!
We're sorry to hear that the OS-01 HAIR SCALP SERUM affected your curl pattern!
Everyone's hair responds differently to new products, and we understand how important it is to maintain your natural curl texture while working on hair growth goals. Curl patterns can be sensitive to certain formulations. Some customers with curls prefer using a lighter amount or limiting application to the scalp only to avoid affecting texture.
Your experience is really valuable feedback for us and helps other customers with similar hair types understand how the product might work for them.
We really appreciate you taking the time to share your honest review - it helps us better understand how our products interact with different hair textures and styling needs!
- LRLynn R.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars4 days agoOnly Your Hair Dresser Knows….
I’m a long time user of the One Skin Face line and swear by it. When they released the hair line i thought it would be good to try as my hair was noticeably getting thinner in my mid 70’s. I didn’t expect much so was surprised when my hairdresser commented on all the new growth. Frankly I had forgotten about it. I just compared photos I took on April 20, 2025 to Jan 11, 2026 and even i can see the difference. I didn’t even use the product daily as instructed but more as part of my shampoo/conditioner routine every 2nd or 3rd day. Kudos to One Skin for another awesome product!
OneSkin3 days agoThank you so much for your incredible feedback, Lynn! We are absolutely thrilled to hear that you're experiencing such amazing results with the OS-01 HAIR SCALP SERUM!
What an incredible testament to the effectiveness of our science-backed formula that your hairdresser noticed the new growth before you even realized it yourself! We're so excited that you can see the difference in your photos; those visual results are truly wonderful to hear about.
We're so grateful that it has helped with your hair thickness concerns and delivered results that exceeded your expectations.
Your recommendation means the world to us, and we truly appreciate you taking the time to share your amazing experience with us!
- CcryssyVerified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars1 week agoloving it
Ok, first thing is i love how weightless this is. It takes a bit of time to absorb in my scalp but it doesn't leave any greasiness and I love the smell of it! I have had significant hair loss. Only been using for about2 months so will update in a few more months but so far I am loving it. hair loss has slowed down a lot. I know hair loss i more about stress and lifestyle but I still need all the extra help i can get espeically with the thinning my hair loss has came with.
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/
12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).