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OS-01 HAIR SCALP SERUM

4.4
4.4 out of 5
4.4 (221)

OS-01 HAIR SCALP SERUM

Topical Supplement

4.4
4.4 out of 5
4.4 (221)
The first daily scalp serum powered by the OS-01 PeptideTM to help support fuller, thicker-looking hair with age and stress.



  • Nourishes the scalp, and promotes visibly thicker, fuller, denser hair01

  • 81% showed a +40% improvement in visible hair density after 6 months01

  • Dermatologist tested, fragrance-free, suitable for sensitive skin


Disclaimer: Dermaroller is for cosmetic use only. Not intended to diagnose, treat, cure, or prevent any disease.
SAVE 10% EVERY ORDER
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1 month supply delivered every 1 month.

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3 month supply delivered every 3 months.

SAVE 25% EVERY ORDER
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6 month supply delivered every 6 months.

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OS-01 HAIR Dermaroller

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BENEFITS

Daily scalp serum designed to nourish the scalp and support visibly healthier and younger-looking hair.

Promote hair longevity

Addresses visible hair changes associated with age and stress.

Hair health starts at the scalp

Suitable for sensitive skin and supports a healthy scalp microbiome to support healthy hair.

Support thicker, denser, fuller-looking hair

Key ingredients complement the OS-01 Peptide to promote strong, healthy-looking hair for progressive improvements in visible density and thickness.

CLINICAL DATA

Visible results, scientifically validated

81
of participants showed an increase in visible hair density (average +40%) after 6 months 01

78
of participants showed an increase in hair visible thickness (average +43%) after 6 months01

81
 of participants observed overall improvements in their hair after 3 months 01

78
of participants said the overall health of their hair improved after 6 months 01

5-STAR REVIEWS

See why customers love OS-01 HAIR

"Just fantastic growth in areas where I desperately needed it." — LaDonna L., Beta Tester

"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester

"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester

What makes OS-01 HAIR unique?

  • Proprietary ingredient
  • No harsh side effects
  • Lightweight & non-greasy
  • Drug-free
  • No prescription
  • Supports scalp health
    • OS-01 HAIR

    • Prescription Hair Treatments

    • X
    • X
    • X
    • X
    • X
    • Leading Supplement

    • X
    • N/A
    • X
    • Leading Hair Serum

    • X
    • Invasive Treatments (PRP, hair transplant, etc.)

    • X
    • X
    • N/A
    • N/A
    • DIY Oils

    • X
    • X

How to Apply OS-01 HAIR

  1. We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
  2. Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose.  Apply the serum directly to your scalp, starting at your natural part or hairline.
  3. Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
  4. Massage the serum into your scalp with your fingertips to ensure even distribution.
  5. Do not rinse. Style as usual.
  6. Use daily on dry or damp hair.

A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.

Your OS-01 HAIR questions answered

HOW IT WORKS

Powered by the OS-01 Senescence Blocking Peptide™

Born from over a decade of longevity science, OS-01 is engineered to address a key driver of visible skin, scalp, and hair aging, for skin and hair that looks and feels younger and healthier over time.02

All Ingredients

Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.

OS-01 HAIR SCALP SERUM

4.4
Rated 4.4 out of 5 stars
Based on 221 reviews
Total 5 star reviews: 148 Total 4 star reviews: 39 Total 3 star reviews: 21 Total 2 star reviews: 6 Total 1 star reviews: 7
85%would recommend these products
221 reviews
  • LC
    Lisa C.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Skeptic now a believer

    I had tried so many products to no perminant results. So I was skeptical that this would be any better. But to my surprise it does!! It took a full 3-4 months to begin to see my hair growing back but there is no denying my bald spots are growing smaller every day!! I wish I had taken before photos. This product works!!

    OneSkin
    Yesterday

    Hi Lisa! Thank you so much for your incredible 5-star feedback about OS-01 HAIR SCALP SERUM! We're absolutely thrilled to hear that you've gone from skeptic to believer - that transformation in your experience is exactly what gets us so excited about our science-backed formulation!

    We completely understand that skepticism after trying so many products without lasting results, and we love that you gave OS-01 HAIR SCALP SERUM the full 3-4 months it needed to really show its potential! Your patience and commitment to consistent use during that initial period really shows how dedicated you were to giving it a fair chance, and we're so excited that your persistence is paying off with those visible results.

    Seeing those bald spots growing smaller every day must be such an encouraging and confidence-boosting experience! Your observation about wishing you had taken before photos really shows just how meaningful the changes have been - when results are that noticeable, it's natural to want to document that amazing progress you're seeing.

    Hair regrowth is definitely a journey that requires time and consistency, and your experience of seeing those changes begin around the 3-4 month mark aligns perfectly with how our peptide technology works to support the scalp environment and hair follicle health over time. Stories like yours about experiencing real, visible improvements after giving the formula time to work are exactly why we're so passionate about what we do!

    Thank you for taking the time to share such encouraging feedback about your transformation - your 5-star review truly means the world to all of us at OneSkin!

  • S
    Stephanie
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    5 Stars

    I love how it makes my scalp feel!!

  • J
    Jessica
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 4 out of 5 stars
    4 days ago
    So far so goo

    I am only going on my third month but I have definitely noticed a difference. Even my har dresser commented on see lots of new growth and thickness. The only complaint I have is I did buy the 6month supply and what you get doesn’t seem enough to be used daily.

    OneSkin
    Yesterday

    Hi Jessica! Thank you so much for your wonderful 4-star feedback about OS-01 HAIR SCALP SERUM! We're absolutely thrilled to hear that you're noticing such meaningful changes after just three months - and how exciting that your hairdresser is commenting on the new growth and thickness! That kind of professional observation really shows how our science-backed formulation is working to support your scalp health and hair growth.

    We love that you're experiencing those visible improvements in both growth and thickness - that's exactly what gets us so excited about how our targeted scalp serum works to create the optimal environment for healthy hair! Your progress in just three months really demonstrates how consistent use allows the formula to work on improving scalp health from the foundation up.

    We completely understand your concern about the quantity with daily use, and we really appreciate you sharing that honest feedback. Usage can vary from person to person based on scalp size and application technique, and we want to make sure you're getting the full benefit throughout your routine. A few drops applied directly to the scalp and gently massaged in typically provides the coverage needed, but we know everyone's application style is different.

    Stories like yours about seeing such encouraging results that even professionals notice while staying committed to your routine are exactly why we're so passionate about what we do! Your experience with the visible improvements in growth and thickness really shows how our scalp-focused approach is delivering those meaningful changes you're looking for.

    Thank you for taking the time to share such encouraging feedback about your experience - your 4-star review truly means the world to all of us at OneSkin!

  • KK
    K K.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    1 week ago
    Hair growth

    I have noticed hair growth in areas of hair loss.

  • JG
    james g.
    Verified Buyer
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 5 out of 5 stars
    2 weeks ago
    Seems to work!

    A few months in and my hair seems thicker.

Citations

01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

More Scientific Resources

Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259

Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318

Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269 

Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/

Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic 

Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext 

Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/ 

Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/