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Up to 25% off on your first 3 deliveries of a new subscription! Ends 1/19. Terms apply.

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OS-01 HAIR SCALP SERUM

Topical Supplement

Reduce shedding and reactivate the hair growth cycle with our daily scalp serum, powered by the OS-01 Peptide™.01



  • Nourishes the scalp, and promotes thicker, fuller, denser hair

  • 81% showed a +40% improvement in hair density after 6 months

  • Dermatologist tested, fragrance-free, safe for sensitive skin

SAVE 15%
$69.00 $58.65

1 month supply delivered every 1 month.

SAVE 20%
$207.00 $166.00

3 month supply delivered every 3 months.

SAVE 25%
$424.00 $321.00

6 month supply delivered every 6 months.

include dermaroller?

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1st SHIPMENT
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2nd SHIPMENT
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3RD SHIPMENT
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SUBSCRIPTION EXCLUSIVES

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BENEFITS

Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01

Prevent a root cause of hair thinning

Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09

Scalp health

Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09

Thicker, denser, fuller hair

Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01

CLINICAL DATA

Visible results, scientifically validated

81

of participants showed an increase in hair density (average +40%) after 6 months 01

78

participants showed an increase in hair thickness (average +43%) after 6 months 01

81

 of participants observed overall improvements in their hair after 3 months 01

78

of participants said the overall health of their hair improved after 6 months 01

5-STAR REVIEWS

See why customers love OS-01 HAIR

"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester

"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester

"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester

What makes OS-01 HAIR unique?

  • Proprietary ingredient
  • No harsh side effects
  • Lightweight & non-greasy
  • Drug-free
  • No prescription
  • Supports scalp health
    • OS-01 HAIR

    • Prescription Hair Treatments

    • X
    • X
    • X
    • X
    • X
    • Leading Supplement

    • X
    • N/A
    • X
    • Leading Hair Serum

    • X
    • Invasive Treatments (PRP, hair transplant, etc.)

    • X
    • X
    • N/A
    • N/A
    • DIY Oils

    • X
    • X
OneSkin

The science behind OS-01 HAIR

The science behind OS-01 HAIR

Your scalp ages just like the rest of your skin. But instead of lines and wrinkles, the accumulation of senescent cells impairs how your hair follicles function, leading to thinner, weaker strands over time.03-05

OS-01 HAIR was developed to target this issue at the root. It’s the first and only scalp serum powered by the OS-01 peptide, scientifically proven to reduce cellular senescence—a key driver of age-related hair thinning.02,09

When tested on senescence-induced cells in the lab, OS-01 HAIR significantly reduced senescence, reinforcing OS-01 HAIR’s potential to address one of the core biological processes behind age-related thinning and hair loss.03-09

Just like healthy skin supports better texture and tone, a healthier scalp sets the stage for stronger, fuller hair.

How to Apply OS-01 HAIR

  1. We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
  2. Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose.  Apply the serum directly to your scalp, starting at your natural part or hairline.
  3. Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
  4. Massage the serum into your scalp with your fingertips to ensure even distribution.
  5. Do not rinse. Style as usual.
  6. Use daily on dry or damp hair.

A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.

Your OS-01 HAIR questions answered

HOW IT WORKS

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to target cellular senescence02,09, a biological process linked to hair loss and thinning.03-08

All Ingredients

Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.

OS-01 HAIR SCALP SERUM

4.5
Rated 4.5 out of 5 stars
Based on 182 reviews
Total 5 star reviews: 122 Total 4 star reviews: 35 Total 3 star reviews: 17 Total 2 star reviews: 4 Total 1 star reviews: 4
86%would recommend these products
182 reviews
  • C
    cryssy
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    4 minutes ago
    loving it

    Ok, first thing is i love how weightless this is. It takes a bit of time to absorb in my scalp but it doesn't leave any greasiness and I love the smell of it! I have had significant hair loss. Only been using for about2 months so will update in a few more months but so far I am loving it. hair loss has slowed down a lot. I know hair loss i more about stress and lifestyle but I still need all the extra help i can get espeically with the thinning my hair loss has came with.

  • C
    Charity
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    5 Stars

    I am liking so far. I’ve only been using it for a few days, but I love how it does not make my hair look greasy or oily where I can use it every day even not on wash days thank you. I recommend one skin hair serum.

  • K
    Kirstin
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    2 days ago
    5 Stars

    This is a lightweight scalp serum that feels cooling upon application and enhances my hair styling experience. After several weeks of use, I already feel like my scalp health has started to improve.

  • VG
    Virginia G.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    OS-01 HAIR SCALP SERUM

    I have been using this product for over 8 months and have noted increasing hair thickness in my areas of concern ! Apart from hair growth , the product goes on easily and leaves no residue - easy to use ! I love it !

  • DB
    Denise B.
    Verified Buyer
    Reviewing
    OS-01 HAIR SCALP SERUM
    I recommend this product
    Rated 5 out of 5 stars
    4 days ago
    Just started

    I really like the way you can use this twice a day and it doesn’t make your hair oily. I just started so will see how it does in three months.

Citations

01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259

04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318

05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269 

06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/

07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic 

08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext 

09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/ 

11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/  

12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).