OS-01 HAIR SCALP SERUM
OS-01 HAIR SCALP SERUM
Topical Supplement
Reduce shedding and reactivate the hair growth cycle with our daily scalp serum, powered by the OS-01 Peptide™.01
- Nourishes the scalp, and promotes thicker, fuller, denser hair
- 81% showed a +40% improvement in hair density after 6 months
- Dermatologist tested, fragrance-free, safe for sensitive skin
1 month supply delivered every 1 month.
3 month supply delivered every 3 months.
6 month supply delivered every 6 months.
include dermaroller?
Black Travel Bag + OS-01 EYE Travel Size with your first subscription
- Plastic neutral refillable packaging
- Exclusive early access to new products
- Earn 2x points for free products on all recurring orders
- Easily change, skip or cancel anytime
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BENEFITS
Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01
Prevent a root cause of hair thinning
Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09
Scalp health
Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09
Thicker, denser, fuller hair
Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01
CLINICAL DATA
Visible results, scientifically validated
81
of participants showed an increase in hair density (average +40%) after 6 months 01
78
participants showed an increase in hair thickness (average +43%) after 6 months 01
81
of participants observed overall improvements in their hair after 3 months 01
78
of participants said the overall health of their hair improved after 6 months 01
5-STAR REVIEWS
See why customers love OS-01 HAIR
"Just fantastic regrowth in areas where I desperately needed it." — LaDonna L., Beta Tester
"It worked so well! No irritation and dried without leaving a residue." — Jodi F., Beta Tester
"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routine—and yes, I will pay it. After a certain age, you pay what you must—not to look younger, but to look your best." — Queen E., Beta Tester
The proof is in the pictures
What makes OS-01 HAIR unique?
- Model
- Proprietary ingredient
- No harsh side effects
- Lightweight & non-greasy
- Drug-free
- No prescription
- Supports scalp health
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OS-01 HAIR
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Prescription Hair Treatments
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Leading Supplement
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- N/A
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Leading Hair Serum
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Invasive Treatments (PRP, hair transplant, etc.)
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DIY Oils
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The science behind OS-01 HAIR
The science behind OS-01 HAIR
Your scalp ages just like the rest of your skin. But instead of lines and wrinkles, the accumulation of senescent cells impairs how your hair follicles function, leading to thinner, weaker strands over time.03-05
OS-01 HAIR was developed to target this issue at the root. It’s the first and only scalp serum powered by the OS-01 peptide, scientifically proven to reduce cellular senescence—a key driver of age-related hair thinning.02,09
When tested on senescence-induced cells in the lab, OS-01 HAIR significantly reduced senescence, reinforcing OS-01 HAIR’s potential to address one of the core biological processes behind age-related thinning and hair loss.03-09
Just like healthy skin supports better texture and tone, a healthier scalp sets the stage for stronger, fuller hair.
6 active ingredients complement the OS-01 peptide
How to Apply OS-01 HAIR
- We recommend applying one full pipette (2 squeezes) to the entire scalp during each application.
- Fill the glass pipette by squeezing the applicator bulb, one squeeze will give you half the application dose. Apply the serum directly to your scalp, starting at your natural part or hairline.
- Refill the glass pipette again, with a second squeeze, and continue applying to areas of concern to complete the full dose.
- Massage the serum into your scalp with your fingertips to ensure even distribution.
- Do not rinse. Style as usual.
- Use daily on dry or damp hair.
A 50 mL bottle of OS-01 HAIR should last approximately 30 days with regular use.
Your OS-01 HAIR questions answered
All Ingredients
Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran Water, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.
OS-01 HAIR SCALP SERUM
- SCSuchen C.Verified BuyerReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars1 hour agoResult within two weeks of using
I almost never write any reviews. However, I really want to share my experiences about this product. For the past year or two, I started noticing my hair was falling out at a crazy rate to the extent where I was too scared to look at the hair collected at the drain traps. I tried several things but did not see any result until OS-01 Hair. I saw a great deal of new growth and best of all, the crazy shedding stopped. I no longer saw a substantial quantity of hair in drain traps. This is only my 2nd bottle and the result I am seeing is undeniable.
- SGSheryl G.Verified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 5 out of 5 stars21 hours agoGreat for dry scalp
I got this for my husband because he’s had a very dry scalp for years. He gets dried spots, then picks at them which makes everything worse. We’ve tried so many different things to help that he’s got a drawer full, nothing really worked. He’s been using the scalp serum for about 10 days and it’s already helping to clear up those dry spots and there hasn’t been more new ones. It’s too early to tell if it’ll help grow any hair, but this is a great start!
- VCVictoria C.ReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 4 out of 5 stars6 days agoBottle #2 & Still Using
I’m on bottle #2 of the OneSkin Hair Serum and I do like it so far. It’s very lightweight and truly doesn’t make my hair look dirty or greasy — which I’ve experienced with other brands that claim the same. I’m not seeing a dramatic transformation yet, but I am noticing less shedding, a little new growth, and overall healthier-looking hair.
For transparency, I’m also following the Abbey Young method, taking beef liver and Nutrafol, and I recently added a derma roller. On hair wash days, I derma-roll my scalp before applying the serum and always use a scalp massager to really work it in. So my results are likely a combination of everything, but I appreciate how easy this serum is to use and that it doesn’t weigh my hair down. I’ll continue using and update over time.
OneSkin3 minutes agoHi Victoria! Thank you so much for your thoughtful feedback about OS-01 HAIR! We're absolutely thrilled to hear that you're on your second bottle and experiencing such great results - less shedding, new growth, and overall healthier-looking hair sounds fantastic!
It's wonderful that you're loving the lightweight formula and that it truly doesn't weigh your hair down or create that greasy look you've experienced with other products. That comfortable, easy-to-use experience is exactly what we're so passionate about delivering with our scalp serum.
We really appreciate your transparency about combining OS-01 HAIR with other methods - it's great that you've found a comprehensive routine that works for you, and we're so glad our serum fits seamlessly into your regimen with the derma rolling and scalp massage.
It sounds like you're already seeing wonderful progress, and we're excited for you to continue your journey with OS-01 HAIR over time. Stories like yours about consistent use and the healthy improvements you're noticing truly mean so much to us.
Thank you for taking the time to share such detailed feedback about your experience - your 4-star review and commitment to the process truly mean the world to all of us at OneSkin and we are always here to support you if you need anything!
- BbeachyVerified BuyerReviewingOS-01 HAIR SCALP SERUMI recommend this productRated 4 out of 5 stars2 weeks agoI think it’s working
my husband has been using this for a solid 2+ months and his har does appear to be a bit thicker. He notices that his dandruff has completely gone away……
OneSkin1 week agoHi beachy! Thank you so much for sharing your wonderful feedback about OS-01 HAIR. We are absolutely thrilled to hear that your husband has been so consistent with his routine for over two months and that you're both noticing such positive changes.
It's fantastic to hear that his hair appears thicker and that the dandruff has completely disappeared - those are exactly the kind of transformative benefits we're so passionate about delivering! The fact that you're seeing these improvements after consistent use is truly wonderful, and it sounds like his scalp is responding beautifully to the serum.
Thank you for taking the time to share such thoughtful feedback about your experience. Please reach out to us if you ever need anything!
- JJacquelynReviewingOS-01 HAIRI recommend this productRated 5 out of 5 stars2 weeks ago5 Stars
My hair feels healthier and stronger. Thicker also. Feels great
Related Articles
Citations
01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.
02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259
04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318
05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269
06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/
07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-Androgenetic
08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltext
09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/
11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/
12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).