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Discover the science behind every lab claim

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OS-01 Peptide™

Lab Data

OS-01 Peptide™ — Lab Data
Category Key claim Clinical details
Biological Age

The OS-01 Peptide™ reverses skin's biological age.

Based on ex vivo lab studies measuring epigenetic markers and using a skin-specific molecular clock which indicate skin's biological age (Zonari et al., npj Aging, 2023; Boroni et al., Clinical Epigenetics, 2020). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Cellular Senescence

The OS-01 Peptide™ reduces senescence in skin.

The OS-01 Peptide™ reduces SASP-secreting cells, slowing the spread and accumulation of senescence in skin.

Based on ex vivo and in vitro lab studies measuring levels of senescence and senescence-associated biomarkers (CDKN2A/P16, CDKN1A/P21, H2A.J, CXCL8 and IL-6) which indicate reduction in senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Repair

The OS-01 Peptide™ supports skin's natural repair processes.

Based on in vitro lab studies measuring cellular damage biomarker, γH2A.x, and evaluating PP2A, involved in cellular repair, which indicate repair processes (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
UV-induced senescence / UV aging

The OS-01 Peptide™ reduces/prevents UV-induced senescence / UV aging in skin by 42.5%.

Based on in vitro lab studies measuring levels of senescence before and after UVB exposure which indicate UV-induced senescence and aging (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
UV-induced inflammation

The OS-01 Peptide™ reduces/prevents UV-induced inflammation biomarkers in skin.

Based on in vitro lab studies measuring inflammation biomarkers (IL-6 and CCL2) before and after UVB exposure which indicate UV-induced inflammation (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Dark Spots

The OS-01 Peptide™ targets the appearance of dark spots at the cellular level.

Based on in vitro lab studies measuring melanin which indicate the appearance of dark spots (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Inflammation

The OS-01 Peptide™ reduces a key inflammation biomarker in skin.

Based on ex vivo lab studies measuring inflammation biomarker (IL-6) which indicate inflammation (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Hyaluronic Acid

The OS-01 Peptide™ increases a key hyaluronic acid production biomarker in skin by 246% / promotes hyaluronic acid production in skin by 246%.

Based on ex vivo lab studies measuring hyaluronic acid production biomarker (HAS2) which indicate hyaluronic acid production (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Collagen

The OS-01 Peptide™ increases a key collagen production biomarker in skin by 179% / promotes collagen production in skin by 179%.

Based on ex vivo lab studies measuring collagen production biomarker (COL1A1) which indicate collagen production (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Keratin

The OS-01 Peptide™ increases key keratin production biomarkers in skin / promotes keratin production in skin.

Based on ex vivo lab studies measuring keratin production biomarkers (KRT1 and KRT14) which indicate keratin production (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Senescence in hair

The OS-01 Peptide™ targets senescence in hair.

The OS-01 Peptide™ significantly reduces a key senescence biomarker in stressed hair cells.

Based on in vitro lab studies measuring senescence biomarker (CDKN1A/P21) which indicate senescence. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Skin barrier & hydration retention

The OS-01 Peptide™ improves skin barrier strength/hydration retention after 6 weeks.

 

After 6 weeks, the side treated with the OS-01 formulation showed nearly 4 times greater improvement in skin barrier strength/hydration retention than the control side.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and measured with a vapometer. Effects of the peptide were isolated by evaluating the difference in barrier function between skin treated with OS-01 FACE MOISTURIZER versus an identical formulation without the OS-01 Peptide (vehicle formulation). A significant improvement was observed between skin treated with OS-01 FACE MOISTURIZER versus the vehicle formulation (18.9% vs. 5.0% reduction in TEWL loss from baseline; p=0.012). (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Skin texture

The OS-01 Peptide™ improves/smooths skin texture after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and measured with an Antera 3D. Effects of the peptide were isolated by evaluating the difference in texture between skin treated with OS-01 FACE MOISTURIZER versus an identical formulation without the OS-01 Peptide (vehicle formulation). A significant improvement was observed between skin treated with OS-01 FACE MOISTURIZER versus the vehicle formulation (p=0.030).  (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).

OS-01 FACE MOISTURIZER

Lab Data

OS-01 FACE MOISTURIZER — Lab Data
Category Key claim Clinical details
Aging/senescence

OS-01 FACE MOISTURIZER reduces key aging/senescence biomarkers in skin.

Based on ex vivo lab studies measuring levels of senescence biomarkers (CDKN2A and B2M) which indicate senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Collagen

OS-01 FACE MOISTURIZER increases a key collagen production biomarker in skin y 51% / promotes collagen production in skin by +51%.

Based on ex vivo lab studies measuring collagen production biomarker (COL1A1) which indicate collagen production (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
OS-01 FACE MOISTURIZER vs Retinol – Collagen

OS-01 FACE MOISTURIZER and retinol both increase a key collagen production biomarker in skin / promote collagen production in skin in the acute phase of treatment.

Based on ex vivo lab studies measuring collagen production biomarker (COL1A1) which indicates collagen production (Zonari, A., et al. npj Aging, 2023). These results represent acute responses to the products after 5 days of exposure, and may not reflect long-term results. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
OS-01 FACE MOISTURIZER vs Retinol – Aging/Senescence

Retinol increases a key aging/senescence biomarker more than 10-fold in the epidermis versus untreated skin, while OS-01 FACE MOISTURIZER significantly reduces it, in the acute phase of treatment.

Based on ex vivo lab studies measuring senescence biomarker (CDKN2A) which indicates senescence (Zonari, A., et al. npj Aging, 2023). These results represent acute responses to the products after 5 days of exposure, and may not reflect long-term results. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Skin barrier

OS-01 FACE MOISTURIZER improves skin barrier strength/resilience by 19% after 6 weeks, shown in 81% of users. 

OS-01 FACE MOISTURIZER improves skin barrier strength/resilience by 14% after 12 weeks, shown in 80% of users.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and measured with a vapometer. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Hydration retention

OS-01 FACE MOISTURIZER improves skin hydration retention in 81% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and measured with a vapometer.(Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Elasticity

OS-01 FACE MOISTURIZER improves skin elasticity in 68% of users after 6 weeks. OS-01 FACE MOISTURIZER improves skin elasticity in 91% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader tactile evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Skin tone

OS-01 FACE MOISTURIZER evens skin tone in 55% of users after 6 weeks. OS-01 FACE MOISTURIZER evens skin tone in 96% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Radiance

OS-01 FACE MOISTURIZER improves visible radiance in 96% of users after 12 weeks.

OS-01 FACE MOISTURIZER improves skin radiance by +17% after 12 weeks, shown in 73% of users.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Pores

OS-01 FACE MOISTURIZER reduces the look of pores in 77% of users after 6 weeks.

OS-01 FACE MOISTURIZER reduces the look of pores in 96% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Firmness

OS-01 FACE MOISTURIZER improves visible firmness in 91% of users after 6 weeks.

OS-01 FACE MOISTURIZER improves visible firmness in 96% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Fine lines & wrinkles

OS-01 FACE MOISTURIZER reduces the appearance of fine lines and wrinkles in 55% of users after 6 weeks.

OS-01 FACE MOISTURIZER reduces the appearance of fine lines and wrinkles in 86% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Smoothness

OS-01 FACE MOISTURIZER improves visible skin smoothness / visibly smooths skin in 86% of users after 6 weeks.

OS-01 FACE MOISTURIZER improves visible skin smoothness / visibly smooths skin in 100% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Overall appearance

OS-01 FACE MOISTURIZER improves overall appearance in 82% of users after 6 weeks.

OS-01 FACE MOISTURIZER improves overall appearance in 100% of users after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65, and analyzed via double-blind expert clinical grader visual evaluation. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Skin microbiome

OS-01 FACE MOISTURIZER is clinically validated to support skin's microbiome. Participants displayed a significant positive shift of the microbiome grade after treatment compared to baseline. No significant changes in the ratio of bacteria to fungi were detected after treatment compared to baseline.

Shown in a 6-week clinical study performed by a third party research organization (HelloBiome) with 38 participants who collected samples of their facial skin microbiome before and after treatment with OS-01 FACE MOISTURIZER for 6 weeks. Using next generation sequencing and existing research, HelloBiome determined that OS-01 FACE MOISTURIZER supports skin's microbiome.
Non-comedogenic

OS-01 FACE MOISTURIZER is non-comedogenic.

Based on a third-party 4-week single-blind clinical study with 33 participants assessing comedogenic potential via repeated occlusive cutaneous patch applications and follicular biopsy.
Sensitive skin

OS-01 FACE MOISTURIZER is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 54 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 FACE MOISTURIZER has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT performed on 108 participants.

Consumer Perception Data

Claims table — Consumer Perception Data
Category Key claim Clinical details
Hydration

86% agreed their skin felt more hydrated after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Tone & Texture

82% agreed their skin felt and looked smoother and more even toned after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Radiance

77% agreed their skin looked more radiant after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Firmness/Elasticity

86% agreed their skin looked/felt firmer and more elastic after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65.(Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Overall Appearance

86% agreed the overall appearance of their skin improved after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024).
Dark spots

68% agreed their dark spots improved after 6 weeks.

Based on a third-party 6-week clinical study with 38 participants aged 40–60. Data unpublished.
Eye bags

68% agreed their eye bags improved after 6 weeks.

Based on a third-party 6-week clinical study with 38 participants aged 40–60. Data unpublished.
Acne & visible redness

52% agreed that skin issues such as acne and visible redness improved after 6 weeks.

Based on a third-party 6-week clinical study with 38 participants aged 40–60. Data unpublished.

OS-01 EYE CREAM

Lab Data

OS-01 EYE CREAM — Lab Data
Category Key claim Clinical details
Collagen Degradation

OS-01 EYE CREAM reduces a key collagen degradation biomarker in skin / helps reduce collagen breakdown in skin.

Based on ex vivo lab studies measuring collagen degradation biomarker (MMP1) which indicate collagen degradation (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Collagen

OS-01 EYE CREAM increases collagen by 2.3x (+130%).

Based on ex vivo lab studies measuring collagen (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Aging/senescence

OS-01 EYE CREAM reduces a key cellular senescence and aging biomarker in skin.

Based on ex vivo lab studies measuring levels of senescence biomarkers (CDKN2A) which indicate senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Inflammation

OS-01 EYE CREAM reduces a key inflammation biomarker in skin.

Based on ex vivo lab studies measuring inflammation biomarker (IL-8) which indicates inflammation (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Hydration

OS-01 EYE CREAM improves skin hydration. 1 month: Avg improvement of +20%, shown in 83% of users. 3 months: Avg improvement of +32%, shown in 88% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Hydration retention

OS-01 EYE CREAM improves skin hydration retention in 70% of users after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Elasticity

OS-01 EYE CREAM improves skin elasticity. 1 month: Avg improvement of +14%, shown in 77% of users. 3 months: Avg improvement of +26%, shown in 86% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Elasticity (visible)

OS-01 EYE CREAM improves visible elasticity. 6 months: Avg improvement of +23%, shown in 78% of users. 12 months: Avg improvement of +29%, shown in 76% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Firmness

OS-01 EYE CREAM improves skin firmness. 1 month: Avg improvement of +6%, shown in 68% of users. 3 months: Avg improvement of +10%, shown in 73% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Firmness (visible)

OS-01 EYE CREAM improves visible firmness. 6 months: Avg improvement of +19%, shown in 70% of users. 12 months: Avg improvement of +27%, shown in 72% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Skin barrier

OS-01 EYE CREAM improves skin barrier function/strength/resilience. 1 month: Avg improvement of +10%, shown in 61% of users. 3 months: Avg improvement of +17%, shown in 70% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Skin Tone

OS-01 EYE CREAM improves skin tone by 17% after 12 months, shown in 63% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Skin Texture

OS-01 EYE CREAM visibly improves / smooths skin texture by 22% after 12 months, shown in 70% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Radiance

OS-01 EYE CREAM improves visible radiance by 25% after 12 months, shown in 65% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Under-eye puffiness

OS-01 EYE CREAM visibly reduces under-eye puffiness. 1 month: Avg improvement of 8%, shown in 50% of users. 3 months: Avg improvement of 11%, shown in 59% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65.(Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Fine lines & wrinkles

OS-01 EYE CREAM reduces the appearance of fine lines and wrinkles. 1 month: Avg reduction of 6%, shown in 45% of users. 3 months: Avg reduction of 7%, shown in 59% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Fine lines & wrinkles (12 months)

OS-01 EYE CREAM reduces the appearance of fine lines and wrinkles. 12 months: Avg reduction of 18%, shown in 63% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Dark Circles

OS-01 EYE CREAM reduces the appearance of dark circles by 7% after 3 months, shown in 50% of users.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Pores

OS-01 EYE CREAM reduces the look of pores by 21% after 12 months, shown in 70% of users.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Non-comedogenic

OS-01 EYE CREAM is non-comedogenic.

Based on a third-party 4-week single-blind clinical study with 33 participants assessing comedogenic potential via repeated occlusive cutaneous patch applications and follicular biopsy.
Sensitive skin

OS-01 EYE CREAM is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 54 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 EYE CREAM has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT study performed on 108 participants.

Consumer Perception Data

Claims table — Consumer Perception Data
Category Key claim Clinical details
Hydration

91% agreed their skin felt more hydrated after 1 month. 86% agreed their skin felt more hydrated after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Hydration (6 months)

96% agreed their skin felt more hydrated after 6 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Firmness/Elasticity

86% agreed their skin felt/looked firmer and more elastic after 1 month. 82% agreed their skin felt/looked firmer and more elastic after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Firmness/Elasticity (6 & 12 months)

96% agreed their skin felt/looked firmer and more elastic after 6 months. 95% agreed their skin felt/looked firmer and more elastic after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Tone & Texture

95% of users agreed their skin felt and looked smoother and more even toned after 1 month. 91% of users agreed their skin felt and looked smoother and more even toned after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Tone & Texture (6 & 12 months)

96% of users agreed their skin felt and looked smoother and more even toned after 6 months. 96% of users agreed their skin felt and looked smoother and more even toned after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Radiance

91% of users agreed their skin looked more radiant after 1 month. 86% of users agreed their skin looked more radiant after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Radiance (6 & 12 months)

96% of users agreed their skin looked more radiant after 6 months. 100% of users agreed their skin looked more radiant after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Dark spots

82% agreed their dark spots improved after 1 month. 77% agreed their dark spots improved after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Dark spots (6 & 12 months)

86% agreed their dark spots improved after 6 months. 86% agreed their dark spots improved after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Under-eye puffiness

68% agreed their under-eyes looked less puffy after 1 month. 77% agreed their under-eyes looked less puffy after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Eye bags

83% agreed the appearance of their eye bags improved after 6 months. 86% agreed the appearance of their eye bags improved after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.
Overall Appearance

91% agreed the overall appearance of their skin improved after 1 month. 95% agreed the overall appearance of their skin improved after 3 months.

Based on a third-party 12-week clinical study with 22 participants aged 47–65. (Zonari, A., et al. International Journal of Cosmetic Science, 2025).
Overall Appearance (6 & 12 months)

96% agreed the overall appearance of their skin improved after 6 months. 100% agreed the overall appearance of their skin improved after 12 months.

Based on a third-party 12-month clinical study with 23 participants aged 47–60. Data unpublished.

OS-01 BODY MOISTURIZER

Lab Data

OS-01 BODY MOISTURIZER — Lab Data
Category Key claim Clinical details
Collagen

OS-01 BODY MOISTURIZER increases collagen production by +23%.

Based on ex vivo lab studies measuring pro-collagen, a precursor protein to collagen, which indicates collagen production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Hydration

OS-01 BODY MOISTURIZER improved skin hydration by 38% after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
Skin barrier

OS-01 BODY MOISTURIZER improves skin barrier function/strength/resilience by 41% after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
OS-01 Peptide penetration into bloodstream

The OS-01 Peptide™ does not accumulate in the bloodstream when applied topically with OS-01 BODY MOISTURIZER.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
Non-comedogenic

OS-01 BODY MOISTURIZER is non-comedogenic.

Based on a third-party 4-week single-blind clinical study with 33 participants assessing comedogenic potential via repeated occlusive cutaneous patch applications and follicular biopsy.
Sensitive skin

OS-01 BODY MOISTURIZER is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 54 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 BODY MOISTURIZER has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT study performed on 114 participants.

Consumer Perception Data

Claims table — Consumer Perception Data
Category Key claim Clinical details
Hydration

71.43% agreed their body skin felt more hydrated after 4 weeks.

93% agreed their skin felt more hydrated after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
Texture

68% agreed their body skin felt and looked smoother after 4 weeks.

70% of users agreed their skin felt and looked smoother after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
General Appearance

70% agreed the general appearance of their skin improved after 12 weeks.

Based on a double-blind, third-party 12-week clinical study with 27 participants aged 62–82. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2025).
Non-comedogenic

OS-01 BODY MOISTURIZER is non-comedogenic.

Based on a third-party 4-week single-blind clinical study with 33 participants assessing comedogenic potential via repeated occlusive cutaneous patch applications and follicular biopsy.
Sensitive skin

OS-01 BODY MOISTURIZER is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 54 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 BODY MOISTURIZER has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT study performed on 114 participants.

OS-01 HAIR SCALP SERUM

Lab Data

OS-01 HAIR SCALP SERUM — Lab Data
Category Key claim Clinical details
Age-related thinning

OS-01 HAIR SCALP SERUM targets a root cause of age-related hair thinning – cellular senescence.

Based on ex vivo and in vitro lab studies measuring levels of senescence and senescence-associated biomarkers (CDKN2A/P16, CDKN1A/P21, H2A.J, CXCL8 and IL-6) which indicate reduction in senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Stress-related hair thinning

OS-01 HAIR SCALP SERUM reduces CRH-induced senescence. CRH is a stress hormone, therefore this data suggests that OS-01 HAIR SCALP SERUM may be a potential candidate for addressing stress-induced hair thinning.

Based on in vitro lab studies measuring levels of senescence and senescence-associated biomarkers (CDKN2A/P16, CDKN1A/P21, H2A.J, CXCL8 and IL-6) which indicate reduction in senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Pattern thinning

OS-01 HAIR SCALP SERUM targets a potentially exacerbating factor of pattern thinning – cellular senescence.

Based on in vitro lab studies measuring levels of senescence and senescence-associated biomarkers (CDKN2A/P16, CDKN1A/P21, H2A.J, CXCL8 and IL-6) which indicate reduction in senescence (Zonari, A., et al. npj Aging, 2023). Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Inflammation biomarkers

OS-01 HAIR SCALP SERUM significantly reduces a key inflammation biomarker.

Based on in vitro lab studies measuring inflammation biomarker (IL-6) which indicate inflammation. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Hair Cycle

OS-01 HAIR SCALP SERUM supports a healthy hair cycle.

Shown in a 6 month double-blind, independent, third-party clinical study with 32 participants (23 F and 9 M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Hair parameters were measured using HairMetrix® clinical photography, Trichoscopy and Phototrichogram. Data unpublished.
Hair Density

OS-01 HAIR SCALP SERUM increases hair density by +40% after 6 months, shown in 81% of users. OS-01 HAIR SCALP SERUM shows continued increase in hair density between 3 and 6 months (+15%).

Shown in a 6-month double-blind, independent, third-party clinical study with 32 participants (23 F and 9 M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Hair parameters were measured using HairMetrix® clinical photography, Trichoscopy and Phototrichogram. After 6 months, 81% of participants experienced a 40% average increase in hair density (hair count per cm²) compared to baseline (p = 0.00003). Participants saw a significant 15% increase in hair density (hair count per cm²) between 3 and 6 months (p = 0.00167). Data unpublished.
Hair Thickness

OS-01 HAIR SCALP SERUM increases hair thickness by +43% after 6 months, shown in 78% of users. OS-01 HAIR SCALP SERUM shows continued increase in hair thickness between 3 and 6 months (+15%).

Shown in a 6-month double-blind, independent, third-party clinical study with 32 participants (23 F and 9 M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Hair parameters were measured using HairMetrix® clinical photography, Trichoscopy and Phototrichogram. After 6 months, 78% of participants experienced a 43% average increase in hair thickness (sum of hair widths) compared to baseline (p = 0.00001). Participants saw a significant 15% increase in hair thickness (sum of hair widths) between 3 and 6 months (p = 0.00115). Data unpublished.
Grey Hair

OS-01 HAIR SCALP SERUM can reduce the appearance of grey hair.

Shown in a 6-month double-blind, independent, third-party clinical study with 24 participants (23 F and 9 M), ages 27–55, with grey hair using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. After 6 months, 37% of participants experienced a significant improvement in the overall appearance of hair pigment (grey hair) compared to baseline, based on visual hair pigment (grey) grading by a trained clinical expert grader (p = 0.01). Data unpublished.
Scalp microbiome

OS-01 HAIR SCALP SERUM is clinically validated to support the scalp microbiome, with: significant increase in bacterial diversity, significant decrease in species known to increase with hair thinning, significant increase in species known to decrease with hair thinning. No significant changes in fungal diversity detected after treatment.

Based on a 6-month clinical study by a third-party research organization (HelloBiome) with 30 participants aged 25–55. Scalp microbiome samples collected before and after 6 months of OS-01 HAIR SCALP SERUM treatment, analyzed by next-generation sequencing. Data unpublished.

Reference: Saxena et al., 2018; Ergin et al., 2024.

Sensitive skin

OS-01 HAIR SCALP SERUM is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 55 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 HAIR SCALP SERUM has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT study performed on 105 participants.

Consumer Perception Data

Claims table — Consumer Perception Data
Category Key claim Clinical details
Hair shedding

72% reported decreased visible shedding after 6 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Hair volume/fullness

75% said their hair appears fuller after 3 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
General improvements

81% observed visible improvements in their hair after 3 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Overall hair health

78% observed visible improvement in the overall health of their hair after 3 months and after 6 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
New hair

75% observed the appearance of new hair after 3 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Scalp nourishment

72% said their scalp feels more nourished after 3 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Hair nourishment

78% said their hair felt nourished after 6 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Hair strength

75% reported stronger hair after 6 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Perceived growth rate

72% said existing hair grew faster after 6 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Hair texture

72% said hair's natural texture was enhanced.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Styling

89% agreed they were able to style their hair like usual.

Based on a 3-month beta test (brand-led consumer perception study) with 22 participants aged 25–74 using OS-01 HAIR SCALP SERUM 1–2x daily (no dermaroller). Data unpublished.
Product texture

85% agreed the product is lightweight.

Based on a 3-month beta test (brand-led consumer perception study) with 22 participants aged 25–74 using OS-01 HAIR SCALP SERUM 1–2x daily (no dermaroller). Data unpublished.
Scalp hydration

81% agreed their scalp felt more hydrated after 2 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.
Hair density (perceived)

73% saw visibly denser hair (more hairs on their heads) after 3 months.

Based on a 6-month, double-blind, independent, third-party clinical study with 32 participants (23F, 9M), ages 27–55, using OS-01 HAIR SCALP SERUM twice daily and dermarolling once daily. Results based on self-reported participant perception. Data unpublished.

OS-01 LIP MASK

Lab Data

OS-01 LIP MASK — Lab Data
Category Key claim Clinical details
Collagen

OS-01 LIP MASK increases key collagen production biomarker in skin by +138% / promotes collagen production in skin by +138%.

Based on ex vivo lab studies measuring collagen production biomarker (COL1A1) which indicate collagen production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Collagen (vs luxury lip mask)

OS-01 LIP MASK increases key collagen production biomarker (COL1A1) in skin by +101% more than a luxury award-winning lip mask / promotes collagen production in skin by +101% more than a luxury award-winning lip mask.

Based on ex vivo lab studies measuring collagen production biomarker (COL1A1) which indicate collagen production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Elastin

OS-01 LIP MASK increases key elastin production biomarker in skin by +133% / promotes elastin production in skin by +133%.

Based on ex vivo lab studies measuring elastin production biomarker (ELN) which indicate elastin production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Elastin (comparative)

OS-01 LIP MASK increases key elastin production biomarker in skin / promotes elastin production in skin more than comparative products:

+135% vs. leading drugstore lip product; +101% vs. market leading peptide lip treatment; +67% vs. luxury award-winning lip mask.

Based on ex vivo lab studies measuring elastin production biomarker (ELN) which indicate elastin production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Hyaluronic Acid

OS-01 LIP MASK increases key hyaluronic acid production biomarker (HAS2) in skin by +51% / promotes hyaluronic acid production in skin by +51%.

Based on ex vivo lab studies measuring hyaluronic acid production biomarker (HAS2) which indicate hyaluronic acid production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Hyaluronic Acid (vs drugstore)

OS-01 LIP MASK increases key hyaluronic acid production biomarker (HAS2) in skin by +41% / promotes hyaluronic acid production in skin by +41% more than a leading drugstore lip product.

Based on ex vivo lab studies measuring hyaluronic acid production biomarker (HAS2) which indicate hyaluronic acid production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Senescence/aging

OS-01 LIP MASK decreases key senescence/aging biomarker compared to leading competitors:

−17% vs. market leading peptide lip treatment; −17% vs. leading drugstore lip product.

Based on ex vivo lab studies measuring levels of senescence biomarker (CDKN1A/P21) which indicates senescence. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

Clinical Data

Claims table — Clinical Data
Category Key claim Clinical details
Non-comedogenic

OS-01 LIP MASK is non-comedogenic.

Based on a third-party 4-week single-blind clinical study with 34 participants assessing comedogenic potential via repeated occlusive cutaneous patch applications and follicular biopsy.
Sensitive skin

OS-01 LIP MASK is suitable for sensitive skin & dermatologically tested.

Based on a third-party clinical study with 64 healthy volunteers assessed by means of repeated cutaneous occlusive patch applications.
Eczema

OS-01 LIP MASK has been awarded the National Eczema Association Seal of Acceptance™ by the National Eczema Association (NEA).

NEA Seal of Acceptance™ awarded by the National Eczema Association. RIPT study performed on 107 participants.

Consumer Perception Data

Claims table — Consumer Perception Data
Category Key claim Clinical details
Use

100% agreed OS-01 LIP MASK is enjoyable to use.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Hydration (instant)

98% agreed lips feel instantly hydrated and moisturized upon application.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Hydration (overnight)

98% agreed lips feel hydrated and moisturized the next morning (8+ hours after application).

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Hydration (instant + long-lasting)

98% agreed OS-01 LIP MASK delivers both instant and long-lasting hydration (8+ hours).

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Ultra-hydrating

95% agreed OS-01 LIP MASK is ultra-hydrating.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Hydration retention (4 weeks)

90% agreed lips retain hydration for longer after 4 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Hydration retention (12 weeks)

94% agreed lips retain hydration for longer after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Taste

98% agreed OS-01 LIP MASK does not have an off-putting taste.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Satisfaction

98% would recommend OS-01 LIP MASK to friends and family.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Tingly

95% agreed OS-01 LIP MASK is non-tingly.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Application

95% agreed OS-01 LIP MASK applies smoothly.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Moisturization

95% agreed OS-01 LIP MASK deeply moisturizes lips.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Dryness, damage

92% agreed OS-01 LIP MASK helps soothe visibly dry, damaged lips.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Smoothness

90% agreed lips feel and look smoother after 2 weeks. 95% agreed lips feel and look smoother after 4 weeks. 97% agreed lips feel and look smoother after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Softness

87% agreed lips feel softer after 2 weeks. 95% agreed lips feel softer after 4 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Health

93% agreed lips feel and look healthier after 4 weeks. 97% agreed lips feel and look healthier after 8 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Fine lines & wrinkles (around lips)

81% who applied OS-01 LIP MASK around their lip border reported reduced appearance of fine lines and wrinkles around their lips after 4 weeks. 81% who applied OS-01 LIP MASK around their lip border reported reduced appearance of fine lines and wrinkles around their lips after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Fine lines & wrinkles (on lips)

80% reported reduced appearance of fine lines and wrinkles on their lips after 4 weeks. 84% reported reduced appearance of fine lines and wrinkles on their lips after 8 weeks. 87% reported reduced appearance of fine lines and wrinkles on their lips after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Fullness

78% reported improved visible fullness after 4 weeks. 81% reported improved visible fullness after 8 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Overall appearance

88% agreed the overall appearance of lips improved after 8 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Resilience

81% agreed lips feel more resilient after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.
Lip color

72% agreed the natural color of their lips improved after 12 weeks.

Based on a 12-week beta test (brand-led consumer perception study) with 31 participants aged 35–74, using nightly application of OS-01 LIP MASK. Data unpublished.

OS-01 LIP SPF

Lab Data

OS-01 LIP SPF — Lab Data
Category Key claim Clinical details
Effects of UV-induced stress

OS-01 LIP SPF (untinted) protects skin from the effects of UV-induced stress by reducing inflammation, degradation, and senescence/aging biomarkers in skin:

UV-induced inflammation biomarker by 103%

UV-induced degradation biomarker by 87%

UV-induced senescence/aging biomarker by 104%

Based on ex vivo lab studies measuring levels of inflammation, degradation, and senescence/aging biomarkers (IL-8, MMP3, and CDKN1A/P21) before and after UVB exposure which indicate UV-induced skin stress. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Senescence/aging

OS-01 LIP SPF (untinted) reduces existing senescence and aging biomarkers:

CDKN1A/P21 by −20%

CDKN2A/P16 by −21%

Based on ex vivo lab studies measuring levels of senescence biomarkers (CDKN2A/P16 and CDKN1A/P21) which indicate reduction in existing senescence. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Elastin

OS-01 LIP SPF (untinted) increases key elastin production biomarker by +47% / promotes elastin production in skin by +47%.

Based on ex vivo lab studies measuring elastin production biomarker (ELN) which indicate elastin production. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

OS-01 FACE SPF

OS-01 FACE SPF
Category Key claim Clinical details
UV-induced senescence

OS-01 FACE SPF protects against UV-induced senescence, superior to regular sunscreen.

Based on ex vivo lab studies measuring levels of senescence biomarker (P16 / CDKN2A) before and after UVB exposure which indicate UV-induced senescence and aging. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Senescence/aging

OS-01 FACE SPF reduces existing senescence/aging biomarkers in skin.

OS-01 FACE SPF reduces effects of past aging in skin.

Based on ex vivo lab studies measuring levels of senescence biomarkers (CDKN2A/P16) which indicates reduction in senescence. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Inflammation biomarker

OS-01 FACE SPF reduces a key inflammation biomarker in skin.

Based on ex vivo lab studies measuring inflammation biomarker (IL-6) which indicate inflammation. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Antioxidant power

OS-01 FACE SPF scavenges free radicals 4x more effectively than a leading anti-aging antioxidant SPF moisturizer.

Based on lab studies measuring free radical scavenging which indicates antioxidant power. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Antioxidant power (vs vitamin C)

OS-01 FACE SPF performs similarly to common vitamin C serums at neutralizing free radicals.

Based on lab studies measuring free radical scavenging which indicates antioxidant power. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

OS-01 BODY SPF

OS-01 BODY SPF
Category Key claim Clinical details
Collagen

OS-01 BODY SPF protects skin from UV-induced collagen degradation.

Based on ex vivo lab studies measuring levels of collagen before and after UVB exposure. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
UV-induced senescence/aging

OS-01 BODY SPF reduces UV-induced senescence / UV aging in skin.

Based on ex vivo lab studies measuring levels of senescence biomarker (P16) before and after UVB exposure which indicate UV-induced senescence and aging. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
UV-induced inflammation biomarker

OS-01 BODY SPF reduces a UV-induced inflammation biomarker in skin.

Based on ex vivo lab studies measuring levels of inflammation biomarker (IL-8) before and after UVB exposure which indicate UV-induced inflammation. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
UV-induced hyaluronic acid degradation

OS-01 BODY SPF reduces a UV-induced hyaluronic acid degradation biomarker in skin.

Based on ex vivo lab studies measuring levels of hyaluronic acid degradation biomarker (HYAL1) before and after UVB exposure which indicate UV-induced hyaluronic acid degradation. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.

FACE CLEANSER (PREP)

FACE CLEANSER (PREP)
Category Key claim Clinical details
Peptide Absorption

FACE CLEANSER can improve OS-01 Peptide™ absorption by 2.2x.

Based on ex vivo lab studies measuring peptide levels in skin which indicate absorption. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.
Hydration

Compared to using OS-01 FACE MOISTURIZER alone, FACE CLEANSER can significantly increase a key hydration biomarker (AQP3) when used prior to OS-01 FACE MOISTURIZER.

Based on ex vivo lab studies measuring hydration biomarker (AQP3) which indicate hydration. Lab findings may not reflect outcomes in human use and do not represent whole-body aging or medical claims.