Peptides Vs Growth Factors: Which is Better For Skin Longevity?

6 min read

October 04,2024

INGREDIENTS

Peptides Vs Growth Factors: Which is Better For Skin Longevity?

6 min read

October 04,2024

INGREDIENTS

Skincare is going through some big changes! We’re no longer just talking about moisturizing and SPF – we’ve entered the age of high-tech skincare with a whole arsenal of powerful actives, each promising to turn back the clock on aging skin. Some of the most promising developments in recent years have been growth factors and peptides. But what are these ingredients, and how do they work?

01

What Are Growth Factors?

Growth factors (GFs) are proteins found naturally in the body. Think of them as chemical messengers that facilitate communication between cells. They help mediate cell growth, proliferation, and differentiation.[1]In the context of skincare, growth factors are pivotal for wound healing and tissue repair. When your skin is wounded, growth factors accumulate at the injury site to initiate and coordinate the healing process. They can reverse the effects of collagenases, increase collagen levels, and decrease tissue inflammation.[1] As you age, the production and levels of growth factors in your skin decline. This reduction can lead to slower wound healing and increased visible signs of aging. This has made growth factors promising candidates for anti-aging treatments.[2] However, not all growth factors are delivered in the same way. Growth factors can, therefore, be broken into two main categories:

Topical Growth Factors

Topical growth factor products sound pretty exciting, right? But here’s the thing: to work their magic, they have to get through the skin’s outer layer, called the stratum corneum. Unfortunately, most growth factors are on the larger side and are hydrophilic, which means they don’t easily penetrate the skin.[1,3]While topical growth factor products have shown some improvement in collagen levels, skin tone, and texture in clinical studies, these results are often observed in individuals with compromised skin barriers or after skin treatments like laser therapy, microneedling, or chemical peels.[1] However, for those with healthy, intact skin barriers, these products might not deliver as much of a noticeable change since the growth factors can’t reach the dermis and beyond, where they will have an impact.

01

What Are Growth Factors?

Growth factors (GFs) are proteins found naturally in the body. Think of them as chemical messengers that facilitate communication between cells. They help mediate cell growth, proliferation, and differentiation.[1]In the context of skincare, growth factors are pivotal for wound healing and tissue repair. When your skin is wounded, growth factors accumulate at the injury site to initiate and coordinate the healing process. They can reverse the effects of collagenases, increase collagen levels, and decrease tissue inflammation.[1] As you age, the production and levels of growth factors in your skin decline. This reduction can lead to slower wound healing and increased visible signs of aging. This has made growth factors promising candidates for anti-aging treatments.[2] However, not all growth factors are delivered in the same way. Growth factors can, therefore, be broken into two main categories:

Topical Growth Factors

Topical growth factor products sound pretty exciting, right? But here’s the thing: to work their magic, they have to get through the skin’s outer layer, called the stratum corneum. Unfortunately, most growth factors are on the larger side and are hydrophilic, which means they don’t easily penetrate the skin.[1,3]While topical growth factor products have shown some improvement in collagen levels, skin tone, and texture in clinical studies, these results are often observed in individuals with compromised skin barriers or after skin treatments like laser therapy, microneedling, or chemical peels.[1] However, for those with healthy, intact skin barriers, these products might not deliver as much of a noticeable change since the growth factors can’t reach the dermis and beyond, where they will have an impact.

Injectable Growth Factors

In contrast, injected growth factors, such as those delivered through Platelet-Rich Plasma (PRP) therapy, bypass the epidermal barrier, offering direct delivery to the deeper layers of skin. When injected directly into the dermis, these growth factors can accelerate collagen and elastin production, producing firmer, more youthful-looking skin.[1,4] This method can deliver the active ingredients exactly where needed, ensuring that the growth factors have maximum impact. These treatments can have varying results and effects because of the variety of growth factors available.

Injectable Growth Factors

In contrast, injected growth factors, such as those delivered through Platelet-Rich Plasma (PRP) therapy, bypass the epidermal barrier, offering direct delivery to the deeper layers of skin. When injected directly into the dermis, these growth factors can accelerate collagen and elastin production, producing firmer, more youthful-looking skin.[1,4] This method can deliver the active ingredients exactly where needed, ensuring that the growth factors have maximum impact. These treatments can have varying results and effects because of the variety of growth factors available.

02

Challenges with Growth Factors

A big challenge with growth factors is that they’re pretty fragile. These proteins are sensitive molecules that can degrade under various conditions, including exposure to temperature fluctuations and changes in pH. Many growth factors need to be stored at cooler temperatures to maintain their efficacy outside of their natural environment, and their degradation can occur quickly when stored at room temperature.[5]In practical terms, this means that growth factors in topical products may lose their potency before you even apply them. Therefore, it's crucial to research the stability of the growth factors used in your skincare products and treatments, ensuring that they are stored and delivered correctly to provide optimal results.Growth factors can work wonders for your skin, but to see results, it’s best to get them through in-office treatments like PRP. This way, they bypass the skin barrier and are less likely to denature since they are isolated in the office.

02

Challenges with Growth Factors

A big challenge with growth factors is that they’re pretty fragile. These proteins are sensitive molecules that can degrade under various conditions, including exposure to temperature fluctuations and changes in pH. Many growth factors need to be stored at cooler temperatures to maintain their efficacy outside of their natural environment, and their degradation can occur quickly when stored at room temperature.[5]In practical terms, this means that growth factors in topical products may lose their potency before you even apply them. Therefore, it's crucial to research the stability of the growth factors used in your skincare products and treatments, ensuring that they are stored and delivered correctly to provide optimal results.Growth factors can work wonders for your skin, but to see results, it’s best to get them through in-office treatments like PRP. This way, they bypass the skin barrier and are less likely to denature since they are isolated in the office.

03

What Are Peptides?

Peptides are tiny chains of amino acids, typically composed of fewer than 40. Like growth factors, peptides can act as chemical messengers within the body. They can also be precursors for larger proteins like collagen and elastin, vital to maintaining skin structure. In skincare, peptides are celebrated for their diverse roles and potential benefits. They can regulate and boost various bodily functions, regulating homeostasis, stress, immunity, defense, growth, wound healing, DNA repair, and cellular reproduction. Because of their benefits, certain peptides can even have longevity-boosting properties.[6]

03

What Are Peptides?

Peptides are tiny chains of amino acids, typically composed of fewer than 40. Like growth factors, peptides can act as chemical messengers within the body. They can also be precursors for larger proteins like collagen and elastin, vital to maintaining skin structure. In skincare, peptides are celebrated for their diverse roles and potential benefits. They can regulate and boost various bodily functions, regulating homeostasis, stress, immunity, defense, growth, wound healing, DNA repair, and cellular reproduction. Because of their benefits, certain peptides can even have longevity-boosting properties.[6]

04

Categories of Peptides

But peptides aren’t just about building stuff—they have many other jobs, too. Peptides can be categorized into several types based on their functions:

Signal peptides: Like growth factors, these peptides act as chemical messengers to send signals within the body, helping stimulate and regulate specific biological processes. Some promote collagen and elastin synthesis while boosting epidermal cell proliferation, while others modulate melanin production, enhancing skin tone and texture.[6]
Carrier peptides: Acting as transporters, these peptides deliver essential trace elements (like copper) to target areas. They play a crucial role in skin health by stimulating collagen synthesis and improving skin elasticity.[6]
Neurotransmitter-inhibitor peptide: Mimicking the effects of Botox, peptides like argireline can prevent muscle contractions, leading to a smoother appearance. Others can help moisturize the skin and inhibit melanin synthesis.[6]
Enzyme-inhibitor peptides: By inhibiting enzymes that break down collagen and other proteins, these peptides can reduce skin aging and promote moisture retention.[6]

04

Categories of Peptides

But peptides aren’t just about building stuff—they have many other jobs, too. Peptides can be categorized into several types based on their functions:

Signal peptides: Like growth factors, these peptides act as chemical messengers to send signals within the body, helping stimulate and regulate specific biological processes. Some promote collagen and elastin synthesis while boosting epidermal cell proliferation, while others modulate melanin production, enhancing skin tone and texture.[6]
Carrier peptides: Acting as transporters, these peptides deliver essential trace elements (like copper) to target areas. They play a crucial role in skin health by stimulating collagen synthesis and improving skin elasticity.[6]
Neurotransmitter-inhibitor peptide: Mimicking the effects of Botox, peptides like argireline can prevent muscle contractions, leading to a smoother appearance. Others can help moisturize the skin and inhibit melanin synthesis.[6]
Enzyme-inhibitor peptides: By inhibiting enzymes that break down collagen and other proteins, these peptides can reduce skin aging and promote moisture retention.[6]

05

Peptides' Role in Skin Health

Peptides are superstars when it comes to skin health. Due to their size, they can often penetrate the skin barrier more effectively than growth factors, allowing their active benefits to be delivered more directly to the skin’s deeper layers.[6,7] Unlike growth factors, peptides represent an extremely broad range of molecules. Not all peptides are equal, and their activity within the skin, stability, and ability to penetrate the skin depends on the individual peptide used. It’s essential to make sure that the peptide:

Reaches the right skin layer to do its job. Look for penetration studies to ensure the peptide is penetrating to the dermis layer of skin.
Stays stable in its packaging. Look for stability testing on the peptide, especially at various temperatures.
Delivers the results you’re expecting. Look for lab and clinical studies exploring the peptide's impact on skin cells.

And yes, we’ve ensured these boxes are checked through lab and clinical tests before adding any of these peptides to our products:

Plant-Derived Bioactive Peptides

Extracted from the seeds of the moringa tree, these peptides help purify the skin, protecting it against environmental pollution. Particulate matter containing heavy metals like mercury and cadmium, found in atmospheric pollution, can accelerate skin aging, hyperpigmentation, eczema, psoriasis, acne, and even skin cancer.[8]Moringa Oleifera Seed Extract has long been used in traditional medicine and Ayurvedic practices. Now, it can be found in OS-01 EYE, helping to protect the thinner, delicate skin around the eyes from environmental pollutants that can trigger skin aging.

05

Peptides' Role in Skin Health

Peptides are superstars when it comes to skin health. Due to their size, they can often penetrate the skin barrier more effectively than growth factors, allowing their active benefits to be delivered more directly to the skin’s deeper layers.[6,7] Unlike growth factors, peptides represent an extremely broad range of molecules. Not all peptides are equal, and their activity within the skin, stability, and ability to penetrate the skin depends on the individual peptide used. It’s essential to make sure that the peptide:

Reaches the right skin layer to do its job. Look for penetration studies to ensure the peptide is penetrating to the dermis layer of skin.
Stays stable in its packaging. Look for stability testing on the peptide, especially at various temperatures.
Delivers the results you’re expecting. Look for lab and clinical studies exploring the peptide's impact on skin cells.

And yes, we’ve ensured these boxes are checked through lab and clinical tests before adding any of these peptides to our products:

Plant-Derived Bioactive Peptides

Extracted from the seeds of the moringa tree, these peptides help purify the skin, protecting it against environmental pollution. Particulate matter containing heavy metals like mercury and cadmium, found in atmospheric pollution, can accelerate skin aging, hyperpigmentation, eczema, psoriasis, acne, and even skin cancer.[8]Moringa Oleifera Seed Extract has long been used in traditional medicine and Ayurvedic practices. Now, it can be found in OS-01 EYE, helping to protect the thinner, delicate skin around the eyes from environmental pollutants that can trigger skin aging.

Argireline

Argireline, or Acetyl Hexapeptide-8, is a neurotransmitter-inhibitor peptide designed to reduce muscle activity in targeted areas of the face. By relaxing facial muscles, Argireline significantly reduces the appearance of expression lines and wrinkles, particularly when used around thinner skin like that around the eyes. This peptide is a non-invasive alternative to injectable treatments like Botox, offering visible results for dynamic wrinkles without the associated risks.[9,10] With Argireline included in OS-01 EYE, those expression wrinkles don’t stand a chance.

Argireline

Argireline, or Acetyl Hexapeptide-8, is a neurotransmitter-inhibitor peptide designed to reduce muscle activity in targeted areas of the face. By relaxing facial muscles, Argireline significantly reduces the appearance of expression lines and wrinkles, particularly when used around thinner skin like that around the eyes. This peptide is a non-invasive alternative to injectable treatments like Botox, offering visible results for dynamic wrinkles without the associated risks.[9,10] With Argireline included in OS-01 EYE, those expression wrinkles don’t stand a chance.

Biomimetic Vegan Collagen Peptide

While most topical collagen products fail to penetrate the skin barrier due to their large size, this bio-designed vegan collagen peptide goes deeper. What makes this peptide particularly unique is its ability to replicate the benefits of type 21 collagen—a rare but powerful form of collagen that accounts for less than 1% of the body’s collagen by adulthood. Despite its scarcity, type 21 plays a significant role as a signaling molecule, boosting essential components of the extracellular matrix, including elastin, laminin, collagen, and fibronectin.[11]We include this biomimetic vegan collagen peptide in OS-01 EYE as it helps signal your skin to produce those essential proteins that keep the skin around your eyes looking youthful. Plus, it’s vegan and cruelty-free!

Biomimetic Vegan Collagen Peptide

While most topical collagen products fail to penetrate the skin barrier due to their large size, this bio-designed vegan collagen peptide goes deeper. What makes this peptide particularly unique is its ability to replicate the benefits of type 21 collagen—a rare but powerful form of collagen that accounts for less than 1% of the body’s collagen by adulthood. Despite its scarcity, type 21 plays a significant role as a signaling molecule, boosting essential components of the extracellular matrix, including elastin, laminin, collagen, and fibronectin.[11]We include this biomimetic vegan collagen peptide in OS-01 EYE as it helps signal your skin to produce those essential proteins that keep the skin around your eyes looking youthful. Plus, it’s vegan and cruelty-free!

OS-01 Peptide

Developed and tested in the OneSkin lab, our OS-01 peptide represents a step forward in peptide technology. Built for skin longevity, the OS-01 peptide actively reduces the accumulation of senescent cells in the skin.[12,13] Senescent, or zombie cells, stop dividing but remain metabolically active, releasing harmful pro-inflammatory signals known as senescence-associated secretory phenotypes (SASP). These signals can induce neighboring healthy cells into senescence, accelerating skin aging. OS-01 works by promoting cellular repair, blocking SASP secretion from senescent cells, and reducing the overall senescent cell load in skin.[12] By preventing the buildup of senescent cells, OS-01 helps promote collagen production, reduces melanin production for reduced visible hyperpigmentation, and increases epidermal thickness, making your skin look, feel, and act like younger skin. [12, 13, 14] Put simply, the OS-01 peptide is the first peptide proven to reverse the biological age of skin.[13]

OS-01 Peptide

Developed and tested in the OneSkin lab, our OS-01 peptide represents a step forward in peptide technology. Built for skin longevity, the OS-01 peptide actively reduces the accumulation of senescent cells in the skin.[12,13] Senescent, or zombie cells, stop dividing but remain metabolically active, releasing harmful pro-inflammatory signals known as senescence-associated secretory phenotypes (SASP). These signals can induce neighboring healthy cells into senescence, accelerating skin aging. OS-01 works by promoting cellular repair, blocking SASP secretion from senescent cells, and reducing the overall senescent cell load in skin.[12] By preventing the buildup of senescent cells, OS-01 helps promote collagen production, reduces melanin production for reduced visible hyperpigmentation, and increases epidermal thickness, making your skin look, feel, and act like younger skin. [12, 13, 14] Put simply, the OS-01 peptide is the first peptide proven to reverse the biological age of skin.[13]

Related Products

OS-01 EYE Topical Supplement

- Subscription / $109 - One Time Purchase

999 reviews

Shop Now

Related Products

OS-01 EYE Topical Supplement

- Subscription / $109 - One Time Purchase

999 reviews

SHOP NOW

Key Takeaways:

Growth factors are potent proteins responsible for skin healing and collagen stimulation.
Due to their size, topical growth factors face penetration challenges, offering limited benefits without supplementary treatments.
By circumventing the epidermal barrier, injectable growth factors directly stimulate collagen and elastin production within the dermis.
The often small molecular size of peptides enables epidermal penetration, making them more effective for topical anti-aging therapies.
Peptides can stimulate collagen production, enhance skin elasticity, and can mimic Botox-like effects by inhibiting muscle contraction.
Not all peptides are created equal. Peptides represent a broad class of molecules, and consumers should, therefore, ensure that their penetration, stability, and efficacy have been thoroughly researched.

Key Takeaways:

Growth factors are potent proteins responsible for skin healing and collagen stimulation.
Due to their size, topical growth factors face penetration challenges, offering limited benefits without supplementary treatments.
By circumventing the epidermal barrier, injectable growth factors directly stimulate collagen and elastin production within the dermis.
The often small molecular size of peptides enables epidermal penetration, making them more effective for topical anti-aging therapies.
Peptides can stimulate collagen production, enhance skin elasticity, and can mimic Botox-like effects by inhibiting muscle contraction.
Not all peptides are created equal. Peptides represent a broad class of molecules, and consumers should, therefore, ensure that their penetration, stability, and efficacy have been thoroughly researched.

References

https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1372423
https://pubmed.ncbi.nlm.nih.gov/9558492/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333026/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952126/
https://pubmed.ncbi.nlm.nih.gov/33354795/
https://www.mdpi.com/2079-9284/10/4/111
https://ncbi.nlm.nih.gov/pmc/articles/PMC7023394/
https://cosmetotheque.com/wp-content/uploads/2021/05/PURISFOT-PW-PSE-LS9836-MKTG-5.pdf
https://pubmed.ncbi.nlm.nih.gov/23417317/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665711/
https://www.scconline.org/Portals/100/Geltor%20-%20343.pdf
Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.

References

https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1372423
https://pubmed.ncbi.nlm.nih.gov/9558492/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333026/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952126/
https://pubmed.ncbi.nlm.nih.gov/33354795/
https://www.mdpi.com/2079-9284/10/4/111
https://ncbi.nlm.nih.gov/pmc/articles/PMC7023394/
https://cosmetotheque.com/wp-content/uploads/2021/05/PURISFOT-PW-PSE-LS9836-MKTG-5.pdf
https://pubmed.ncbi.nlm.nih.gov/23417317/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665711/
https://www.scconline.org/Portals/100/Geltor%20-%20343.pdf
Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin

Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.

Discover More

How To Turn Your Skin Care Resolutions Into Skin C...

What Does Clean Beauty Mean, And Why Does Safe Bea...

Winter Skincare - How To Prevent Dry Skin this Sea...

What Are Chemical Peels & Are There Alternatives?

How Relationships, Community, & Social Interaction...

Hair Loss 101: Combing Through the Science of Hair...

Why Men Shouldn’t Ignore Skin Care: What’s Missing...

Navigating Skin Longevity: The Industry, The Scien...

What’s the Difference Between Dry and Dehydrated S...

How to Keep Your Hair Healthy and Strong During Pe...

What are Zombie Cells & How Can We Remove Them?

Collagen For Menopause: Why Is It Necessary For Healthy Skin Aging?

Collagen During Menopause: Is It Necessary For Hea...

Behind the Seal: How OneSkin Achieved the National...

Sun Sensitivity And Menopause: Protecting Your Cha...

Peptides Vs Growth Factors: Which is Better For Sk...

Hyperpigmentation and Menopause: Understanding and...

Skin Care is Health Care: Why Skin Care is the Key...

How Do Our Products Work Together?

The Connection Between Mental Health, Age Percepti...

OneSkin launches MolClock, the first skin-specific molecular clock to determine the biological age of human skin - One Skin Technologies

MolClock: Using Epigenetics to Measure The Biologi...

How OS-01 BODY Pauses Biological Aging For Overall...

Biohacking Healthy Aging: The Organs of Longevity

Does Niacinamide Help With Acne & Scarring?

5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...

6 Common In-Office Skin Treatments to Complement y...

What is Microneedling & Are There Alternatives?

How to Protect Against and Reverse Collagen Loss

Why Your Neck, Décolletage, and Hands Need Extra C...

What's the Connection Between Dehydration and Dry ...

How to Tighten Facial Skin Without Surgery

Exploring Alternatives to Botox

Best Practices for Moisturizing After Exfoliating

Recognizing Signs of Over-Exfoliated Skin

Healing Over-Exfoliated Skin: How to Treat Over-Ex...

OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...

Introducing OS-01 BODY SPF: Triple power protectio...

Is Talc Bad for Skin? 7 Things You Need to Know

How Do We Know the OS-01 Peptide is Safe?

What Is Lanolin and Is It Bad for Your Skin?

Non-Comedogenic vs Comedogenic Skin Care Products

Mineral Oil: Facts, Myths, and Effects on Skin

The Problem with Paraffin for Skin

Petrolatum: Is it Safe or Harmful for Your Skin?

How Much Sunscreen to Apply

What Do Antioxidants Do For Skin and Why Should Yo...

Making Sense of SPFs: What’s the Difference Betwee...

How to Relieve Itchy Skin: Tips for Soothing Skin ...

What is The Difference Between UVA and UVB Rays?

Decoding the Connections Between Intrinsic & Extri...

Causes of Skin Itching: Understanding the Reasons ...

How to Protect Your Skin from UVA and UVB Rays

Morning vs. Night Exfoliation: Determining the Bes...

How to Tell if Acne is Hormonal or Bacterial?

How to Know if Your Skin Barrier is Damaged

Tips for Managing Hormonal Breakouts

Understanding Hormonal Acne and Its Triggers

How to Repair & Restore Your Skin Barrier

How To Get Rid of Crepey Skin: 7 Solutions

When to Apply Sunscreen: Before or After Moisturiz...

How Alcohol Impacts Your Skin’s Health

The Effects of Alcohol on Your Skin's Aging Proces...

OS-01 FACE: Clinically Validated to Support Your S...

Can Alcohol Cause Breakouts?

The Proof is in the Peptide: 12-Week Clinical Stud...

Why Is My Neck Aging So Fast?

6 Factors That Contribute to Slow Skin Healing

6 Tips and Tricks for a Youthful Neck

Addressing the Need for Indoor Sun Protection

The Science of Sunburns: How to Treat and Prevent ...

Get to Know OneSkin’s Topical Supplements:
OS-01 F...

Can Air Quality Affect Skin? Exploring the Impact ...

Understanding the Relationship Between Sleep and U...

Exploring the Effects of Quality Sleep on Your Ski...

How to Improve Gut Microbiome

Exploring Caloric Restriction and Its Effects on A...

What’s the Connection Between Quality Sleep and Lo...

Unlocking the Skin Benefits of Intermittent Fastin...

Why Exercise is a Game-Changer for Longevity

The Microbiome Diet and Its Effects on Skin

Cold Exposure: Hype or Longevity Boosting?

Eat Better, Live Longer: Top Foods for Longevity

How to Protect Your Skin from Everyday Environment...

How Does Sunscreen Work? How Long Does it Last?

Pressing the Pause Button on Aging Skin: OS-01 BOD...

What Causes Dark Circles Under and Around Your Eye...

How to Brighten Eyes and Under-Eyes

Lip Balm Ingredients: What to Look for and What to...

Exploring Blue Zones: How Can We Optimize Our Heal...

Nurturing Your Lips: How to Keep Them Moisturized ...

Uncovering the 9 Causes of Dry Lips: Why Do Lips G...

How to Travel with Skin Care Products

Why is my Skin Peeling on My Face?

The Importance of Sunscreen: Why Should You Wear I...

Lip Sunscreen: Do Lips Need SPF Protection?

The Science of Gratitude

Removing Sunscreen: Tips for Clean and Healthy Ski...

Skin Explained: Is Skin An Organ?

UV Light and Skin: Effects and Protection Strategi...

Understanding The Epidermis: Functions, Compositio...

Diving into Dermis: Functions and Significance

Unlocking the Science of Wrinkles: Causes, Formati...

PREP enhances the effects of OS-01 FACE, and the p...

Why Skin Barrier is Important

Ingredient Spotlight: Bentonite Uses, Benefits, & ...

Hypodermis: Exploring Its Vital Functions

oil-dropper-background-pink-dripping-cosmetic-product

The EU is Limiting Retinol in Skincare: Here’s Eve...

Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...

Ceramides For Skin: Everything You Need to Know ne...

Age Gracefully: How to Manage Neck Wrinkles and Ac...

Discover Why Our New SPF Outperforms the Rest

How to Preserve Your Feet: 5 Strategies for Wrinkl...

Hands and Dermal Elasticity: Understanding and Man...

The Lip Lineage: Exploring the Why Behind Wrinkled...

How to Address Stomach Wrinkles For Smoother Skin

A Scientific Approach to Addressing Wrinkly Skin o...

What is Skin Cycling? Understanding, Embracing, an...

How to Skin Cycle: A Guide to Optimize Your Skin C...

Do You Know What Clinical Claims Really Mean?

What is Tinted Sunscreen?

2 Types of Wrinkles and Tips for Treating Them

Understanding Marionette Lines: Causes and Prevent...

How to Help Your Skin Act Younger

The Science of Sunscreen: Understanding the Optima...

Better Elasticity, More Firmness: Discover OS-01 E...

Symptoms and Causes of Melasma on Face

How to Prevent Skin Aging Before It Starts

A Comprehensive Guide to Understanding the Differe...

How to Strengthen Your Skin: A Guide to Thicker, H...

An In-Depth Look at Glycerin: What is it and What ...

Exploring the Benefits of Glycerin for Skin Health

Difference Between Hydrating and Moisturizing

Exploring the Difference Between Hydrating and Moi...

3 Natural Ways to Keep Your Skin Hydrated and Glow...

How To Create A Hydrating Skin Care Routine For Dr...

Senotherapeutics, Senolytics, and Senomorphics -- ...

Cleansing 101: How to Wash Your Face the Right Way...

Scientific Breakthrough: OneSkin’s scientists show...

Dry Skin 101: How To Identify This Skin Type

How OS-01 Can Help Your Collagen Levels As You Age...

Developing a Skin Care Routine for Normal Skin: 4 ...

What is Normal Skin & Do I Have This Skin Type?

A Step-by-Step Guide to Creating the Perfect Skin ...

Understanding Oily Skin: Causes & Characteristics

7 Keys to Understanding Menopause and Skin Changes

Is This The Root Cause of Aging?

UV Damage Increases Cellular Senescence. Here's Ho...

Our Research Has Been Published in npj Aging

How To Reduce Hyperpigmentation by Targeting Cellu...

Perfect Skin Care Routine for Combination Skin

4 Steps to Crafting the Perfect Skin Care Routine ...

A Comprehensive Guide to Understanding and Managin...

An In-Depth Look At The Benefits Of Moringa Oil Fo...

How to Tighten the Skin Under Your Eyes

7 Causes For Crepey Skin Under Eyes

101 Guide To Restoring Dry Skin Around The Eyes

How is OS-01 EYE different from OS-01 FACE?

How to Remove Lingering Dead Skin Cells On the Fac...

Safe Beauty, Validated: Why OneSkin trusts SkinSAF...

Hallmarks of Aging

What is Sensitive Skin?

How OS-01 Works on Mature Skin

Is Fragrance Bad for Your Skin?

Target Cellular Senescence with the Highest Concen...

Can a Plant-Based Diet Really Increase Your Health...

Eye Skin Ages Faster: Here’s How OS-01 Can Help

Gut Health and Skin: How Are They Connected?

The Science Behind Why The Skin Around the Eyes Ag...

How OS-01 EYE Supports the Ultra-Thin Skin Around ...

How Do You Know When to Stop Using Retinol?

How To Heal Skin From Picking Your Face Too Much

Collagen And Elastin: What Role Do They Play In Sk...

Why We Want Skin To Be More, Not Less

More Than Skin Deep: How Physical Touch Predicts L...

What is Skin Inflammation? What Causes it?

How to Reverse (or Prevent) Aging Skin

Yes, You Need Sunscreen During Winter

Can You Use Hyaluronic Acid with Retinol?

Exploring the skin’s purpose in whole-body health

Stressed Skin: 4 Stress Effects on the Skin

What Does Hyaluronic Acid Do For Your Skin?

Good Genes vs. Good Habits: Which Impacts Your Lon...

What Are The Causes Of Dry, Flaky Skin On Your Fac...

What is the Best Skin Care Regimen for Aging Skin?

7 Benefits of Jojoba Oil

What happens to skin as a person ages?

What are the Benefits of Sulforaphane?

8 Benefits of Andiroba Oil For Skin

Invasive vs. Non-Invasive Skincare: The pros and c...

Allantoin For Skin: A Comprehensive Guide

This is the Data to Look For When Choosing Skin Ca...

Why cellular senescence is more than just one of t...

A Simplified Guide To The Different Skin Texture T...

How OS-01 Works With Different Skin Types

How To Smooth Skin Texture On The Face: 4 Expert T...

Skin Microbiome: What It Is, Why it’s Important, A...

What Foods Cause Acne and Which Fight Against It?

The 101 Guide To Understanding Acne-Prone Skin

The Top 4 Prickly Pear Benefits for Skin

What Is Exfoliation & Is It A Necessary Measure Fo...

OneSkin Notable Mention: Dave Asprey's The Human U...

Retinol 101: Debunking Retinol as the Gold Standar...

Menopause & Skin: What you need to know

Take an Inside Look into Our Cutting-Edge R&D Plat...

101 Guide On The Benefits Of Cleansing Your Face

Cleanser Vs. Face Wash: Which Should I Reach For?

Five Common Skin Problems Experienced in Perimenop...

Get to Know OneSkin’s Topical Supplements:

OS-

...

The Top 3 Benefits of Peptides for Skin

How to Use Peptides In Your Skincare Regimen to Op...

Peptides vs Retinol: Is One Better For Increasing ...

What Is Causing the Uneven Skin Tone On Your Body?

How To Boost Skin Moisture For Your Entire Body Fr...

Three Ways To Extend Your Skinspan Starting With Y...

What Are Free Radicals and How Do They Impact Skin...

The Top 6 Best Antioxidants For Skin Health and Lo...

How OneSkin Developed the OS-01 Peptide

How chronic stress makes you age faster

What is Epidermal Thickness & Why Does it Matter?

Cell Turnover & Why It Slows As We Age

OneSkin Notable Mention: OneSkin Featured In Tony ...

101 Guide To Skin Tightening + 7 Noninvasive Metho...

Tight Feeling Skin: 3 Reasons Why

3 Skin Tightening Ingredients To Help Boost Skin H...

How to Reduce Skin Inflammation & Redness

Niacinamide Vs Retinol: How Do They Compare?

How to Incorporate OneSkin’s OS-01 Topical Supplem...

Why Is Nutrient Absorption Key To Better Skin Heal...

OneSkin Notable Mention: LifeSpan Episode 6 | The ...

The Top 10 Best Foods for Skin Repair

Are There Dangers of Retinol Cream Use?

What is Skin Elasticity & How Can You Improve It?

A Complete Guide to the 4 Stages of Wound Healing

4 Foods To Avoid During Wound Healing & Why

Celebrating Black History Month: A Discussion With...

What is the Function of Skin as a Protective Barri...

Representation of the Black Community in Skin Care...

Our Story: Learn more about the history of OneSkin...

What Is Senescence & Its Relationship To Aging?

Special Announcement: OneSkin to Donate 1% of Sale...

Biological Age: What is Biological Age, Why Does i...

What your skincare routine is missing (Hint. It’s ...

What is a peptide?
Peptides: the first piece of th...

Health Is The New Wealth

Sleep: Nature’s Restart Button? - One Skin Technologies

The Correlation Between Sleep and Skin: Why It Mat...

Calorie Restriction And Intermittent Fasting: Eati...

Healthspan: A New Way To Think About Aging