OUR SCIENCE
POWERED BY OS-01, the peptide proven to reverse skin aging
The first peptide proven to reverse skin’s biological age 01,02,03
by preventing the accumulation of senescent cells. 01,02
OUR SCIENCE
POWERED BY OS-01, the peptide proven to reverse skin aging
The first peptide proven to reverse skin’s biological age 01,02,03
by preventing the accumulation of senescent cells. 01,02
HOW OS-01 WORKS
HOW OS-01 WORKS
senescent cells
Cellular senescence is a root cause of aging.
Over time and with increasing environmental exposure, your cells experience DNA damage. As this damage accumulates, they enter a state of dysfunction called senescence.
Often called “zombie cells,” senescent cells secrete pro-aging factors that drive healthy neighboring cells to age faster and become senescent as well. As more cells become “infected”, the body experiences:
01
Increased Inflammation
02
Suppressed Immune Function
03
Increased Expression of Pro-Aging Genes
LEARN MORE ABOUT HOW CELLULAR SENESCENCE IS CENTRAL TO AGING
senescent cells
HEALTHY CELLS
(BLUE)SENESCENT CELLS (GREY)
Cellular senescence is a root cause of aging.
Over time and with increasing environmental exposure, your cells experience DNA damage. As this damage accumulates, they enter a state of dysfunction called senescence.
Often called “zombie cells,” senescent cells secrete pro-aging factors that drive healthy neighboring cells to age faster and become senescent as well. As more cells become “infected”, the body experiences:
01
Increased Inflammation
02
Suppressed Immune Function
03
Increased Expression of Pro-Aging Genes
LEARN MORE ABOUT HOW CELLULAR SENESCENCE IS CENTRAL TO AGING
The more senescent cells you have, the older your skin acts.
As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.
01
Reduced production of collagen, elastin, and hyaluronic acid
02
Decreased epidermal thickness
03
Compromised barrier function
04
Decreased elasticity & strength
The more senescent cells you have, the older your skin acts.
As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.
01
Reduced production of collagen, elastin, and hyaluronic acid
02
Decreased epidermal thickness
03
Compromised barrier function
04
Decreased elasticity & strength
By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies” – containing the spread of senescence and slowing down skin aging.
By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies” – containing the spread of senescence and slowing down skin aging.
meet os-01
Reduce cellular senescence in your skin with OS-01
Our breakthrough OS-01 peptide boosts DNA damage repair in senescent cells, preventing them from secreting pro-aging factors.01,02 This effectively stops the spread of senescence and reduces your skin’s biological age at the cellular level.01,02,03
The result? Healthier skin that looks, feels, and acts like younger skin for longer. 01,02,04
EXPLORE THE DATA
meet os-01
Reduce cellular senescence in your skin with OS-01
Our breakthrough OS-01 peptide boosts DNA damage repair in senescent cells, preventing them from secreting pro-aging factors.01,02 This effectively stops the spread of senescence and reduces your skin’s biological age at the cellular level.01,02,03
The result? Healthier skin that looks, feels, and acts like younger skin for longer. 01,02,04
EXPLORE THE DATA
01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at
oneskin.co/claims 02
Zonari, A., et al. npj Aging, 202303
Boroni, M. et al. Clinical Epigenetics, 202004
Zonari, A., et al. Journal of Cosmetic Dermatology, 202401 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at
oneskin.co/claims 02
Zonari, A., et al. npj Aging, 202303
Boroni, M. et al. Clinical Epigenetics, 202004
Zonari, A., et al. Journal of Cosmetic Dermatology, 2024