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NEW LIMITED EDITION SETS

Here for the holidays.

Built for the long game.

Introducing curated sets for every skincare journey, with skin longevity benefits that last long after the season ends.

Shop now
OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in white and 'PEPTIDE' in bold white letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age1.

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

The real proof? It’s in the numbers.

10+
Years of Research
900+
Peptides Screened
22+
Patents & Publications
15000+
5-Star Reviews
A white cylindrical bottle labeled ONE SKIN stands on a black surface in a clean studio setup. A gloved hand and laboratory tools, including a microscope, ring lights, and stacked test tubes, are arranged around it against a light gray background.

OUR APPROACH

Led by science, not hype.

icon of a lab flask

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

Icon of a vial

Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Icon of a piece of paper with a circled check mark in the foreground

Ongoing clinical studies

Conducted by independent, third-party research organizations.

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Peer-reviewed publications

The gold standard for scientific research and in skincare.

Citations

  1. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)
  2. Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
  3. Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
  4. Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
  5. Zonari, A., et al. OS-01 Peptide Topical Formulation Improves Skin Barrier Function and Reduces Systemic Inflammation Markers: A Pilot 12-Week Clinical Trial. J Cosmet Dermatol. 2025; 24: e70169. doi: 10.1111/jocd.70169