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A woman in a white lab coat and black gloves holds a pipette in a laboratory setting with shelves of bottles in the background.
A woman with long brown hair wearing a white lab coat looks to the side in a laboratory setting with shelves of bottles and containers blurred in the background.

Born in our lab.

Built for longevity.

Skincare powered by our proprietary OS-01 Peptide™ to target aging where it begins—at the cellular level.

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OS-01 Peptide logo featuring a solid orange square on the left, followed by the text 'OS-01' in white and 'PEPTIDE' in bold white letters, with a small trademark symbol.

Engineered to reverse skin’s visible biological age1.

Built on over a decade of longevity science, our proprietary OS-01 Peptide™ reverses the visible effects of senescent (dysfunctional) cells that degrade collagen, elastin, hyaluronic acid and barrier strength. The result: skin that looks, feels, and acts younger over time.

The real proof? It’s in the numbers.

10+
Years of Research
900+
Peptides Screened
22+
Patents & Publications
15000+
5-Star Reviews
A white cylindrical bottle labeled ONE SKIN stands on a black surface in a clean studio setup. A gloved hand and laboratory tools, including a microscope, ring lights, and stacked test tubes, are arranged around it against a light gray background.

OUR APPROACH

Led by science, not hype.

icon of a lab flask

Rigorous R&D platform

End-to-end product development run by our in-house team of scientists.

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Scientifically validated claims

Quantified by our proprietary MolClock and Skin Age Modeling methods.

Icon of a piece of paper with a circled check mark in the foreground

Ongoing clinical studies

Conducted by independent, third-party research organizations.

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Peer-reviewed publications

The gold standard for scientific research and in skincare.

Citations

  1. Visible biological age defined as signs of aging such as smoothness and barrier strength. Based on a double-blind, third-party 12-week clinical study with 22 participants aged 54–65. (Zonari, A., et al. Journal of Cosmetic Dermatology, 2024.)
  2. Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
  3. Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
  4. Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
  5. Zonari, A., et al. OS-01 Peptide Topical Formulation Improves Skin Barrier Function and Reduces Systemic Inflammation Markers: A Pilot 12-Week Clinical Trial. J Cosmet Dermatol. 2025; 24: e70169. doi: 10.1111/jocd.70169