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Best Sellers Bundle

Name: Best Sellers Bundle
Brand: OneSkin
Price: 199.0 USD
Availability: InStock
Rating: 4.7 (3776 reviews)

OS-01 FACE + OS-01 EYE

4.7 (3776)

One-Time purchase - $199.00

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Quantity

Best Sellers Bundle

$183.00 ~~$229.00~~

Try it risk-free! 45 day money back guarantee.

Format Rich eye cream + lightweight moisturizer
Targets Dehydration, loss of elasticity, dullness, wrinkles
Suited to All skin types, safe for sensitive skin

Best Sellers Bundle includes:

Description

Target cellular aging on the skin that’s most exposed to the environment, including the face, neck, and ultra-delicate area around the eyes. This duo works together to target a root cause of skin aging, reducing the visible signs of aging and improving barrier function^01,02,03

Clean + Safe Ingredients

Benefits

Multitasking moisturizer and concentrated eye cream duo that target the most common signs of aging

Wrinkle reduction

Boosts collagen to visibly smooth lines and wrinkles.^01,02,04

Hydration

Improves barrier function, allowing your skin retain moisture and stay hydrated.^01,02

Firmness

Supports skin health for a firmer, more lifted appearance.^01,02

OS-01 FACE

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

OS-01 EYE

See why customers love OS-01 EYE

“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.

"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.

"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.

"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.

The science behind the Best Sellers Bundle

With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:

01 Increases epidermal thickness ⁰³

02 Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) ^03,04

03 Promotes cellular proliferation (increase in MKI67) ⁰³

Learn more

^{Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE}

The skin around the eyes is among the thinnest on the body,⁰⁵ making it exceptionally delicate and prone to aging. This vulnerability leads to higher levels of cellular senescence,⁰⁶ leaving the eye area more susceptible to sagging and wrinkles.

OS-01 EYE was specifically designed to address the unique needs of this fragile skin, delivering the highest concentration of our OS-01 peptide for unparalleled skin health benefits.

In lab studies, our scientists analyzed key aging biomarkers in human skin samples before and after treatment. Their findings show that OS-01 EYE:

01 Promotes collagen biosynthesis (increase in COL1A1) and retention (decrease in MMP1) ⁰⁴

02 Reduces a key biomarker associated with cellular senescence (CDKN2A) ⁰⁴

03 Lowers a key biomarker linked to inflammation (IL-8) ⁰⁴

Learn more

^{Shown in lab studies on ex vivo human eyelid skin samples by analyzing levels of collagen in skin treated with OS-01 EYE compared to no treatment. Skin treated with OS-01 EYE displayed a significant increase compared to skin with no treatment.}

Active ingredients that complement the OS-01 peptide

See all ingredients

Pracaxi Oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
Andiroba Oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
Oleic Pau Mulato Extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin.
Hyaluronic Acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
Moringa Oleifera Seed Extract
Extracted from the seeds of the Moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
Fucus Vesiculosus Algae Extract
This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
Biomimetic Vegan Collagen
This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.

OS-01 FACE

Pracaxi Oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
Andiroba Oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
Oleic Pau Mulato Extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin.
Hyaluronic Acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.

OS-01 EYE

How to apply OS-01 EYE

Follow these easy steps for optimal results

Dispense 1 pump onto tip of finger.
Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone.
Use 2 times daily.

OS-01 FACE

How to apply OS-01 FACE

Follow these easy steps for optimal results

Dispense 1-2 pumps onto fingers.
Gently massage into skin on the face and neck.
Use 2 times daily.

How it works

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level. ^03,07

about the science

All Ingredients

OS-01 FACE:
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

OS-01 EYE:
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.

Citations

⁰¹Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

⁰² Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042

⁰³ Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

⁰⁴ Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

⁰⁵ New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112

⁰⁶ Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x

⁰⁷ Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

Best Sellers Bundle

4.7

Rated 4.7 out of 5 stars

Based on 3,776 reviews

Total 5 star reviews: 3.2k Total 4 star reviews: 388 Total 3 star reviews: 130 Total 2 star reviews: 42 Total 1 star reviews: 51

94%would recommend these products

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3,776 reviews

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CM
Candace M.
Verified Buyer
Reviewing
OS-01 EYE Topical Supplement Refill
I recommend this product
Rated 5 out of 5 stars
3 hours ago
Noticeable results in a few weeks
I was pleasantly surprised to see how quickly small lines and discoloration around my eyes cleared up when I started using the Eye topical supplement. Such a tiny bit of product made such a big difference!
Was this helpful?
RE
Randy E.
Verified Buyer
Reviewing
Best Sellers Bundle
I recommend this product
Rated 5 out of 5 stars
3 hours ago
Really high quality
Great products. Had to order another face wash bottle, because the face wash that came in the bundle is the refill.
Was this helpful?
MS
Monica S.
Verified Buyer
Reviewing
OS-01 FACE Refill Pouch
I recommend this product
Rated 5 out of 5 stars
4 hours ago
Fabulous!
I have been using for the last 6 months and I love One Skin. I use it every night as part of my skincare routine and to support my body in removing senescent cells and my bodies evening repair. It's light and I apply it first before going in with the rest of my regime.
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RD
Rae-Ann D.
Verified Buyer
Reviewing
OS-01 FACE Refill Pouch
I recommend this product
Rated 5 out of 5 stars
7 hours ago
Great
Worked well, haven’t had issues with refills not pumping. Like the option to replace the empty pouch
Was this helpful?
AS
Andrea S.
Verified Buyer
Reviewing
Best Sellers Bundle
I recommend this product
Rated 5 out of 5 stars
23 hours ago
Best Skin Care Ever
The One Skin Best Sellers Bundle is hands down one of the best skincare investments I’ve made. Every product in the bundle works beautifully together to improve skin health, tone, and texture. The cleanser is gentle yet effective, the OS-01 serum is a game changer—it leaves my skin noticeably smoother, more hydrated, and radiant—and the moisturizer locks everything in without feeling heavy or greasy. After just a few weeks, I’ve received compliments on how glowing and healthy my skin looks. It’s clear that these products are backed by serious science. If you’re looking to streamline your skincare routine with high-performance essentials, this bundle is a must-have!
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All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

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