Best Sellers Bundle
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- Format Rich eye cream + lightweight moisturizer
- Targets Dehydration, loss of elasticity, dullness, wrinkles
- Suited to All skin types, safe for sensitive skin
Benefits
Multitasking moisturizer and concentrated eye cream duo that target the most common signs of aging
Wrinkle reduction
Boosts collagen to visibly smooth lines and wrinkles.01,02,04
Hydration
Improves barrier function, allowing your skin retain moisture and stay hydrated.01,02
Firmness
Supports skin health for a firmer, more lifted appearance.01,02
OS-01 FACE
See why customers love OS-01 FACE
“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.
"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.
OS-01 EYE
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
The science behind the Best Sellers Bundle
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
01 Increases epidermal thickness 03
02 Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 03,04
03 Promotes cellular proliferation (increase in MKI67) 03
Active ingredients that complement the OS-01 peptide
-
- Pracaxi Oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties. - Andiroba Oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation. - Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer. - Oleic Pau Mulato Extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing. - Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin. - Hyaluronic Acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
- Pracaxi Oil
- Pracaxi Oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties. - Andiroba Oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation. - Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer. - Oleic Pau Mulato Extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing. - Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin. - Hyaluronic Acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
OS-01 EYE
How to apply OS-01 EYE
Follow these easy steps for optimal results
- Dispense 1 pump onto tip of finger.
- Gently tap in a semi-circle around each eye, from the under eye to the eyelid and underneath the brow bone.
- Use 2 times daily.
OS-01 FACE
How to apply OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers.
- Gently massage into skin on the face and neck.
- Use 2 times daily.
How it works
Powered by the OS-01 Senescence Peptide™
The only peptide scientifically proven to reverse skin aging at the cellular level. 03,07
All Ingredients
OS-01 FACE:
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
OS-01 EYE:
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
Citations
01Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
02 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
03 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
04 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
05 New biological insights into skin aging around the eye. Journal of the American Academy of Dermatology, Volume 74, Issue 5, AB28 https://doi.org/10.1016/j.jaad.2016.02.112
06 Tagami, H. (2008), Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. International Journal of Cosmetic Science, 30: 413-434. https://doi.org/10.1111/j.1468-2494.2008.00459.x
07 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
Best Sellers Bundle
- Angela R.Verified BuyerReviewingOS-01 EYE RefillI recommend this productRated 5 out of 5 starsBest product for eyes, neck and hands
The One skin EYE cream is the most effective wrinkle reducer I have ever tried. I use this product around and on my upper lids, my neck and the back of each hand. I have been using this product for 8 months and love it. Where I notice the most youthful collagen building effect is on my hands and the corners of my eyes.
- GinaReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars5 Stars
Love the feel and the results!
- Carol J.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 starsOS-01
Excellent product! Been using for over 2 years.
- RebeccaReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 stars5 Stars
As always, a wonderful product.
I hsve used the OneSkin FACE for 18 months and it protects, heals and nouishes my skin. I notice subtle fading in my dark spots (from childhood sun damage).
Thank you for a solid, real, simple, authentic skin care line.
- Zara M.Verified BuyerReviewingOS-01 FACE Refill PouchRated 3 out of 5 starsWonderful technology - tricky consistency
The technology behind this product is fantastic, which is why I continue to use it diligently. However, I do struggle with the consistency of the formulation. It’s difficult to layer with a serum, or a sunscreen due to pilling. I would like to see Oneskin create a pared back version of the OS-01 peptide which can be easily layered with other products. I’m not fussed about any other potential ingredients or secondary benefits - it’s the amazing OS-01 peptide I’m after!
OneSkin11 hours agoThank you for the feedback, Zara! We'd love to chat more about your routine and provide guidance on the right layering order. Feel free to email us at support@oneskin.co if you're interested. Additionally, if it's still not a fit, we offer a 45-day money-back guarantee. Your feedback is valuable, and we're here to assist in any way we can!
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886
