Face

OS-01 FACE Topical Supplement Refill

Name: OS-01 FACE Topical Supplement Refill
Brand: OneSkin
Price: 117.0 USD
Availability: InStock
Rating: 4.7 (5539 reviews)

4.7 (5539)

Starter Kit Refill

$117.00

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Quantity

OS-01 FACE Topical Supplement Refill

Try it risk-free! 45 day money back guarantee.

Suited to All skin types, safe for sensitive skin
Targets Dehydration, dullness, loss of elasticity
Format Lightweight moisturizer

Description

**Reusable plastic shell not included**

The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

Clean + Safe Ingredients

Benefits

Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment

Hydration

Boosts barrier function, allowing your skin retain moisture and stay hydrated.⁰²

Firmness

Switches off the cells that degrade collagen, helping skin stay firm.^01,03

Radiance

Enhances skin tone and texture, helping skin look and feel smooth and radiant.⁰²

5-STAR REVIEWS

See why customers love OS-01 FACE

“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.

"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.

"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.

"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.

The proof is in the pictures

CLINICAL DATA

Visible results, scientifically validated

100

of participants had improved smoothness ⁰²

95.5

of participants had improved firmness, radiance, and tone ⁰²

90

of participants had improved elasticity ⁰²

86

of participants had improved appearance of fine lines and wrinkles ⁰²

The Science Behind OS-01 FACE

With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:

Increases epidermal thickness ⁰¹
Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) ^01,03
Promotes cellular proliferation (increase in MKI67) ⁰¹

Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE

6 active ingredients that complement the OS-01 peptide

see all ingredients

Pracaxi Oil

Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.

Andiroba Oil

A seed oil that promotes healthy collagen and minimizes the effects of inflammation.

Niacinamide

A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.

Oleic Pau Mulato Extract

An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.

Allantoin

A skin-conditioning molecule that moisturizes and soothes irritated skin.

Hyaluronic Acid

A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.

Getting started with OS-01 FACE

Follow these easy steps for optimal results

Dispense 1-2 pumps onto fingers
Gently massage into skin on the face and neck
Use 2 times daily

How it works

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level ^01,02,03

Discover the Science

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

⁰¹ Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

⁰² Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242

⁰³ Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims