Benefits
Everything you need to cleanse, hydrate, nourish, and protect your skin in one routine
Radiance
PREP gently exfoliates to slough away dullness and reveal brighter, healthier-looking skin for enhanced absorption from the rest of your routine.01
Hydration
Topical supplements strengthen the skin barrier, allowing for better moisture retention and hydration.01,02,03
UV protection
OS-01 FACE SPF protects skin from UV damage, free radicals, and the effects of past aging.01
OS-01 FACE
See why customers love OS-01 FACE
“I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth…and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.” – Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" – Laura E.
"It’s working great!!! It absorbs quickly. I see and feel a significant difference in my skin’s texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." – Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." – Sarah B.
OS-01 EYE
See why customers love OS-01 EYE
“The concentration of peptides in this product has made a difference, especially to the circles under my eyes. I haven’t needed to use concealer since beginning to use this product. The science behind this product is solid.” – Kathy L.
"I've tried all sorts of different eye creams; the best out there. I have a very thin skin around my eyes with many expression lines and wrinkles and this product has been the most efficient in minimizing them and nourishing my skin. I all using this day and night very religiously and have no intention of ever stopping." – Archontia T.
"I simply love One Skin OS-01 Eye cream. It is silky smooth, absorbs efficiently, and never feels heavy or greasy. I have noticed the fine lines under my eyes and early crows feet slowly vanishing. It's subtle but evident the more I use it. This is the best product I have ever tried." – Bridgette G.
"OS-01 EYE is fantastic. I wish I had taken pictures when I started using this a year ago. I'm certain my eyes look better now than they did before. It absorbs immediately and yet is there moisturizing the area around my eyes all day long. It even smooths out the rough bumps around my eyes. This is a wonderful product. I love it!" – Donna G.
OS-01 BODY
See why customers love OS-01 BODY
“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.
"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.
"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.
Behind One Skin Longevity Science
As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.
- Possible Increase of Skin’s Epidermal Thickness
- Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
- May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
- Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.
-
6 active ingredients complement the OS-01 peptide
Pracaxi oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.Andiroba oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation.Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.Oleic Pau Mulato extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin.Hyaluronic acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
6 active ingredients complement the OS-01 peptide
Pracaxi oil
Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
Andiroba oil
A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
Niacinamide
A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
Oleic Pau Mulato extract
An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
Allantoin
A skin-conditioning molecule that moisturizes and soothes irritated skin.
Hyaluronic acid
A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
How it works
Powered by the OS-01 Senescence Peptide™
The only peptide scientifically proven to reverse skin aging at the cellular level 04,05
All Ingredients
OS-01 FACE:
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
OS-01 BODY:
Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide
OS-01 EYE:
Water, Glycerin, Sorbitan Olivate, Squalane, Cetearyl Olivate, Butyrospermum Parkii (Shea) Butter, Simmondsia Chinensis (Jojoba) Seed Oil, Cystoseira Humilis Extract, d-Panthenol, Bentonite, Cetyl Palmitate, Sodium Hyaluronate Crosspolymer, Caprylhydroxamic Acid, Sorbitan Palmitate, Cellulose, Coffea Arabica (Coffee) Seedcake Extract, Allantoin, Fucus Vesiculosus Extract, Gluconolactone, Niacinamide, sh-Polypeptide-121, Sisymbrium Irio Seed Oil, Tocopheryl Acetate, Sorbic Acid, Caprylic/Capric Triglyceride, Ubiquinone, Lecithin, Decapeptide-52*, Sodium Chloride, Maltodextrin, Acetyl Hexapeptide-8, Moringa Oleifera Seed Extract, Glyceryl Caprylate, Caprylyl Glycol, Tetrasodium Glutamate Diacetate, Alcohol, Sodium Benzoate, Phenoxyethanol, Xanthan Gum. *OS-01 Peptide.
PREP:
Water, Sodium Laurylglucosides Hydroxypropylsulfonate, Cocamidopropyl Hydroxysultaine, Disodium Lauryl Sulfosuccinate, Glycerin, Sodium Hydroxypropylphosphate Laurylglucoside Crosspolymer, Sodium Grapeseed Amidopropyl PG-Dimonium Chloride Phosphate, Hydrolyzed Opuntia Ficus-Indica Flower Extract, Breu Branco Resin, Caprylyl Glycol, Phenoxyethanol, Lonicera Japonica (Honeysuckle) Flower Extract, Niacinamide, Sorbic Acid, Arnica Montana (Arnica Flower) Extract, Tetrasodium Glutamate Diacetate
Citations
01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Zonari, A., et al. Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. Int J Cosmet Sci. 2025; 00: 1–11. doi:10.1111/ics.13042
04 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
05 Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1
OneSkin Travel Kit
- Angel H.Verified BuyerReviewingOneSkin Travel Kit CoralI recommend this productRated 4 out of 5 starsPerfect sampler
I bought this travel kit to sample the products. I am very sensitive and didn’t want to buy a lot and not be able to use it. I have loved it all. I already ordered a large bottle of the body lotion. Now I will have to buy a new travel kit to take with me.
OneSkin14 seconds agoHi Angel!
Thank you for reaching out! We are happy to hear you are enjoying the OneSkin Travel Kit!
- Ali S.Verified BuyerReviewingOneSkin Travel Kit TealI recommend this productRated 5 out of 5 starsOneSkin Travel Kit exceeds expectations
When the kit arrived, I was surprised by the generous size - it will replace previous travel kits on my next travels. The moisture-proof material is essential, and I love that the bag is somewhat pliable, it will be easy to fit in a crowded suitcase. I love the visibility (bright green in my case), and the travel-size bottles are a very nice size. This was a wonderful purchase!
- Jenny W.Verified BuyerReviewingOneSkin Travel Kit TealI recommend this productRated 5 out of 5 starsTravel Kit
Love the beautiful well made pouch and the travel kit is perfect! Will purchase again. Thank you
- Antonio F.Verified BuyerReviewingOneSkin Travel Kit BlackI recommend this productRated 5 out of 5 stars.
.
OneSkin1 week agoHi Antonio!
Thank you for the review! We are happy to hear you are enjoying your OneSkin Travel Kit!
- Kristi S.Verified BuyerReviewingOneSkin Travel Kit TealI recommend this productRated 5 out of 5 starsNew skin!
After only a few days I can see so many results! My skin feels smooth , less dry and brighter. Loving the product.
