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OS-01 HAIR peptide scalp serum

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$166.00

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$311.00

Include dermaroller?

We recommend at least 3-6 months of consistent use to see results.

Try it risk-free!Β 45 day money back guarantee.

A breakthrough for thicker, denser, healthier hair.01 Introducing the first scalp serum powered by OS-01, proven to target cellular senescence02, a biological process linked to hair loss and thinning.03-08

OneSkin

BENEFITS

Daily serum designed to nourish the scalp and reactivate your hair’s natural growth cycle01

Prevent a root cause of hair thinning

Prevents the accumulation of the cells that contribute to a disrupted hair growth cycle due to age, stress, and genetics.03-09

Scalp health

Safe for sensitive skin and promotes a healthy scalp microbiome, which can help foster healthy follicle function and hair density.01,09

Thicker, denser, fuller hair

Key ingredients complement the OS-01 peptide to promote strong, healthy hair.01

CLINICAL DATA

Visible results, scientifically validated

86.67

of participants showed an increase in hair density (average +39.62%) after 6 months 01

83.33

participants showed an increase in hair thickness (average +42.58%) after 6 months 01

80

Β of participants observed overall improvements in their hair after 3 months 01

76.67

of participants said the overall health of their hair improved after 6 months 01

5-STAR REVIEWS

See why customers love OS-01 HAIR

"Just fantastic regrowth in areas where I desperately needed it." β€”Β LaDonna L., Beta Tester

"It worked so well! No irritation and dried without leaving a residue." β€” Jodi F., Beta Tester

"This is a real solution. Others promise. This delivers. I can only imaging what I'd have to pay to have this in my daily routineβ€”and yes, I will pay it. After a certain age, you pay what you mustβ€”not to look younger, but to look your best." β€” Queen E., Beta Tester

What makes OS-01 HAIR unique?

  • Proprietary ingredient
  • No harsh side effects
  • Lightweight & non-greasy
  • Drug-free
  • No prescription
  • Supports scalp health
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OneSkin

The science behind OS-01 HAIR

Emerging research shows that senescence in hair follicles is linked to age-related thinning, stress-induced thinning, and pattern balding. 03-08

New research also shows that reducing senescent cells in hair follicles can stimulate regeneration.10,11 That's how our OS-01 peptide, proven to decrease cellular senescence in both hair and skin models, targets hair loss and thinning at its source.02,09

To test OS-01 HAIR’s ability to address senescence, our scientists treated senescence-induced cells with OS-01 HAIR. The results showed significantly reduced senescence levels, making OS-01 HAIR a promising candidate for addressing a key biological process linked to hair thinning and loss.03-09

Getting started with OS-01 HAIR

Follow these easy steps for optimal results

  • Apply 1 mL of serum (approximately 2 full droppers) directly to your scalp and massage in with fingertips
  • Leave on, do not rinse
  • Use up to 2 times daily

HOW IT WORKS

Powered by the OS-01 Senescence Blocking Peptideβ„’

The first and only peptide scientifically proven to target cellular senescence02,09, a biological process linked to hair loss and thinning.03-08

All Ingredients

Water, Glycerin, 1,2-Hexanediol, Butylene Glycol, Hydroxyacetophenone, Panthenol, Inulin, Helianthus Annuus (Sunflower) Sprout Extract, Cellulose Gum, Alpha-Glucan Oligosaccharide, Tetrasodium Glutamate Diacetate, Propanediol, Morus Nigra Leaf Extract, Arginine, Acetyl Tyrosine, Rehmannia Chinensis Root Extract, Pentylene Glycol, Sodium PCA, Erythritol, Chondrus Crispus, PEG-12 Dimethicone, Oryza Sativa (Rice) Bran, Decapeptide-52*, Calcium Pantothenate, Zinc Gluconate, Sodium Benzoate, Niacinamide, Ornithine HCL, Caprylyl Glycol, Polyquaternium-11, Citrulline, Hydrolyzed Soy Protein, Xanthan Gum, Glucosamine HCL, Disodium Succinate, Fisetin, Raspberry Ketone, Sodium Benzoate, Citric Acid, Potassium Sorbate, Arctium Majus Root Extract, Panax Ginseng Root Extract, Biotin. *OS-01 Peptide.

Citations

01 Shown in 6 month double-blind, independent, third-party clinical study with 30 participants using OS-01 HAIR and dermaroller daily. Results based on self-perception reporting and clinical measurements of anagen hairs per cm2, intermediate terminal hairs, hair shaft thickness, inter follicular mean distance, hair count per cm2, and scalp microbiome.

02 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β  and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03 Mirmirani, Paradi., et al. Age-related hair changes in men: Mechanisms and management of alopecia and graying. Maturitas, 80(1), 58 - 62. 2015.https://www.sciencedirect.com/science/article/abs/pii/S0378512214003259

04 Shin, Wisoo et al. Dysfunction of Hair Follicle Mesenchymal Progenitors Contributes to Age-Associated Hair Loss. Developmental Cell, 53(2), 185 - 198. 2020https://www.sciencedirect.com/science/article/pii/S1534580720302318

05 Huang, Wen-Yen., et al. Stress-induced premature senescence of dermal papilla cells compromises hair follicle epithelial-mesenchymal interaction. Journal of Dermatological Science, 86(2), 114 - 122. 2017
https://www.sciencedirect.com/science/article/abs/pii/S0923181117300269Β 

06 Lee, Sunhyoung et al. Ganoderma lucidum extract attenuates corticotropin-releasing hormone-induced cellular senescence in human hair follicle cells. iScience 27(5), 2024https://pmc.ncbi.nlm.nih.gov/articles/PMC11068553/

07 Lingna Chen, Y.M.Y.F., et al. Cellular senescence: ageing and androgenetic alopecia. Dermatology, 239, 533-541. 2023.
https://karger.com/drm/article/239/4/533/836627/Cellular-Senescence-Ageing-and-AndrogeneticΒ 

08Bahta, Adiam W., et al. Premature Senescence of Balding Dermal Papilla Cells In Vitro Is Associated with p16INK4a Expression. Journal of Investigative Dermatology, 128(5), 1088 - 1094.2008.
https://www.jidonline.org/article/S0022-202X(15)33852-5/fulltextΒ 

09 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

10 Pappalardo, Alberto., et al. Restoration of hair follicle inductive properties by depletion of senescent cells. Aging cell, 24(1). 2025.
https://pubmed.ncbi.nlm.nih.gov/39614601/Β 

11 Baar, Marjolein P et al. Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging. Cell, 169(1), 132-147. 2017.
https://pmc.ncbi.nlm.nih.gov/articles/PMC5556182/Β Β 

12 Shown in a 3 month beta test (brand led consumer perception study) with 22 participants and daily application of OS-01 HAIR (no dermaroller).

OS-01 HAIR peptide scalp serum

4.4
Rated 4.4 out of 5 stars
Based on 10 reviews
Total 5 star reviews: 7 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 1
90%would recommend these products
Rating
Ratings
10 reviews
  • HOLLY S.
    Verified Buyer
    Reviewing
    OS-01 HAIR 6 month delivery / Yes +$10
    I do not recommend this product
    Rated 1 out of 5 stars
    It is too early for results… but my hair is so flat and difficult to style

    Sadly I have been considering returning the product because my hair is flat and difficult to style with this product on my scalp. I am not using a ton of it… Not even one dropper full. Have others had this problem?

    OneSkin
    2 days ago

    Thank you for the feedback, Holly! We'd love to chat more about your routine and provide guidance on the right layering order. Feel free to email us at support@oneskin.co if you're interested. Additionally, if it's still not a fit, we offer a 45-day money-back guarantee. Your feedback is valuable, and we're here to assist in any way we can!

  • Melissa M.
    Verified Buyer
    Reviewing
    OS-01 HAIR
    I recommend this product
    Rated 5 out of 5 stars
    Amazing product!

    Doesn’t leave my hair greasy or messed up. Calms my scalp.

  • Jonathan E.
    Verified Buyer
    Reviewing
    OS-01 HAIR 3 month delivery / Yes +$10
    I recommend this product
    Rated 5 out of 5 stars
    Great product

    I’ve been using this for a month with my regular hair growth products and they are supercharged with this. I’ve been using your facial products for almost a year, and in my entire life I’ve never received compliments for my skin, and now I get them constantly. People can’t believe I’m in my 50s. I tested it before and after, or you can also see how good my skin looks now. Not the thickness in my forehead hair wise. The first picture is from 2023, the second picture I just took today.

    OneSkin
    2 weeks ago

    Hi Jonathan,

    Thank you for the review! We are happy to hear you are enjoying OS-01 HAIR!

  • Kim E.
    Verified Buyer
    Reviewing
    OS-01 HAIR 3 month delivery / Yes +$10
    I recommend this product
    Rated 4 out of 5 stars
    The product goes on nicely and not greasy

    I think it hasn’t been long enough for me to notice a difference yet but looking forward to great results!

    OneSkin
    2 weeks ago

    Hi Kim!

    Thank you for the review! We are happy to hear you are enjoying OS-01 HAIR!

  • Lauren I.
    Verified Buyer
    Reviewing
    OS-01 HAIR 3 month delivery / Yes +$10
    I recommend this product
    Rated 4 out of 5 stars
    So far, so much better than others on the market

    I'm fresh off almost a year of no results from the cult favorite Harklinikken, so I can't help but compare the two. While I've only been using OS-01 for a few weeks, I already prefer it. I love the simplicity of use and the lack of auxiliary products (other than the optional dermaroller, which I did purchase). OS-01 doesn't leave my hair crispy or greasy like Harklinikken's growth serum. The dermaroller does leave my scalp a little itchy, but I suspect that I'm just not used to it. I took before photos and look forward to seeing what happens.

    OneSkin
    2 weeks ago

    Hi Lauren!

    Thank you for the review! We are happy to hear you are enjoying OS-01 HAIR!

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01Β Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more atΒ oneskin.co/claims
02Β Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04Β https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05Β https://academic.oup.com/bbb/article/72/12/3211/5941013 06Β https://pubmed.ncbi.nlm.nih.gov/32522955/ 07Β https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886