To receive your order by December 25th, select UPS 2 or 3-day shipping at checkout
Last day to select UPS 3-day shipping is Wednesday, December 18th, to receive by December 25th
Last day to Select UPS 2-day shipping is Tuesday, December 19th, to receive by December 25th
Get a free travel size OS-01 BODY (a $37 value!) with orders over $125 | Ends 12/23
To receive your order by December 25th, select UPS 2 or 3-day shipping at checkout
Last day to select UPS 3-day shipping is Wednesday, December 18th, to receive by December 25th
Last day to Select UPS 2-day shipping is Tuesday, December 19th, to receive by December 25th
Get a free travel size OS-01 BODY (a $37 value!) with orders over $125 | Ends 12/23
improved skin eveness, radiance, pores + firmness°1 •Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication) ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz 87%6 reduction of fine lines + wrinkles° 100% skin smoothness + overall appearance
Powered by OS-01 The first peptide proven to reverse skin's biological age by preventing the accumulation of senescent cells. •1 • Shown in lab studies on human skin cells and/or samples (Zonari, et al., npj Aging, 2023)
OS-01 FACE induced a significant increase in epidermal thickness of 23%01 01Shown in lab studies on human skin samples (Zonari, et al., npj Aging, 2023)
BRAND PARTNE Skin SAFE TRUSTED CHOICE Designed to benefit all skin types ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz
Your Skin Longevity Routine ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Merceand yening HOW TO APPLY Apposin asadally essential moisturizer WHERE TO APPLY Face, neck and hands
КЕЕР Reusable Shell ONE SKIN 05-01 FACE DISCARD (AFTER USE) Refill Pouch/ Pump
ONE SKIN I've been using OS-01 for about a year as part of my health strategy to support aging in the best way possible. I'm in my early sixties and I get asked all the time why I have no fine lines or wrinkles. OS-01 is definitely part of the reason. Wish I'd found it in my 20s! Rachelle D. ‡7 • Customer | OS-01 FACE
  • improved skin eveness, radiance, pores + firmness°1 •Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication) ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz 87%6 reduction of fine lines + wrinkles° 100% skin smoothness + overall appearance
  • Powered by OS-01 The first peptide proven to reverse skin's biological age by preventing the accumulation of senescent cells. •1 • Shown in lab studies on human skin cells and/or samples (Zonari, et al., npj Aging, 2023)
  • OS-01 FACE induced a significant increase in epidermal thickness of 23%01 01Shown in lab studies on human skin samples (Zonari, et al., npj Aging, 2023)
  • BRAND PARTNE Skin SAFE TRUSTED CHOICE Designed to benefit all skin types ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz
  • Your Skin Longevity Routine ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Merceand yening HOW TO APPLY Apposin asadally essential moisturizer WHERE TO APPLY Face, neck and hands
  • КЕЕР Reusable Shell ONE SKIN 05-01 FACE DISCARD (AFTER USE) Refill Pouch/ Pump
  • ONE SKIN I've been using OS-01 for about a year as part of my health strategy to support aging in the best way possible. I'm in my early sixties and I get asked all the time why I have no fine lines or wrinkles. OS-01 is definitely part of the reason. Wish I'd found it in my 20s! Rachelle D. ‡7 • Customer | OS-01 FACE

Starter Kit

Refill

OS-01 FACE Topical Supplement

OS-01 AGE REVERSALTM TECHNOLOGY

$99 - Subscription / $120 - One Time Purchase

5160 reviews

50mL

Essential Moisturizer

OS-01 FACE is the first skin longevity treatment scientifically proven to target the root caus...

Select your plan

One-Time Purchase
Subscribe & Save
(Change, skip, or cancel anytime)
Deliver every
Try it risk-free! 45 day money back guarantee
improved skin eveness, radiance, pores + firmness°1 •Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication) ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz 87%6 reduction of fine lines + wrinkles° 100% skin smoothness + overall appearance
Powered by OS-01 The first peptide proven to reverse skin's biological age by preventing the accumulation of senescent cells. •1 • Shown in lab studies on human skin cells and/or samples (Zonari, et al., npj Aging, 2023)
OS-01 FACE induced a significant increase in epidermal thickness of 23%01 01Shown in lab studies on human skin samples (Zonari, et al., npj Aging, 2023)
BRAND PARTNE Skin SAFE TRUSTED CHOICE Designed to benefit all skin types ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz
Your Skin Longevity Routine ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Merceand yening HOW TO APPLY Apposin asadally essential moisturizer WHERE TO APPLY Face, neck and hands
КЕЕР Reusable Shell ONE SKIN 05-01 FACE DISCARD (AFTER USE) Refill Pouch/ Pump
ONE SKIN I've been using OS-01 for about a year as part of my health strategy to support aging in the best way possible. I'm in my early sixties and I get asked all the time why I have no fine lines or wrinkles. OS-01 is definitely part of the reason. Wish I'd found it in my 20s! Rachelle D. ‡7 • Customer | OS-01 FACE
  • improved skin eveness, radiance, pores + firmness°1 •Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication) ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz 87%6 reduction of fine lines + wrinkles° 100% skin smoothness + overall appearance
  • Powered by OS-01 The first peptide proven to reverse skin's biological age by preventing the accumulation of senescent cells. •1 • Shown in lab studies on human skin cells and/or samples (Zonari, et al., npj Aging, 2023)
  • OS-01 FACE induced a significant increase in epidermal thickness of 23%01 01Shown in lab studies on human skin samples (Zonari, et al., npj Aging, 2023)
  • BRAND PARTNE Skin SAFE TRUSTED CHOICE Designed to benefit all skin types ONE SKIN OS- 01 FACE TOPICAL SUPPLEMENT Essential Moisturizer 50 mL / 1.7 fl oz
  • Your Skin Longevity Routine ONE SKIN PREP PREP EYE FACE SHIELD WHEN TO APPLY Merceand yening HOW TO APPLY Apposin asadally essential moisturizer WHERE TO APPLY Face, neck and hands
  • КЕЕР Reusable Shell ONE SKIN 05-01 FACE DISCARD (AFTER USE) Refill Pouch/ Pump
  • ONE SKIN I've been using OS-01 for about a year as part of my health strategy to support aging in the best way possible. I'm in my early sixties and I get asked all the time why I have no fine lines or wrinkles. OS-01 is definitely part of the reason. Wish I'd found it in my 20s! Rachelle D. ‡7 • Customer | OS-01 FACE

Starter Kit

Refill

OS-01 FACE Topical Supplement

OS-01 AGE REVERSALTM TECHNOLOGY

$99 - Subscription / $120 - One Time Purchase

5160 reviews

50mL

Essential Moisturizer

OS-01 FACE is the first skin longevity treatment scientifically proven to target the root caus...

Select your plan

One-Time Purchase
Subscribe & Save
(Change, skip, or cancel anytime)
Deliver every
Try it risk-free! 45 day money back guarantee

THE BREAKTHROUGH SCIENCE

POWERED BY THE OS-01 SENESCENCE BLOCKING PEPTIDE TM

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03
Switches off senescent cells associated with aging to help skin behave like its younger self 01,02
Boosts biomarkers of healthy skin, including collagen and hyaluronic acid biosynthesis01,02
Supports activation of cellular repair pathways 01,02
Discover the science

THE BREAKTHROUGH SCIENCE

POWERED BY THE OS-01 SENESCENCE BLOCKING PEPTIDE TM

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03
Switches off senescent cells associated with aging to help skin behave like its younger self 01,02
Boosts biomarkers of healthy skin, including collagen and hyaluronic acid biosynthesis 01,02
Supports activation of cellular repair pathways 01,02
Discover the science

The Details

HOW TO INTEGRATE INTO YOUR ROUTINE

STEP 1: PREPSTEP 2: (optional) tonerSTEP 3: OS-01 EYE

STEP 4: OS-01 FACEApplying OS-01 FACE before additional steps in your skincare routine allows you to get the most benefit from the OS-01 peptide.

STEP 5: (optional) other treatments including serums, retinoids, hyaluronic acid, and red light therapySTEP 6: OS-01 SHIELDSTEP 7: (optional) make-up

HOW TO APPLY

  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

Pro tip: Double the penetration of the OS-01 peptide by cleansing with PREP first 01

The Details

HOW TO INTEGRATE INTO YOUR ROUTINE

STEP 1: PREPSTEP 2: (optional) tonerSTEP 3: OS-01 EYE

STEP 4: OS-01 FACEApplying OS-01 FACE before additional steps in your skincare routine allows you to get the most benefit from the OS-01 peptide.

STEP 5: (optional) other treatments including serums, retinoids, hyaluronic acid, and red light therapySTEP 6: OS-01 SHIELDSTEP 7: (optional) make-up

HOW TO APPLY

  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

Pro tip: Double the penetration of the OS-01 peptide by cleansing with PREP first 01

Results that go beyond the lab

After 12 Weeks

  • 95.5% of participants saw improved skin evenness, radiance, pores and firmness*
  • 87% of participants saw a reduction in the appearance of fine lines & wrinkles*
  • 100% of participants saw improved skin smoothness and overall appearance*
  • Participants skin’s barrier function improved by an average of + 15%*
*Shown in a 12-week clinical study performed by a third party research organization with 22 participants (OneSkin manuscript in process of publication)

Results that go beyond the lab

After 12 weeks

  • 95.5% of participants saw improved skin evenness, radiance, pores and firmness*
  • 87% of participants saw a reduction in the appearance of fine lines & wrinkles*
  • 100% of participants saw improved skin smoothness and overall appearance*
  • Participants skin’s barrier function improved by an average of + 15%*
*Shown in a 12-week clinical study performed by a third party research organization with 22 participants (Zonari, et al., Journal of Cosmetic Dermatology, 2024)01,04

Love this product! I've been using for a little over a month and I've noticed a smoother skin texture and overall skin tone. Was using products containing retinol before, which can dry out your face (especially in the winter). After switching to OneSkin and cutting out retinol, my redness and fine lines are finally going away. Excited to see even more improvement with more use!

Clay D.

Verified Buyer

Definitely impressed. Noticeable improvements in texture and evenness in about 30 days. The only other topical product that produced noticeable results for was a retinol cream, but the results of this product were more significant.
Dan

Verified Buyer

I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth...and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.

Tova N.

Verified Buyer

Great stuff! After spending 6+ months frustrated with my retinol regiment, I gave OneSkin a try. Less than 2 moths in, my skin is already more plump and elastic. I'm excited to see what results are still in store!

Colin B.

Verified Buyer

I've used retinol for years and stopped when I started this product. I'm on my third month and my skin looks better than it did 10 years ago. I'm 58 and was recently told that my face continues to look younger. I'm looking forward to more supplements coming out from OneSkin.

Lisa C.

Verified Buyer

Buy now

Love this product! I've been using for a little over a month and I've noticed a smoother skin texture and overall skin tone. Was using products containing retinol before, which can dry out your face (especially in the winter). After switching to OneSkin and cutting out retinol, my redness and fine lines are finally going away. Excited to see even more improvement with more use!

Clay D.

Verified Buyer

Definitely impressed. Noticeable improvements in texture and evenness in about 30 days. The only other topical product that produced noticeable results for was a retinol cream, but the results of this product were more significant.
Dan

Verified Buyer

I stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smooth...and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.

Tova N.

Verified Buyer

Great stuff! After spending 6+ months frustrated with my retinol regiment, I gave OneSkin a try. Less than 2 moths in, my skin is already more plump and elastic. I'm excited to see what results are still in store!

Colin B.

Verified Buyer

I've used retinol for years and stopped when I started this product. I'm on my third month and my skin looks better than it did 10 years ago. I'm 58 and was recently told that my face continues to look younger. I'm looking forward to more supplements coming out from OneSkin.

Lisa C.

Verified Buyer

Buy now