Gut Health and Skin: How Are They Connected?
6 min read
MAR 10, 2023
March 10,2023
HEALTH
Gut Health and Skin: How Are They Connected?
6 min read
MAR 10, 2023
March 10,2023
HEALTH
For decades, scientists have known that skin health starts from within. But where, exactly? Recent breakthroughs in the study of the human microbiome suggest that the key to skin health may actually start deep within our digestive system with the millions of microorganisms living in our gut. When our gut microbiome is in balance, our skin thrives. But when that microbial balance is off, our skin can suffer from conditions like psoriasis, acne, dandruff, and atopic dermatitis. [1,2]
For decades, scientists have known that skin health starts from within. But where, exactly? Recent breakthroughs in the study of the human microbiome suggest that the key to skin health may actually start deep within our digestive system with the millions of microorganisms living in our gut. When our gut microbiome is in balance, our skin thrives. But when that microbial balance is off, our skin can suffer from conditions like psoriasis, acne, dandruff, and atopic dermatitis. [1,2]
So, what does this mean for you and your skin? It means that along with using high-quality topical skin care products, supporting a healthy gut is crucial to skin health. Let’s take a closer look at the emerging science and what you can do to support gut health with your everyday habits.
So, what does this mean for you and your skin? It means that along with using high-quality topical skin care products, supporting a healthy gut is crucial to skin health. Let’s take a closer look at the emerging science and what you can do to support gut health with your everyday habits.
01
What is the Microbiome?
Our digestive tract is home to trillions of microorganisms: some beneficial and some harmful. When our gut microbiome is at its best, beneficial microorganisms outnumber pathogenic ones. But many aspects of modern living–including antibiotics, antibacterial products, and heavily processed foods–can throw off our microbial balance, giving pathogenic bacteria an advantage that can lead to unwanted health consequences. To understand why this matters, let’s take a closer look at three of the microbiome’s basic health functions.
01
What is the Microbiome?
Our digestive tract is home to trillions of microorganisms: some beneficial and some harmful. When our gut microbiome is at its best, beneficial microorganisms outnumber pathogenic ones. But many aspects of modern living–including antibiotics, antibacterial products, and heavily processed foods–can throw off our microbial balance, giving pathogenic bacteria an advantage that can lead to unwanted health consequences. To understand why this matters, let’s take a closer look at three of the microbiome’s basic health functions.
02
Nutrient Absorption and Metabolism
The food we eat gives us the nutrients we need for growth, energy, and cellular function. But absorbing the nutrients in our food doesn't happen automatically: the microbiota in our gut do much of this for us, transforming dietary nutrients into bioavailable forms that our bodies can absorb effectively. [4] In fact, many life-critical nutrients like vitamin K and vitamin B–essential for wound healing, cardiovascular function, and muscle development–are mainly processed by microorganisms in the gut. [4]This nutrient metabolism is symbiotic, meaning it benefits both us and the microbes living within us. For example, beneficial microorganisms from the lactobacillus and roseburia genera need plenty of vitamin A and vitamin C to grow. When we eat foods high in these vitamins, lactobacillus and roseburia thrive; in return, they break down hard-to-digest lactose, reduce cholesterol, and produce short-chain fatty acids (SCFAs) that are critical to our brain function.
02
Nutrient Absorption and Metabolism
The food we eat gives us the nutrients we need for growth, energy, and cellular function. But absorbing the nutrients in our food doesn't happen automatically: the microbiota in our gut do much of this for us, transforming dietary nutrients into bioavailable forms that our bodies can absorb effectively. [4] In fact, many life-critical nutrients like vitamin K and vitamin B–essential for wound healing, cardiovascular function, and muscle development–are mainly processed by microorganisms in the gut. [4]This nutrient metabolism is symbiotic, meaning it benefits both us and the microbes living within us. For example, beneficial microorganisms from the lactobacillus and roseburia genera need plenty of vitamin A and vitamin C to grow. When we eat foods high in these vitamins, lactobacillus and roseburia thrive; in return, they break down hard-to-digest lactose, reduce cholesterol, and produce short-chain fatty acids (SCFAs) that are critical to our brain function.
03
Immune Response
A recent review of six articles from the scientific journal Immunology concluded that our immune systems are developed in large part by the microbial communities we’re exposed to at birth. While the exact connection is still unclear, scientists believe there’s a link between the microbiome and immune-modulated conditions like autoimmune diseases, asthma, and allergies later in life. [5,6] Scientists continue to research these connections for potential immune system treatments. For example, emerging research suggests that colonizing a person’s digestive tract with beneficial microorganisms via fecal transplant could serve as an effective therapy for immune disorders. [5,6]
03
Immune Response
A recent review of six articles from the scientific journal Immunology concluded that our immune systems are developed in large part by the microbial communities we’re exposed to at birth. While the exact connection is still unclear, scientists believe there’s a link between the microbiome and immune-modulated conditions like autoimmune diseases, asthma, and allergies later in life. [5,6] Scientists continue to research these connections for potential immune system treatments. For example, emerging research suggests that colonizing a person’s digestive tract with beneficial microorganisms via fecal transplant could serve as an effective therapy for immune disorders. [5,6]
04
Inflammation
Perhaps the most exciting area of microbiome research explores its relationship to systemic inflammation. A growing body of research has shown that systemic inflammation is a common factor behind a broad range of chronic diseases, including cardiovascular disease, kidney disfunction, autoimmune disorders, and neurodegenerative disease. [7]So what does this have to do with your gut? Chronic inflammation may, in many cases, stem from an overabundance of specific gut bacteria. When these harmful bacteria grow out of control, they activate inflammatory pathways in the body, leading to system-wide inflammation. Microbial imbalance can also cause inflammation by affecting the permeability of the intestinal walls, creating what’s known as a “leaky gut.” When our microbiome is healthy, good bacteria keep our intestinal walls strong, protecting the rest of the body from our digestive waste. When our bacterial balance is off, our intestinal walls become weaker, allowing metabolites from our digestive tract to leak into the bloodstream, triggering an inflammatory response in the body. [7]
04
Inflammation
Perhaps the most exciting area of microbiome research explores its relationship to systemic inflammation. A growing body of research has shown that systemic inflammation is a common factor behind a broad range of chronic diseases, including cardiovascular disease, kidney disfunction, autoimmune disorders, and neurodegenerative disease. [7]So what does this have to do with your gut? Chronic inflammation may, in many cases, stem from an overabundance of specific gut bacteria. When these harmful bacteria grow out of control, they activate inflammatory pathways in the body, leading to system-wide inflammation. Microbial imbalance can also cause inflammation by affecting the permeability of the intestinal walls, creating what’s known as a “leaky gut.” When our microbiome is healthy, good bacteria keep our intestinal walls strong, protecting the rest of the body from our digestive waste. When our bacterial balance is off, our intestinal walls become weaker, allowing metabolites from our digestive tract to leak into the bloodstream, triggering an inflammatory response in the body. [7]
05
How are the Gut and Skin Connected?
Scientists refer to the interaction between the gut and skin as the “gut-skin axis”. Because the skin, in particular, is sensitive to systemic inflammation, it is exceedingly responsive to changes in the gut microbiome. This is why individuals who struggle with inflammatory digestive issues often see accompanying skin side effects. One symptom of inflammatory bowel disease (IBD), for example, are skin rashes or lesions. Research suggests that the connection also goes the other way: inflammatory skin diseases like psoriasis, acne, eczema, atopic dermatitis and rosacea may stem from microbiome imbalances. In fact, studies of people with rosacea show that certain bacteria are more abundant in their gut microbiomes than in the general population. [8,10]In addition to its inflammation-regulating functions, the gut microbiome is also a hormone-regulating center. In fact, intestinal microbes release at least 30 hormone-like compounds. [5,8] These compounds can have a direct impact on the skin–leading scientists to look further into the connection between the microbiome and hormone-modulated skin issues like acne.
05
How are the Gut and Skin Connected?
Scientists refer to the interaction between the gut and skin as the “gut-skin axis”. Because the skin, in particular, is sensitive to systemic inflammation, it is exceedingly responsive to changes in the gut microbiome. This is why individuals who struggle with inflammatory digestive issues often see accompanying skin side effects. One symptom of inflammatory bowel disease (IBD), for example, are skin rashes or lesions. Research suggests that the connection also goes the other way: inflammatory skin diseases like psoriasis, acne, eczema, atopic dermatitis and rosacea may stem from microbiome imbalances. In fact, studies of people with rosacea show that certain bacteria are more abundant in their gut microbiomes than in the general population. [8,10]In addition to its inflammation-regulating functions, the gut microbiome is also a hormone-regulating center. In fact, intestinal microbes release at least 30 hormone-like compounds. [5,8] These compounds can have a direct impact on the skin–leading scientists to look further into the connection between the microbiome and hormone-modulated skin issues like acne.
06
Is Gut Health Related to Acne?
Despite the fact that acne is one of the most studied skin diseases, the scientific jury is still out when it comes to the exact link between gut health and breakouts. Research shows that there are three primary factors behind the development of breakouts: ductal obstruction, sebum oversecretion, and inflammation caused by a bacteria called propionibacterium acnes. [9] While a proven link has yet to be confirmed, acne researchers hypothesize that certain intestinal flora may increase the production of hormones that trigger sebum secretion and skin inflammation. More sebum and higher inflammation creates the ideal environment for acne-causing bacteria to proliferate, leading to breakouts. Additionally, an unhealthy gut can make it difficult for your body to absorb nutrients like chromium, folic acid, selenium, and zinc – all of which are essential in keeping the skin healthy and acne-free. [9]
06
Is Gut Health Related to Acne?
Despite the fact that acne is one of the most studied skin diseases, the scientific jury is still out when it comes to the exact link between gut health and breakouts. Research shows that there are three primary factors behind the development of breakouts: ductal obstruction, sebum oversecretion, and inflammation caused by a bacteria called propionibacterium acnes. [9] While a proven link has yet to be confirmed, acne researchers hypothesize that certain intestinal flora may increase the production of hormones that trigger sebum secretion and skin inflammation. More sebum and higher inflammation creates the ideal environment for acne-causing bacteria to proliferate, leading to breakouts. Additionally, an unhealthy gut can make it difficult for your body to absorb nutrients like chromium, folic acid, selenium, and zinc – all of which are essential in keeping the skin healthy and acne-free. [9]
07
Is Gut Health Related to Aging?
Studies show that our microbial communities change as we age. In fact, it’s actually possible to estimate a person’s age within 4 years of accuracy just by analyzing their gut and skin microbes. While the research is still emerging, these age-related microbiome shifts may be the key to understanding how strengthening the gut-skin axis can be used to reverse the aging process. [12,13]Let’s take a closer look at what we know today about the connection. INFLAMMATION When the gut is out of whack, the body initiates a systemic immune response that results in a constant state of inflammation throughout the body. Over time, this can lead to an accelerated state of aging throughout the body. Even low levels of chronic inflammation fast-track the aging process and are closely linked to a number of age-related diseases. [6,11,12]SKIN AGINGAge-related microbiome changes may affect the skin’s production of moisturizing factors, creating an accelerated rate of skin aging. Information gathered from the National Center for Biotechnology found that bacterial pathways in the gut affect the body’s production of ceramides and fatty acids – natural moisturizers that fortify the skin barrier, maintain elasticity, and prevent sagging. [11,12,1]
07
Is Gut Health Related to Aging?
Studies show that our microbial communities change as we age. In fact, it’s actually possible to estimate a person’s age within 4 years of accuracy just by analyzing their gut and skin microbes. While the research is still emerging, these age-related microbiome shifts may be the key to understanding how strengthening the gut-skin axis can be used to reverse the aging process. [12,13]Let’s take a closer look at what we know today about the connection. INFLAMMATION When the gut is out of whack, the body initiates a systemic immune response that results in a constant state of inflammation throughout the body. Over time, this can lead to an accelerated state of aging throughout the body. Even low levels of chronic inflammation fast-track the aging process and are closely linked to a number of age-related diseases. [6,11,12]SKIN AGINGAge-related microbiome changes may affect the skin’s production of moisturizing factors, creating an accelerated rate of skin aging. Information gathered from the National Center for Biotechnology found that bacterial pathways in the gut affect the body’s production of ceramides and fatty acids – natural moisturizers that fortify the skin barrier, maintain elasticity, and prevent sagging. [11,12,1]
08
How Does My Gut Get Out of Balance?
We are what we eat — at least when it comes to our intestinal microbiota. The foods we consume either promote or inhibit the proliferation of microorganisms within our gut. A diet high in processed foods and added sugars may decrease the number of healthy bacteria in the gut and lead to inflammation. The following are other factors that affect gut health. [14]
- Not enough fiber. Fiber is prebiotic, meaning it promotes the growth of good gut bacteria.
- Too much alcohol. Alcohol can kill good gut bacteria and feed harmful bacteria with its high sugar content.
- Taking antibiotics. While antibiotics can be vital in certain situations, they also kill off huge numbers of gut bacteria, including the beneficial ones, & compromise your microbial balance.
- Tobacco use. Smoking fills your body with cancer-causing substances and is a risk factor behind several digestive diseases.
- Lack of sleep. Not getting enough sleep stresses your entire body and can decrease good bacteria in your gut.
- High stress. High levels of stress can decrease blood flow to the gut while increasing digestive sensitivity.
- Not enough exercise. Physical activity helps regulate your blood glucose levels. When these are off, your gut health may suffer.
08
How Does My Gut Get Out of Balance?
We are what we eat — at least when it comes to our intestinal microbiota. The foods we consume either promote or inhibit the proliferation of microorganisms within our gut. A diet high in processed foods and added sugars may decrease the number of healthy bacteria in the gut and lead to inflammation. The following are other factors that affect gut health. [14]
- Not enough fiber. Fiber is prebiotic, meaning it promotes the growth of good gut bacteria.
- Too much alcohol. Alcohol can kill good gut bacteria and feed harmful bacteria with its high sugar content.
- Taking antibiotics. While antibiotics can be vital in certain situations, they also kill off huge numbers of gut bacteria, including the beneficial ones, & compromise your microbial balance.
- Tobacco use. Smoking fills your body with cancer-causing substances and is a risk factor behind several digestive diseases.
- Lack of sleep. Not getting enough sleep stresses your entire body and can decrease good bacteria in your gut.
- High stress. High levels of stress can decrease blood flow to the gut while increasing digestive sensitivity.
- Not enough exercise. Physical activity helps regulate your blood glucose levels. When these are off, your gut health may suffer.
10
How to Maintain a Healthy Gut Microbiome
Maintaining a healthy gut means creating an environment favorable to good microbes and unfavorable to the bad microorganisms within the digestive tract. Here are a few easy ways to foster a positive gut environment:
- Sleep Plenty: To help your body repair itself and keep stress levels low.
- Manage Stress: To reduce inflammation throughout the body.
- Stay Hydrated: To protect the mucosal gut lining and keep bowel movements regular.
- Eat Slowly: To thoroughly break down your food & support healthy digestion
- Eat for Microbiome Balance: A high-fiber, low-sugar diet with minimally processed foods has been shown to support gut health 8,14 Try to also eat plenty of:
- Fermented foods such as kimchi, yogurt, sauerkraut and miso.
- Longevity-promoting foods like bone broth, salmon, and lean meats.
- High-fiber foods like bananas, peas, legumes, and oats.
- Prebiotic & probiotic supplements: Probiotics seed your gut with good bacteria, while prebiotics feed the beneficial bacteria that aid in maintaining a healthy digestive system.
10
How to Maintain a Healthy Gut Microbiome
Maintaining a healthy gut means creating an environment favorable to good microbes and unfavorable to the bad microorganisms within the digestive tract. Here are a few easy ways to foster a positive gut environment:
- Sleep Plenty: To help your body repair itself and keep stress levels low.
- Manage Stress: To reduce inflammation throughout the body.
- Stay Hydrated: To protect the mucosal gut lining and keep bowel movements regular.
- Eat Slowly: To thoroughly break down your food & support healthy digestion
- Eat for Microbiome Balance: A high-fiber, low-sugar diet with minimally processed foods has been shown to support gut health 8,14 Try to also eat plenty of:
- Fermented foods such as kimchi, yogurt, sauerkraut and miso.
- Longevity-promoting foods like bone broth, salmon, and lean meats.
- High-fiber foods like bananas, peas, legumes, and oats.
- Prebiotic & probiotic supplements: Probiotics seed your gut with good bacteria, while prebiotics feed the beneficial bacteria that aid in maintaining a healthy digestive system.
11
How Do I know if My Gut Health is Off?
Because every person’s microbial community is unique to them, there’s no single definition of a normal microbiome. However, there are certain telltale signs that your microbial balance is off. You can tell your gut microbiome is out of balance if you experience the following symptoms: [3,4]
- Stomach disturbances like excess gas, constipation, diarrhea, or bloating.
- Sudden and unintentional weight changes.
- Skin changes or irritation.
- Excessive or constant fatigue
- Sleep disturbances like insomnia
- Food intolerances
11
How Do I know if My Gut Health is Off?
Because every person’s microbial community is unique to them, there’s no single definition of a normal microbiome. However, there are certain telltale signs that your microbial balance is off. You can tell your gut microbiome is out of balance if you experience the following symptoms: [3,4]
- Stomach disturbances like excess gas, constipation, diarrhea, or bloating.
- Sudden and unintentional weight changes.
- Skin changes or irritation.
- Excessive or constant fatigue
- Sleep disturbances like insomnia
- Food intolerances
12
Can I Tell My Gut-Skim Axis is Unhealthy by Looking at My Skin?
Not all skin issues start in the gut; however, if your skin suddenly appears inflamed and feels itchy, you may want to track your diet and digestion patterns for a link and look into eating more of the best foods for skin repair.You may also want to look into a probiotic supplement. One study showed that people who consumed lactobacillus paracasei supplements for 2 months had decreased skin sensitivity and enhanced skin barrier integrity. [15]
12
Can I Tell My Gut-Skim Axis is Unhealthy by Looking at My Skin?
Not all skin issues start in the gut; however, if your skin suddenly appears inflamed and feels itchy, you may want to track your diet and digestion patterns for a link and look into eating more of the best foods for skin repair.You may also want to look into a probiotic supplement. One study showed that people who consumed lactobacillus paracasei supplements for 2 months had decreased skin sensitivity and enhanced skin barrier integrity. [15]
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Key Takeaways:
- Scientists believe gut health and skin health are highly connected.
- Poor gut health can create inflammation throughout the entire body, especially in the skin.
- Early research suggests poor gut health may be a factor behind acne and skin aging.
- You can improve your gut health through diet and lifestyle changes.
- Because an unbalanced gut microbiome may accelerate aging, take steps to maintain a healthy digestive microbiota.
Key Takeaways:
- Scientists believe gut health and skin health are highly connected.
- Poor gut health can create inflammation throughout the entire body, especially in the skin.
- Early research suggests poor gut health may be a factor behind acne and skin aging.
- You can improve your gut health through diet and lifestyle changes.
- Because an unbalanced gut microbiome may accelerate aging, take steps to maintain a healthy digestive microbiota.
References
- De Pessemier, Britta et al. “Gut-Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions.” Microorganisms vol. 9,2 353. 11 Feb. 2021, doi:10.3390/microorganisms9020353
- "The Microbiome." HSPH Harvard. https://www.hsph.harvard.edu/nutritionsource/microbiome/
- "What is Homeostasis?" Scientific American. 3 January, 2000. https://www.scientificamerican.com/article/what-is-homeostasis/
- Frame, Leigh A et al. “Current explorations of nutrition and the gut microbiome: a comprehensive evaluation of the review literature.” Nutrition reviews vol. 78,10 (2020): 798-812. doi:10.1093/nutrit/nuz106
- La Flamme, Anne Camille, and Simon Milling. “Immunological partners: the gut microbiome in homeostasis and disease.” Immunology vol. 161,1 (2020): 1-3. doi:10.1111/imm.13247
- "Babies' gut bacteria affected by delivery method." Science Daily. https://www.sciencedaily.com/releases/2019/09/190918131447.htm
- Al Bander, Zahraa et al. “The Gut Microbiota and Inflammation: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618
- Salem, Iman et al. “The Gut Microbiome as a Major Regulator of the Gut-Skin Axis.” Frontiers in microbiology vol. 9 1459. 10 Jul. 2018, doi:10.3389/fmicb.2018.01459
- Lee, Young Bok et al. “Potential Role of the Microbiome in Acne: A Comprehensive Review.” Journal of clinical medicine vol. 8,7 987. 7 Jul. 2019, doi:10.3390/jcm8070987
- Fields, Deborah. "Gastrointestinal Disease and Skin Problems." News Medical. https://www.news-medical.net/health/Gastrointestinal-Disease-and-Skin-Problems.aspx
- Stocum, Linda. "Gut Bacteria Linked to Inflammatory Skin Disease." Dermatology Times. 11 May, 2021. https://www.dermatologytimes.com/view/gut-bacteria-linked-to-inflammatory-skin-disease
- Uildriks, Lori. "Harnessing the skin’s microbiome could help combat skin aging." Medical News Today.11 November, 2021. https://www.medicalnewstoday.com/articles/harnessing-the-skins-microbiome-could-help-combat-skin-aging
- Huang, Shi et al. “Human Skin, Oral, and Gut Microbiomes Predict Chronological Age.” mSystems vol. 5,1 e00630-19. 11 Feb. 2020, doi:10.1128/mSystems.00630-19
- Begum, Jabeen. "What Are the Symptoms of an Unhealthy Gut?" Medicine Net. 12 July, 2021. https://www.medicinenet.com/what_are_the_symptoms_of_an_unhealthy_gut/article.htm
- Traub, Michael. "Probiotic Treatment of Sensitive Skin." Natural Medicine Journal. https://www.naturalmedicinejournal.com/journal/2014-07/probiotic-treatment-sensitive-skin
References
- De Pessemier, Britta et al. “Gut-Skin Axis: Current Knowledge of the Interrelationship between Microbial Dysbiosis and Skin Conditions.” Microorganisms vol. 9,2 353. 11 Feb. 2021, doi:10.3390/microorganisms9020353
- "The Microbiome." HSPH Harvard. https://www.hsph.harvard.edu/nutritionsource/microbiome/
- "What is Homeostasis?" Scientific American. 3 January, 2000. https://www.scientificamerican.com/article/what-is-homeostasis/
- Frame, Leigh A et al. “Current explorations of nutrition and the gut microbiome: a comprehensive evaluation of the review literature.” Nutrition reviews vol. 78,10 (2020): 798-812. doi:10.1093/nutrit/nuz106
- La Flamme, Anne Camille, and Simon Milling. “Immunological partners: the gut microbiome in homeostasis and disease.” Immunology vol. 161,1 (2020): 1-3. doi:10.1111/imm.13247
- "Babies' gut bacteria affected by delivery method." Science Daily. https://www.sciencedaily.com/releases/2019/09/190918131447.htm
- Al Bander, Zahraa et al. “The Gut Microbiota and Inflammation: An Overview.” International journal of environmental research and public health vol. 17,20 7618. 19 Oct. 2020, doi:10.3390/ijerph17207618
- Salem, Iman et al. “The Gut Microbiome as a Major Regulator of the Gut-Skin Axis.” Frontiers in microbiology vol. 9 1459. 10 Jul. 2018, doi:10.3389/fmicb.2018.01459
- Lee, Young Bok et al. “Potential Role of the Microbiome in Acne: A Comprehensive Review.” Journal of clinical medicine vol. 8,7 987. 7 Jul. 2019, doi:10.3390/jcm8070987
- Fields, Deborah. "Gastrointestinal Disease and Skin Problems." News Medical. https://www.news-medical.net/health/Gastrointestinal-Disease-and-Skin-Problems.aspx
- Stocum, Linda. "Gut Bacteria Linked to Inflammatory Skin Disease." Dermatology Times. 11 May, 2021. https://www.dermatologytimes.com/view/gut-bacteria-linked-to-inflammatory-skin-disease
- Uildriks, Lori. "Harnessing the skin’s microbiome could help combat skin aging." Medical News Today.11 November, 2021. https://www.medicalnewstoday.com/articles/harnessing-the-skins-microbiome-could-help-combat-skin-aging
- Huang, Shi et al. “Human Skin, Oral, and Gut Microbiomes Predict Chronological Age.” mSystems vol. 5,1 e00630-19. 11 Feb. 2020, doi:10.1128/mSystems.00630-19
- Begum, Jabeen. "What Are the Symptoms of an Unhealthy Gut?" Medicine Net. 12 July, 2021. https://www.medicinenet.com/what_are_the_symptoms_of_an_unhealthy_gut/article.htm
- Traub, Michael. "Probiotic Treatment of Sensitive Skin." Natural Medicine Journal. https://www.naturalmedicinejournal.com/journal/2014-07/probiotic-treatment-sensitive-skin
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
Peptides: The First Piece Of The Skin Longevity Pu...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
Discover More
7 Benefits of Niacinamide For Your Skin
Seeing is Believing: Discover The Eyelifting Resul...
How To Turn Your Skin Care Resolutions Into Skin C...
What Does Clean Beauty Mean, And Why Does Safe Bea...
Winter Skincare - How To Prevent Dry Skin this Sea...
What Are Chemical Peels & Are There Alternatives?
How Relationships, Community, & Social Interaction...
Hair Loss 101: Combing Through the Science of Hair...
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
Peptides: The First Piece Of The Skin Longevity Pu...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging