How is OS-01 EYE different from OS-01 FACE?
4 min read
April 25,2023
ONESKIN PRODUCTS
How is OS-01 EYE different from OS-01 FACE?
4 min read
April 25,2023
ONESKIN PRODUCTS
Many of us have spent decades wondering if we really need any eye cream. How different can they actually be from the products we’re already using on the rest of the face? When we set out to formulate OS-01 EYE, it was important to us to create a product that was functionally different from OS-01 FACE – and specifically designed to treat the skin around the eyes. One thing both formulas have in common? OS-01, our breakthrough innovation and the first peptide proven to reduce skin’s biological age, support cellular repair, increase epidermal thickness, improve barrier function, and increase biomarkers associated with collagen production.[1, 2, 3] To understand how and why the two formulas are different, let’s take a closer look at the science.
Many of us have spent decades wondering if we really need any eye cream. How different can they actually be from the products we’re already using on the rest of the face? When we set out to formulate OS-01 EYE, it was important to us to create a product that was functionally different from OS-01 FACE – and specifically designed to treat the skin around the eyes. One thing both formulas have in common? OS-01, our breakthrough innovation and the first peptide proven to reduce skin’s biological age, support cellular repair, increase epidermal thickness, improve barrier function, and increase biomarkers associated with collagen production.[1, 2, 3] To understand how and why the two formulas are different, let’s take a closer look at the science.
01
How Is Eye-Area Skin Actually Different?
The skin around the eyes is very thin, with a stratum corneum that’s on average about 3 layers thick compared to 15+ layers on other areas.[4] This incredible skin thinness means your under eyes experience more exaggerated signs of collagen and elastin loss than the rest of your face–namely fine lines, sagging, and crepiness. [5,6]Eye-area skin has also been shown to actually age faster than the rest of our faces. In a study, scientists measured the biological age of eye skin and compared it to skin just inches away on the temple. What they found was that the skin under the eyes was biologically 22.25 years older. [6]This difference in biological age may be largely due to increased rates of cellular senescence around the eyes. In a study, scientists analyzed the expression of a key senescence marker, CDK2NA, in periocular skin. What they found was that periocular skin expressed significantly higher levels of cellular senescence than other areas of the face. [6]
01
How Is Eye-Area Skin Actually Different?
The skin around the eyes is very thin, with a stratum corneum that’s on average about 3 layers thick compared to 15+ layers on other areas.[4] This incredible skin thinness means your under eyes experience more exaggerated signs of collagen and elastin loss than the rest of your face–namely fine lines, sagging, and crepiness. [5,6]Eye-area skin has also been shown to actually age faster than the rest of our faces. In a study, scientists measured the biological age of eye skin and compared it to skin just inches away on the temple. What they found was that the skin under the eyes was biologically 22.25 years older. [6]This difference in biological age may be largely due to increased rates of cellular senescence around the eyes. In a study, scientists analyzed the expression of a key senescence marker, CDK2NA, in periocular skin. What they found was that periocular skin expressed significantly higher levels of cellular senescence than other areas of the face. [6]
02
How is OS-01 EYE Different from OS-01 FACE?
In order to address the significantly higher levels of cellular senescence around the eyes, we formulated OS-01 EYE with the highest concentration of our OS-01 peptide. In lab studies on human skin samples, the OS-01 peptide was shown to reduce the overall number of senescent cells.[1, 3] By powering OS-01 EYE with more OS-01 peptide, it is better equipped to help counteract the accelerated aging process that occurs around the eyes.In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients, carefully blended to be gentle on sensitive and problematic skin. As always, we chose scientifically validated ingredients that magnify the benefits of the OS-01 peptide, offering additional damage repair benefits, barrier support, and enhanced hydration.
02
How is OS-01 EYE Different from OS-01 FACE?
In order to address the significantly higher levels of cellular senescence around the eyes, we formulated OS-01 EYE with the highest concentration of our OS-01 peptide. In lab studies on human skin samples, the OS-01 peptide was shown to reduce the overall number of senescent cells.[1, 3] By powering OS-01 EYE with more OS-01 peptide, it is better equipped to help counteract the accelerated aging process that occurs around the eyes.In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients, carefully blended to be gentle on sensitive and problematic skin. As always, we chose scientifically validated ingredients that magnify the benefits of the OS-01 peptide, offering additional damage repair benefits, barrier support, and enhanced hydration.
03
What are the Supporting Ingredients in OS-01 EYE?
- Moringa Oleifera Seed Extract: Extracted from the seeds of the moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
- Vitamin E and Ubiquinone: Delivers high concentrations of antioxidants via coenzyme Q10 and vitamin E to shield against extrinsic aging factors.
- Fucus Vesiculosus Algae Extract: This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
- Biomimetic Vegan Collagen: This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.
- Cystoseira Humilis Seaweed Extract: This antioxidant-packed seaweed extract is rich in bioactive moisturizers that improve firmness, hydration and skin protection.
- Coffee Extract: Extracted from organic green coffee beans, this extract stimulates mitochondrial function to support skin cell regeneration.
- Acetyl Hexapeptide-8 (Argireline): This peptide reduces the look of wrinkles by limiting the overproduction of neurotransmitters that control facial muscle contractions.
03
What are the Supporting Ingredients in OS-01 EYE?
- Moringa Oleifera Seed Extract: Extracted from the seeds of the moringa tree, this extract protects skin cells against environmental pollutants that can trigger skin aging.
- Vitamin E and Ubiquinone: Delivers high concentrations of antioxidants via coenzyme Q10 and vitamin E to shield against extrinsic aging factors.
- Fucus Vesiculosus Algae Extract: This algae-derived extract helps reduce the appearance of dark circles and crow’s feet while enhancing overall skin luminosity.
- Biomimetic Vegan Collagen: This biodesigned vegan collagen peptide is the first human mimetic and boosts elastin, laminin, collagen and fibronectin while most topical collagen fails to penetrate the skin barrier.
- Cystoseira Humilis Seaweed Extract: This antioxidant-packed seaweed extract is rich in bioactive moisturizers that improve firmness, hydration and skin protection.
- Coffee Extract: Extracted from organic green coffee beans, this extract stimulates mitochondrial function to support skin cell regeneration.
- Acetyl Hexapeptide-8 (Argireline): This peptide reduces the look of wrinkles by limiting the overproduction of neurotransmitters that control facial muscle contractions.
04
What are the Supporting Ingredients in OS-01 FACE?
- Pracaxi Oil: Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
- Andiroba Oil: A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
- Niacinamide: A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
- Oleic Pau Mulato extract: An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
- Allantoin: A skin-conditioning molecule that moisturizes and soothes irritated skin.
- Hyaluronic acid: A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
04
What are the Supporting Ingredients in OS-01 FACE?
- Pracaxi Oil: Known for its moisturizing, anti-inflammatory, antioxidant, anti-bacterial, and anti-fungal properties.
- Andiroba Oil: A seed oil that promotes healthy collagen and minimizes the effects of inflammation.
- Niacinamide: A form of vitamin B that improves skin texture by promoting protein synthesis at the epidermal layer.
- Oleic Pau Mulato extract: An Amazonian tree extract that smooths wrinkles, minimizes skin stress and supports skin healing.
- Allantoin: A skin-conditioning molecule that moisturizes and soothes irritated skin.
- Hyaluronic acid: A hydrating acid included in three molecular weights so that it can boost collagen and elastin, support epidermal regeneration, and maintain moisture in every layer of the skin.
05
How Does OS-01 EYE Specifically Benefit Skin Around the Eyes?
In a 12-week clincial study, OS-01 EYE significantly improved hydration, elasticity, and firmness, as measured by instrumental analysis to remain completely unbiased. In addition, OS-01 EYE improved skin barrier function by an average of +17%, also measured by instrumental analysis. 96% of users noticed an improvement in tone, texture, and overall appearance, and 92% noticed an improvement in radiance.
05
How Does OS-01 EYE Specifically Benefit Skin Around the Eyes?
In a 12-week clincial study, OS-01 EYE significantly improved hydration, elasticity, and firmness, as measured by instrumental analysis to remain completely unbiased. In addition, OS-01 EYE improved skin barrier function by an average of +17%, also measured by instrumental analysis. 96% of users noticed an improvement in tone, texture, and overall appearance, and 92% noticed an improvement in radiance.
06
How Does OS-01 FACE Specifically Benefit Skin On The Face?
In a 12-week clinical study, OS-01 FACE was shown to have visible benefits on the face. At least 90% of users saw an improvement in skin elasticity, evenness, radiance, pores and firmness. 87% of users saw a reduction in fine lines and wrinkles while 100% of users saw an improvement in skin smoothness and overall appearance. Plus, OS-01 FACE has been shown to improve skin barrier function by an average of +15%, helping to enhance the skin's ability to protect against environmental aggressors.
06
How Does OS-01 FACE Specifically Benefit Skin On The Face?
In a 12-week clinical study, OS-01 FACE was shown to have visible benefits on the face. At least 90% of users saw an improvement in skin elasticity, evenness, radiance, pores and firmness. 87% of users saw a reduction in fine lines and wrinkles while 100% of users saw an improvement in skin smoothness and overall appearance. Plus, OS-01 FACE has been shown to improve skin barrier function by an average of +15%, helping to enhance the skin's ability to protect against environmental aggressors.
07
How Should You Use OS-01 EYE With OS-01 FACE?
To get maximum benefits from both formulas, apply OS-01 EYE 2x daily to the skin around the eyes just after cleansing with PREP. Follow with OS-01 FACE on the rest of your face.
07
How Should You Use OS-01 EYE With OS-01 FACE?
To get maximum benefits from both formulas, apply OS-01 EYE 2x daily to the skin around the eyes just after cleansing with PREP. Follow with OS-01 FACE on the rest of your face.
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Key Takeaways:
- OS-01 EYE was formulated specifically for the thinner skin around the eyes, which shows higher rates of cellular senescence and accelerated aging.
- To address this difference in eye skin, we infused OS-01 EYE with a higher concentration of our OS-01 peptide than what we use in OS-01 FACE.
- In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients selected for their areas of focus.
- To use OS-01 EYE and OS-01 FACE together, apply OS-01 EYE twice daily before applying OS-01 FACE.
Key Takeaways:
- OS-01 EYE was formulated specifically for the thinner skin around the eyes, which shows higher rates of cellular senescence and accelerated aging.
- To address this difference in eye skin, we infused OS-01 EYE with a higher concentration of our OS-01 peptide than what we use in OS-01 FACE.
- In addition to different concentrations of the OS-01 peptide, OS-01 EYE and OS-01 FACE contain different supporting ingredients selected for their areas of focus.
- To use OS-01 EYE and OS-01 FACE together, apply OS-01 EYE twice daily before applying OS-01 FACE.
References
- https://www.nature.com/articles/s41514-023-00109-1
- https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.16242
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- https://doi.org/10.1111/j.1468-2494.2008.00459.x
- https://pubmed.ncbi.nlm.nih.gov/17136094/
- https://www.jaad.org/article/S0190-9622(16)00242-5/abstract
References
- https://www.nature.com/articles/s41514-023-00109-1
- https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.16242
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- https://doi.org/10.1111/j.1468-2494.2008.00459.x
- https://pubmed.ncbi.nlm.nih.gov/17136094/
- https://www.jaad.org/article/S0190-9622(16)00242-5/abstract
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging