Our Story: Learn more about the history of OneSkin & the scientists behind our product.

3 min read

Feb 2nd, 2022

February 02,2022

FROM THE ONESKIN LAB

Our Story: Learn more about the history of OneSkin & the scientists behind our product.

3 min read

Feb 2nd, 2022

February 02,2022

FROM THE ONESKIN LAB

What happens when four longevity scientists discover that they can reverse the age of your skin? OneSkin: a breakthrough line of skin health products powered by longevity science to address the root causes of aging.

01

Born in the Lab

Our story began in a doctorate lab in Brazil, where our founding team met while completing their PhDs. Carolina, Alessandra, Mariana, and Juliana bonded over their shared interest in longevity science and their dreams of making age-related diseases a thing of the past.Together, the group explored their shared interest in skin–and its potential as the body’s largest organ to unlock the secrets to whole-system longevity. Our founders understood that if they could effectively slow the rate of skin aging, they could promote overall body health–complementing longevity practices and personalized medicine to optimize human living.

01

Born in the Lab

Our story began in a doctorate lab in Brazil, where our founding team met while completing their PhDs. Carolina, Alessandra, Mariana, and Juliana bonded over their shared interest in longevity science and their dreams of making age-related diseases a thing of the past.Together, the group explored their shared interest in skin–and its potential as the body’s largest organ to unlock the secrets to whole-system longevity. Our founders understood that if they could effectively slow the rate of skin aging, they could promote overall body health–complementing longevity practices and personalized medicine to optimize human living.

02

Our Origins as a Research Company

A few patents and papers later, our founders joined forces to start a research company dedicated to testing the anti-aging efficacy of topical skincare using their breakthrough invention, MolClock, the first ever skin-specific molecular clock. This advanced algorithm identifies the skin’s molecular age based on DNA methylation – an important indicator of overall skin health. By analyzing skin age with MolClock before and after the application of topical products, our team discovered how to quantify the efficacy of skin products at the molecular level.The team put thousands of ingredients and cosmetic formulations to the test. What they discovered was shocking: not only are most skincare products ineffective, many actually accelerate skin aging at the cellular level. While the team never set out to create skin products, they knew they had to get involved–formulating a new kind of skin care that actually lived up to their high scientific standards.Together, they embarked on a mission they never intended to pursue, but haven't stopped chasing since: revolutionizing the skin care industry by developing proven products that actually reverse aging at the molecular level.

02

Our Origins as a Research Company

A few patents and papers later, our founders joined forces to start a research company dedicated to testing the anti-aging efficacy of topical skincare using their breakthrough invention, MolClock, the first ever skin-specific molecular clock. This advanced algorithm identifies the skin’s molecular age based on DNA methylation – an important indicator of overall skin health. By analyzing skin age with MolClock before and after the application of topical products, our team discovered how to quantify the efficacy of skin products at the molecular level.The team put thousands of ingredients and cosmetic formulations to the test. What they discovered was shocking: not only are most skincare products ineffective, many actually accelerate skin aging at the cellular level. While the team never set out to create skin products, they knew they had to get involved–formulating a new kind of skin care that actually lived up to their high scientific standards.Together, they embarked on a mission they never intended to pursue, but haven't stopped chasing since: revolutionizing the skin care industry by developing proven products that actually reverse aging at the molecular level.

03

Discovering the OS-01 Peptide

To revolutionize the way people care for their skin, our team needed to discover a technology unlike anything on the market. So, they got to work doing what they do best: identifying new molecules and analyzing their effects on the skin at the cellular level. While many skincare companies make claims about aging, OneSkin is the first company that replicates skin aging in the lab to validate the efficacy of our products at the cellular level. After analyzing thousands of peptides, our founders discovered OS-01: the first peptide proven to reverse aging on the molecular level by reducing the accumulation of senescent cells in skin.* Learn more about cellular senescence here.*Shown in lab studies on huan skin samples and/or cells (Zonari, A., et al. npj Aging, 2023)

03

Discovering the OS-01 Peptide

To revolutionize the way people care for their skin, our team needed to discover a technology unlike anything on the market. So, they got to work doing what they do best: identifying new molecules and analyzing their effects on the skin at the cellular level. While many skincare companies make claims about aging, OneSkin is the first company that replicates skin aging in the lab to validate the efficacy of our products at the cellular level. After analyzing thousands of peptides, our founders discovered OS-01: the first peptide proven to reverse aging on the molecular level by reducing the accumulation of senescent cells in skin.* Learn more about cellular senescence here.*Shown in lab studies on huan skin samples and/or cells (Zonari, A., et al. npj Aging, 2023)

04

Looking to the Future

Thanks to our founders, science is in the OneSkin DNA. Most “science-backed” skincare companies are led by marketing teams that outsource their research to external labs. OneSkin is different. We’re led by scientists who run our end-to-end R&D process in-house and adhere to the strict rigor of the scientific process. The result? Research first. Products second. Data-validated claims always.Fueled by our passion for science and our love of life, we’re on a mission to revolutionize the way humans experience aging.

04

Looking to the Future

Thanks to our founders, science is in the OneSkin DNA. Most “science-backed” skincare companies are led by marketing teams that outsource their research to external labs. OneSkin is different. We’re led by scientists who run our end-to-end R&D process in-house and adhere to the strict rigor of the scientific process. The result? Research first. Products second. Data-validated claims always.Fueled by our passion for science and our love of life, we’re on a mission to revolutionize the way humans experience aging.

05

Meet The Team

05

Meet The Team

Carolina Reis Oliveira, PhD; Co-Founder and Chief Executive Officer (CEO)

Ph.D. in Immunology, Federal University of Minas Gerais in collaboration with Rutgers University
Alumnus of IndieBio, the world's leading biotechnology accelerator
Co-inventor of three patents

“By addressing aging, we can be more effective in preventing most of the individual diseases we struggle to treat. I dream of a future in which everyone will live free from limitations associated with aging. If I can help move the needle towards that future, I will have fulfilled my life’s purpose.”

Carolina Reis Oliveira, PhD; Co-Founder and Chief Executive Officer (CEO)

Ph.D. in Immunology, Federal University of Minas Gerais in collaboration with Rutgers University
Alumnus of IndieBio, the world's leading biotechnology accelerator
Co-inventor of three patents

“By addressing aging, we can be more effective in preventing most of the individual diseases we struggle to treat. I dream of a future in which everyone will live free from limitations associated with aging. If I can help move the needle towards that future, I will have fulfilled my life’s purpose.”

Alessandra Zonari, PhD; Co-Founder and Chief Scientific Officer (CSO)

PhD in skin regeneration and tissue engineering, Federal University of Minas Gerais in collaboration with 3B’s Research Group in Portugal
Second post-doctoral, University of Coimbra, Portugal
Co-inventor of three patents

Author of 20 peer-reviewed papers published in scientific journals“Over the past decade, I’ve focused my research on understanding skin biology and skin regeneration. For me, OneSkin became the connecting dot—it’s where I unite my research with my dream of extending the years that people can spend in good health.”

Alessandra Zonari, PhD; Co-Founder and Chief Scientific Officer (CSO)

PhD in skin regeneration and tissue engineering, Federal University of Minas Gerais in collaboration with 3B’s Research Group in Portugal
Second post-doctoral, University of Coimbra, Portugal
Co-inventor of three patents

Author of 20 peer-reviewed papers published in scientific journals“Over the past decade, I’ve focused my research on understanding skin biology and skin regeneration. For me, OneSkin became the connecting dot—it’s where I unite my research with my dream of extending the years that people can spend in good health.”

Mariana Boroni, PhD; Co-Founder

PhD in bioinformatics with an emphasis in genomics, Federal University of Minas Gerais with post-doctorate at the Gene Center at LMU, Germany.
Head of the Bioinformatics and Computational Biology Lab, Brazilian National Cancer Institute (INCA)
Co-inventor of four patents
Author of 26 peer-reviewed papers published in scientific journals

“I was diagnosed with cancer at 13, an experience that motivated me to research pathologies like cancer and age-related diseases and develop technologies that help people to lead healthier lives. My experiences have propelled my desire to use science to create a better future for the world.”

Mariana Boroni, PhD; Co-Founder

PhD in bioinformatics with an emphasis in genomics, Federal University of Minas Gerais with post-doctorate at the Gene Center at LMU, Germany.
Head of the Bioinformatics and Computational Biology Lab, Brazilian National Cancer Institute (INCA)
Co-inventor of four patents
Author of 26 peer-reviewed papers published in scientific journals

“I was diagnosed with cancer at 13, an experience that motivated me to research pathologies like cancer and age-related diseases and develop technologies that help people to lead healthier lives. My experiences have propelled my desire to use science to create a better future for the world.”

Juliana Carvalho, PhD; Co-Founder

PhD in molecular biology, Federal University of Minas Gerais
Professor of Pathology, Catholic University of Brasilia
Co-inventor of four patents
Author of 34 peer-reviewed papers published in scientific journals

“I feel tremendous privilege that I have the opportunity to generate new technologies and use my knowledge for the benefits of others. I love being a part of a new generation of scientists. The best way to achieve a brighter future is to build it.”

Juliana Carvalho, PhD; Co-Founder

PhD in molecular biology, Federal University of Minas Gerais
Professor of Pathology, Catholic University of Brasilia
Co-inventor of four patents
Author of 34 peer-reviewed papers published in scientific journals

“I feel tremendous privilege that I have the opportunity to generate new technologies and use my knowledge for the benefits of others. I love being a part of a new generation of scientists. The best way to achieve a brighter future is to build it.”

Discover More

Why Men Shouldn’t Ignore Skin Care: What’s Missing...

Navigating Skin Longevity: The Industry, The Scien...

What’s the Difference Between Dry and Dehydrated S...

How to Keep Your Hair Healthy and Strong During Pe...

What are Zombie Cells & How Can We Remove Them?

Collagen For Menopause: Why Is It Necessary For Healthy Skin Aging?

Collagen During Menopause: Is It Necessary For Hea...

Behind the Seal: How OneSkin Achieved the National...

Sun Sensitivity And Menopause: Protecting Your Cha...

Peptides Vs Growth Factors: Which is Better For Sk...

Hyperpigmentation and Menopause: Understanding and...

Skin Care is Health Care: Why Skin Care is the Key...

How Do Our Products Work Together?

The Connection Between Mental Health, Age Percepti...

OneSkin launches MolClock, the first skin-specific molecular clock to determine the biological age of human skin - One Skin Technologies

MolClock: Using Epigenetics to Measure The Biologi...

How OS-01 BODY Pauses Biological Aging For Overall...

Biohacking Healthy Aging: The Organs of Longevity

Does Niacinamide Help With Acne & Scarring?

5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...

6 Common In-Office Skin Treatments to Complement y...

What is Microneedling & Are There Alternatives?

How to Protect Against and Reverse Collagen Loss

Why Your Neck, Décolletage, and Hands Need Extra C...

What's the Connection Between Dehydration and Dry ...

How to Tighten Facial Skin Without Surgery

Exploring Alternatives to Botox

Best Practices for Moisturizing After Exfoliating

Recognizing Signs of Over-Exfoliated Skin

Healing Over-Exfoliated Skin: How to Treat Over-Ex...

OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...

Introducing OS-01 BODY SPF: Triple power protectio...

Is Talc Bad for Skin? 7 Things You Need to Know

How Do We Know the OS-01 Peptide is Safe?

What Is Lanolin and Is It Bad for Your Skin?

Non-Comedogenic vs Comedogenic Skin Care Products

Mineral Oil: Facts, Myths, and Effects on Skin

The Problem with Paraffin for Skin

Petrolatum: Is it Safe or Harmful for Your Skin?

How Much Sunscreen to Apply

What Do Antioxidants Do For Skin and Why Should Yo...

Making Sense of SPFs: What’s the Difference Betwee...

How to Relieve Itchy Skin: Tips for Soothing Skin ...

What is The Difference Between UVA and UVB Rays?

Decoding the Connections Between Intrinsic & Extri...

Causes of Skin Itching: Understanding the Reasons ...

How to Protect Your Skin from UVA and UVB Rays

Morning vs. Night Exfoliation: Determining the Bes...

How to Tell if Acne is Hormonal or Bacterial?

How to Know if Your Skin Barrier is Damaged

Tips for Managing Hormonal Breakouts

Understanding Hormonal Acne and Its Triggers

How to Repair & Restore Your Skin Barrier

How To Get Rid of Crepey Skin: 7 Solutions

When to Apply Sunscreen: Before or After Moisturiz...

How Alcohol Impacts Your Skin’s Health

The Effects of Alcohol on Your Skin's Aging Proces...

OS-01 FACE: Clinically Validated to Support Your S...

Can Alcohol Cause Breakouts?

The Proof is in the Peptide: 12-Week Clinical Stud...

Why Is My Neck Aging So Fast?

6 Factors That Contribute to Slow Skin Healing

6 Tips and Tricks for a Youthful Neck

Addressing the Need for Indoor Sun Protection

The Science of Sunburns: How to Treat and Prevent ...

Get to Know OneSkin’s Topical Supplements:
OS-01 F...

Can Air Quality Affect Skin? Exploring the Impact ...

Understanding the Relationship Between Sleep and U...

Exploring the Effects of Quality Sleep on Your Ski...

How to Improve Gut Microbiome

Exploring Caloric Restriction and Its Effects on A...

What’s the Connection Between Quality Sleep and Lo...

Unlocking the Skin Benefits of Intermittent Fastin...

Why Exercise is a Game-Changer for Longevity

The Microbiome Diet and Its Effects on Skin

Cold Exposure: Hype or Longevity Boosting?

Eat Better, Live Longer: Top Foods for Longevity

How to Protect Your Skin from Everyday Environment...

How Does Sunscreen Work? How Long Does it Last?

Pressing the Pause Button on Aging Skin: OS-01 BOD...

What Causes Dark Circles Under and Around Your Eye...

How to Brighten Eyes and Under-Eyes

Lip Balm Ingredients: What to Look for and What to...

Exploring Blue Zones: How Can We Optimize Our Heal...

Nurturing Your Lips: How to Keep Them Moisturized ...

Uncovering the 9 Causes of Dry Lips: Why Do Lips G...

How to Travel with Skin Care Products

Why is my Skin Peeling on My Face?

The Importance of Sunscreen: Why Should You Wear I...

Lip Sunscreen: Do Lips Need SPF Protection?

The Science of Gratitude

Removing Sunscreen: Tips for Clean and Healthy Ski...

Skin Explained: Is Skin An Organ?

UV Light and Skin: Effects and Protection Strategi...

Understanding The Epidermis: Functions, Compositio...

Diving into Dermis: Functions and Significance

Unlocking the Science of Wrinkles: Causes, Formati...

PREP enhances the effects of OS-01 FACE, and the p...

Why Skin Barrier is Important

Ingredient Spotlight: Bentonite Uses, Benefits, & ...

Hypodermis: Exploring Its Vital Functions

oil-dropper-background-pink-dripping-cosmetic-product

The EU is Limiting Retinol in Skincare: Here’s Eve...

Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...

Ceramides For Skin: Everything You Need to Know ne...

Age Gracefully: How to Manage Neck Wrinkles and Ac...

Discover Why Our New SPF Outperforms the Rest

How to Preserve Your Feet: 5 Strategies for Wrinkl...

Hands and Dermal Elasticity: Understanding and Man...

The Lip Lineage: Exploring the Why Behind Wrinkled...

How to Address Stomach Wrinkles For Smoother Skin

A Scientific Approach to Addressing Wrinkly Skin o...

What is Skin Cycling? Understanding, Embracing, an...

How to Skin Cycle: A Guide to Optimize Your Skin C...

Do You Know What Clinical Claims Really Mean?

What is Tinted Sunscreen?

2 Types of Wrinkles and Tips for Treating Them

Understanding Marionette Lines: Causes and Prevent...

How to Help Your Skin Act Younger

The Science of Sunscreen: Understanding the Optima...

Better Elasticity, More Firmness: Discover OS-01 E...

Symptoms and Causes of Melasma on Face

How to Prevent Skin Aging Before It Starts

A Comprehensive Guide to Understanding the Differe...

How to Strengthen Your Skin: A Guide to Thicker, H...

An In-Depth Look at Glycerin: What is it and What ...

Exploring the Benefits of Glycerin for Skin Health

Difference Between Hydrating and Moisturizing

Exploring the Difference Between Hydrating and Moi...

3 Natural Ways to Keep Your Skin Hydrated and Glow...

How To Create A Hydrating Skin Care Routine For Dr...

Senotherapeutics, Senolytics, and Senomorphics -- ...

Cleansing 101: How to Wash Your Face the Right Way...

Scientific Breakthrough: OneSkin’s scientists show...

Dry Skin 101: How To Identify This Skin Type

How OS-01 Can Help Your Collagen Levels As You Age...

Developing a Skin Care Routine for Normal Skin: 4 ...

What is Normal Skin & Do I Have This Skin Type?

A Step-by-Step Guide to Creating the Perfect Skin ...

Understanding Oily Skin: Causes & Characteristics

7 Keys to Understanding Menopause and Skin Changes

Is This The Root Cause of Aging?

UV Damage Increases Cellular Senescence. Here's Ho...

Our Research Has Been Published in npj Aging

How To Reduce Hyperpigmentation by Targeting Cellu...

Perfect Skin Care Routine for Combination Skin

4 Steps to Crafting the Perfect Skin Care Routine ...

A Comprehensive Guide to Understanding and Managin...

An In-Depth Look At The Benefits Of Moringa Oil Fo...

How to Tighten the Skin Under Your Eyes

7 Causes For Crepey Skin Under Eyes

101 Guide To Restoring Dry Skin Around The Eyes

How is OS-01 EYE different from OS-01 FACE?

How to Remove Lingering Dead Skin Cells On the Fac...

Safe Beauty, Validated: Why OneSkin trusts SkinSAF...

Hallmarks of Aging

What is Sensitive Skin?

How OS-01 Works on Mature Skin

Is Fragrance Bad for Your Skin?

Target Cellular Senescence with the Highest Concen...

Can a Plant-Based Diet Really Increase Your Health...

Eye Skin Ages Faster: Here’s How OS-01 Can Help

Gut Health and Skin: How Are They Connected?

The Science Behind Why The Skin Around the Eyes Ag...

How OS-01 EYE Supports the Ultra-Thin Skin Around ...

How Do You Know When to Stop Using Retinol?

How To Heal Skin From Picking Your Face Too Much

Collagen And Elastin: What Role Do They Play In Sk...

Why We Want Skin To Be More, Not Less

More Than Skin Deep: How Physical Touch Predicts L...

What is Skin Inflammation? What Causes it?

How to Reverse (or Prevent) Aging Skin

Yes, You Need Sunscreen During Winter

Can You Use Hyaluronic Acid with Retinol?

Exploring the skin’s purpose in whole-body health

Stressed Skin: 4 Stress Effects on the Skin

What Does Hyaluronic Acid Do For Your Skin?

Good Genes vs. Good Habits: Which Impacts Your Lon...

What Are The Causes Of Dry, Flaky Skin On Your Fac...

What is the Best Skin Care Regimen for Aging Skin?

7 Benefits of Jojoba Oil

What happens to skin as a person ages?

What are the Benefits of Sulforaphane?

8 Benefits of Andiroba Oil For Skin

Invasive vs. Non-Invasive Skincare: The pros and c...

Allantoin For Skin: A Comprehensive Guide

This is the Data to Look For When Choosing Skin Ca...

Why cellular senescence is more than just one of t...

A Simplified Guide To The Different Skin Texture T...

How OS-01 Works With Different Skin Types

How To Smooth Skin Texture On The Face: 4 Expert T...

Skin Microbiome: What It Is, Why it’s Important, A...

What Foods Cause Acne and Which Fight Against It?

The 101 Guide To Understanding Acne-Prone Skin

The Top 4 Prickly Pear Benefits for Skin

What Is Exfoliation & Is It A Necessary Measure Fo...

OneSkin Notable Mention: Dave Asprey's The Human U...

Clean Beauty: What “clean” really means and why “s...

Retinol 101: Debunking Retinol as the Gold Standar...

Menopause & Skin: What you need to know

Take an Inside Look into Our Cutting-Edge R&D Plat...

101 Guide On The Benefits Of Cleansing Your Face

Cleanser Vs. Face Wash: Which Should I Reach For?

Five Common Skin Problems Experienced in Perimenop...

Get to Know OneSkin’s Topical Supplements:

OS-

...

The Top 3 Benefits of Peptides for Skin

How to Use Peptides In Your Skincare Regimen to Op...

Peptides vs Retinol: Is One Better For Increasing ...

What Is Causing the Uneven Skin Tone On Your Body?

How To Boost Skin Moisture For Your Entire Body Fr...

Three Ways To Extend Your Skinspan Starting With Y...

What Are Free Radicals and How Do They Impact Skin...

The Top 6 Best Antioxidants For Skin Health and Lo...

How OneSkin Developed the OS-01 Peptide

How chronic stress makes you age faster

What is Epidermal Thickness & Why Does it Matter?

Cell Turnover & Why It Slows As We Age

OneSkin Notable Mention: OneSkin Featured In Tony ...

101 Guide To Skin Tightening + 7 Noninvasive Metho...

Tight Feeling Skin: 3 Reasons Why

3 Skin Tightening Ingredients To Help Boost Skin H...

How to Reduce Skin Inflammation & Redness

Niacinamide Vs Retinol: How Do They Compare?

How to Incorporate OneSkin’s OS-01 Topical Supplem...

Why Is Nutrient Absorption Key To Better Skin Heal...

OneSkin Notable Mention: LifeSpan Episode 6 | The ...

The Top 10 Best Foods for Skin Repair

Are There Dangers of Retinol Cream Use?

What is Skin Elasticity & How Can You Improve It?

A Complete Guide to the 4 Stages of Wound Healing

4 Foods To Avoid During Wound Healing & Why

Celebrating Black History Month: A Discussion With...

What is the Function of Skin as a Protective Barri...

Representation of the Black Community in Skin Care...

Our Story: Learn more about the history of OneSkin...

What Is Senescence & Its Relationship To Aging?

Winter Skincare - How To Prevent Dry Skin this Sea...

Special Announcement: OneSkin to Donate 1% of Sale...

Biological Age: What is Biological Age, Why Does i...

What your skincare routine is missing (Hint. It’s ...

What is a peptide?
Peptides: the first piece of th...

Health Is The New Wealth

Sleep: Nature’s Restart Button? - One Skin Technologies

The Correlation Between Sleep and Skin: Why It Mat...

How Relationships, Community, & Social Interaction...

Calorie Restriction And Intermittent Fasting: Eati...

Healthspan: A New Way To Think About Aging