The EU is Limiting Retinol in Skincare: Here’s Everything You Need to Know
3 min read
September 26,2023
INGREDIENTS
The EU is Limiting Retinol in Skincare: Here’s Everything You Need to Know
3 min read
September 26,2023
INGREDIENTS
The darling of dermatologists, retinol has long been considered one of the very best anti-aging ingredients. But a number of concerns–from toxicity during pregnancy to painful side effects–have made some experts question its accolades. Now, the EU’s consumer protection agency is voicing their own apprehensions. By the end of this year, the EU intends to limit retinol concentration to just 0.3% in face products and 0.05% in body products. (1) Here in the United States, many popular over-the-counter products contain retinol percentages up to 1%. So does this mean you should be more cautious with your retinol consumption? Let’s dig into the science to understand the EU’s decision – and what you can use instead to give your skin anti-aging benefits without the downsides.
The darling of dermatologists, retinol has long been considered one of the very best anti-aging ingredients. But a number of concerns–from toxicity during pregnancy to painful side effects–have made some experts question its accolades. Now, the EU’s consumer protection agency is voicing their own apprehensions. By the end of this year, the EU intends to limit retinol concentration to just 0.3% in face products and 0.05% in body products. (1) Here in the United States, many popular over-the-counter products contain retinol percentages up to 1%. So does this mean you should be more cautious with your retinol consumption? Let’s dig into the science to understand the EU’s decision – and what you can use instead to give your skin anti-aging benefits without the downsides.
01
What is retinol?
Retinol is a form of vitamin A – the most well-known member of a family of ingredients called retinoids. Retinoids come in a variety of forms including retinol, retinal, retinaldehyde, retinoic acid, tretinoin, retinyl palmitate, and retinyl acetate. When applied topically, retinoids encourage our skin cells to produce more collagen, which slowly thickens our epidermal layer. (2) Retinoids also compel cells in deeper skin layers to divide more frequently, allowing new cells to replace older cells at the surface. This accelerated skin cell turnover reduces the appearance of wrinkles, smooths out uneven skin texture and visibly brightens skin tone.
01
What is retinol?
Retinol is a form of vitamin A – the most well-known member of a family of ingredients called retinoids. Retinoids come in a variety of forms including retinol, retinal, retinaldehyde, retinoic acid, tretinoin, retinyl palmitate, and retinyl acetate. When applied topically, retinoids encourage our skin cells to produce more collagen, which slowly thickens our epidermal layer. (2) Retinoids also compel cells in deeper skin layers to divide more frequently, allowing new cells to replace older cells at the surface. This accelerated skin cell turnover reduces the appearance of wrinkles, smooths out uneven skin texture and visibly brightens skin tone.
02
Why is the EU limiting the concentration of retinol?
For years, the European Union’s Scientific Committee on Consumer Safety (SCCS) has raised concerns about retinol. Their main worry is that regular retinol usage could contribute to high levels of vitamin A in the bloodstream. While we need vitamin A to survive, too much vitamin A has been linked to a number of health concerns, including birth defects and liver dysfunction. The SCCS’s conclusion is that, without a restriction on cosmetic products, total exposure from personal care products, nutritional supplements and diet could exceed the upper limits recommended by the European Food Safety Authority (EFSA).
02
Why is the EU limiting the concentration of retinol?
For years, the European Union’s Scientific Committee on Consumer Safety (SCCS) has raised concerns about retinol. Their main worry is that regular retinol usage could contribute to high levels of vitamin A in the bloodstream. While we need vitamin A to survive, too much vitamin A has been linked to a number of health concerns, including birth defects and liver dysfunction. The SCCS’s conclusion is that, without a restriction on cosmetic products, total exposure from personal care products, nutritional supplements and diet could exceed the upper limits recommended by the European Food Safety Authority (EFSA).
03
Why are the EU’s restrictions different for body and face products?
The more skin surface area that’s treated with retinol, the higher the dose of vitamin A that the body receives. Because body products are used on larger areas of skin, they may contribute to higher levels of vitamin A in the bloodstream. By limiting the retinol concentration in body products to just 0.05%, the EU hopes to prevent higher concentrations of vitamin A from accumulating in the body.
03
Why are the EU’s restrictions different for body and face products?
The more skin surface area that’s treated with retinol, the higher the dose of vitamin A that the body receives. Because body products are used on larger areas of skin, they may contribute to higher levels of vitamin A in the bloodstream. By limiting the retinol concentration in body products to just 0.05%, the EU hopes to prevent higher concentrations of vitamin A from accumulating in the body.
04
Which countries will be affected by the restrictions?
In addition to all member countries of the EU, the restrictions will impact countries that belong to the European Economic Area European Free Trade Association: Iceland, Lichtenstein, Norway, and North Macedonia.
04
Which countries will be affected by the restrictions?
In addition to all member countries of the EU, the restrictions will impact countries that belong to the European Economic Area European Free Trade Association: Iceland, Lichtenstein, Norway, and North Macedonia.
05
Does this mean retinol is dangerous?
The EU’s decision does not necessarily indicate that retinol products are unsafe. In fact, you’re much more likely to get unsafe doses of vitamin A from food and supplements. However, because the SCCS’s purview does not include food and nutritional products, their ability to take action on their concerns only includes personal care products. The SCCS admits that their decision is meant to protect a very small percentage of the European population – just 5%-- who may be at risk of overexposure to vitamin A. That means the majority of people do not need to worry about retinol toxicity. (1) However, there may be other compelling reasons to ditch retinol from your routine. This notoriously sensitizing ingredient comes with a long rap sheet of potential side effects including skin peeling, redness, itchiness, and flaking. Plus, according to lab tests conducted by our scientific team, retinol might not actually be that good for your skin on the cellular level, at least in the acute phase.
05
Does this mean retinol is dangerous?
The EU’s decision does not necessarily indicate that retinol products are unsafe. In fact, you’re much more likely to get unsafe doses of vitamin A from food and supplements. However, because the SCCS’s purview does not include food and nutritional products, their ability to take action on their concerns only includes personal care products. The SCCS admits that their decision is meant to protect a very small percentage of the European population – just 5%-- who may be at risk of overexposure to vitamin A. That means the majority of people do not need to worry about retinol toxicity. (1) However, there may be other compelling reasons to ditch retinol from your routine. This notoriously sensitizing ingredient comes with a long rap sheet of potential side effects including skin peeling, redness, itchiness, and flaking. Plus, according to lab tests conducted by our scientific team, retinol might not actually be that good for your skin on the cellular level, at least in the acute phase.
06
What does the cellular data on retinol show?
Our scientists here at OneSkin conducted an expression analysis to observe how retinol impacts biomarkers associated with skin aging, cellular proliferation, and collagen production. The results show that retinol may not be the anti-aging silver bullet we once thought it was. Our tests showed that although retinol significantly increases a key biomarker associated with collagen production (COL1A1), it also created a tenfold increase in a biomarker linked to aging (CDKN2A). So while retinol does effectively boost collagen production, it may come at a cost: increased aging activity. (3) It should be noted, however, that this data was collected after 5 days of exposure, therefore it represents the acute effects of retinol on skin.
06
What does the cellular data on retinol show?
Our scientists here at OneSkin conducted an expression analysis to observe how retinol impacts biomarkers associated with skin aging, cellular proliferation, and collagen production. The results show that retinol may not be the anti-aging silver bullet we once thought it was. Our tests showed that although retinol significantly increases a key biomarker associated with collagen production (COL1A1), it also created a tenfold increase in a biomarker linked to aging (CDKN2A). So while retinol does effectively boost collagen production, it may come at a cost: increased aging activity. (3) It should be noted, however, that this data was collected after 5 days of exposure, therefore it represents the acute effects of retinol on skin.
Shown in ex vivo human skin samples (35, 55, and 79 yr) topically treated with the OS-01 FACE formula and 1% retinol for 5 days, then analyzed according to mRNA expression of key aging and skin health related biomarkers (CDKN2A aging, COL1A1 collagen production, and MKi67 proliferation). (Zonari, A, et al, npj Aging, 2023 Supplementary Information)
Shown in ex vivo human skin samples (35, 55, and 79 yr) topically treated with the OS-01 FACE formula and 1% retinol for 5 days, then analyzed according to mRNA expression of key aging and skin health related biomarkers (CDKN2A aging, COL1A1 collagen production, and MKi67 proliferation). (Zonari, A, et al, npj Aging, 2023 Supplementary Information)
07
What can I use instead?
If you are sensitive to retinol, can't use it for any reason, or looking for a complementary product, OS-01 FACE may represent a good alternative or addition to retinol. When compared to retinol at the cellular level, our flagship product, OS-01 FACE, provides similar benefits with none of the drawbacks. Like retinol, OS-01 FACE significantly increases a key biomarker associated with collagen production (COL1A1). However, OS-01 FACE doesn’t impact that same biomarker associated with aging that retinol increases (CDKN2A). Plus, OS-01 FACE significantly increases a key biomarker associated with cell proliferation, MKi67, while retinol does not, indicating that OS-01 FACE could be more effective at promoting cell proliferation in the skin. (4) This comparison shows that OS-01 FACE works to boost collagen and cell proliferation without the aging downsides associated with retinol. It should be noted, that this data was collected after 5 days of exposure and therefore represents the acute effects on each treatment on skin. Regardless, OS-01 FACE is clinically validated to boost skin's barrier and hydration, making it a good complement to retinol as it may help alleviate some of the acute irritation and sensitivity that retinol causes. (3,5)
07
What can I use instead?
If you are sensitive to retinol, can't use it for any reason, or looking for a complementary product, OS-01 FACE may represent a good alternative or addition to retinol. When compared to retinol at the cellular level, our flagship product, OS-01 FACE, provides similar benefits with none of the drawbacks. Like retinol, OS-01 FACE significantly increases a key biomarker associated with collagen production (COL1A1). However, OS-01 FACE doesn’t impact that same biomarker associated with aging that retinol increases (CDKN2A). Plus, OS-01 FACE significantly increases a key biomarker associated with cell proliferation, MKi67, while retinol does not, indicating that OS-01 FACE could be more effective at promoting cell proliferation in the skin. (4) This comparison shows that OS-01 FACE works to boost collagen and cell proliferation without the aging downsides associated with retinol. It should be noted, that this data was collected after 5 days of exposure and therefore represents the acute effects on each treatment on skin. Regardless, OS-01 FACE is clinically validated to boost skin's barrier and hydration, making it a good complement to retinol as it may help alleviate some of the acute irritation and sensitivity that retinol causes. (3,5)
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Key Takeaways:
- By the end of this year, the EU will restrict retinol concentration in topical products due to concerns that higher concentrations could lead to vitamin A toxicity.
- Restrictions will be more stringent for body products because a larger treatment area means a higher chance of too much vitamin A entering the bloodstream.
- This restriction doesn’t necessarily mean retinol is unsafe. In fact, the decision reflects a concern that, according to the EU’s consumer protection agency, impacts only a very small percentage of the European population.
- However, there may be other reasons to limit your retinol usage: in lab studies, it has been shown to increase aging biomarkers in the acute phase over 5 days.
- OneSkin’s flagship product, OS-01 FACE, offers similar molecular benefits as retinol without increasing aging biomarkers, plus it's gentle on skin and builds the skin barrier. OS-01 FACE can be used as a retinol alternative for those sensitive to retinol, or as a complementary product to counteract some of retinol's potentially harsh effects.
Key Takeaways:
- By the end of this year, the EU will restrict retinol concentration in topical products due to concerns that higher concentrations could lead to vitamin A toxicity.
- Restrictions will be more stringent for body products because a larger treatment area means a higher chance of too much vitamin A entering the bloodstream.
- This restriction doesn’t necessarily mean retinol is unsafe. In fact, the decision reflects a concern that, according to the EU’s consumer protection agency, impacts only a very small percentage of the European population.
- However, there may be other reasons to limit your retinol usage: in lab studies, it has been shown to increase aging biomarkers in the acute phase over 5 days.
- OneSkin’s flagship product, OS-01 FACE, offers similar molecular benefits as retinol without increasing aging biomarkers, plus it's gentle on skin and builds the skin barrier. OS-01 FACE can be used as a retinol alternative for those sensitive to retinol, or as a complementary product to counteract some of retinol's potentially harsh effects.
References
- https://www.drrachelho.com/blog/retinol-restriction-europe-2024
- https://pubmed.ncbi.nlm.nih.gov/26578346/#:~text=Results%3A%30Four%20weeks%20of%20retinoic.and%procollagen%20llll%20protein%20expression
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging 9(1). 1-15. 2023.
- https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16242
References
- https://www.drrachelho.com/blog/retinol-restriction-europe-2024
- https://pubmed.ncbi.nlm.nih.gov/26578346/#:~text=Results%3A%30Four%20weeks%20of%20retinoic.and%procollagen%20llll%20protein%20expression
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging 9(1). 1-15. 2023.
- https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16242
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
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The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging