What happens to skin as a person ages?
6 min read
THE ONESKIN TEAM
December 15,2022
LONGEVITY, SKIN SCIENCE
What happens to skin as a person ages?
6 min read
THE ONESKIN TEAM
December 15,2022
LONGEVITY, SKIN SCIENCE
As the body’s largest organ, skin plays a critical role in our protection, regulation, and sensation. Skin is the body’s first defense against the external world, shielding us from harmful environmental factors such as UV rays, pollution, pathogens, and physical dangers. Skin also plays a critical role in maintaining homeostasis, including water retention, temperature regulation, and vitamin synthesis. And, of great importance to our survival, skin provides our bodies with sensations required to make key instinctual decisions.
As the body’s largest organ, skin plays a critical role in our protection, regulation, and sensation. Skin is the body’s first defense against the external world, shielding us from harmful environmental factors such as UV rays, pollution, pathogens, and physical dangers. Skin also plays a critical role in maintaining homeostasis, including water retention, temperature regulation, and vitamin synthesis. And, of great importance to our survival, skin provides our bodies with sensations required to make key instinctual decisions.
But what ages skin? As our cells naturally age and are exposed to daily harsh elements, skin can accumulate damage at the cellular level. These intrinsic and extrinsic aging factors cause skin to deteriorate and become less effective at performing its crucial protective, regulatory, and sensory functions. Visually, these effects can be observed by a loss in skin strength, texture, and tone – all physical signs of extrinsic or intrinsic aging that should not be taken lightly, as they can point to an underlying loss of skin health and function.So how do we identify skin aging and can we take steps to slow down this process? This blog will discuss what happens to a person's skin as they age, including the signs of aging skin and factors that can accelerate or hinder the process of skin aging.
But what ages skin? As our cells naturally age and are exposed to daily harsh elements, skin can accumulate damage at the cellular level. These intrinsic and extrinsic aging factors cause skin to deteriorate and become less effective at performing its crucial protective, regulatory, and sensory functions. Visually, these effects can be observed by a loss in skin strength, texture, and tone – all physical signs of extrinsic or intrinsic aging that should not be taken lightly, as they can point to an underlying loss of skin health and function.So how do we identify skin aging and can we take steps to slow down this process? This blog will discuss what happens to a person's skin as they age, including the signs of aging skin and factors that can accelerate or hinder the process of skin aging.
01
What happens to skin as we grow older?
Loss of collagen and elastinA characteristic feature of older skin is the progressive loss of the primary structural and functional proteins in the skin: collagen and elastin. Collagen promotes skin firmness while elastin enables skin rebound and elasticity, and these proteins work in concert to enable skin resilience and provide a fresh, smooth appearance. While the production of these essential structural proteins naturally decline with age [1], especially during menopause [2], the rate of decline with age can be greatly accelerated by both internal and environmental stressors, such as UV exposure, mental stress, poor diet, and smoking [3]. When skin cells are broken down from these stressors, the fragmented proteins can accumulate in the skin and inhibit the ability of skin cells to regenerate new collagen and elastin [1].Reduced moisture retentionOlder skin also exhibits reduced moisture retention due to loss in structural integrity and lower production of moisture-retaining molecules. One such molecule is hyaluronic acid, an essential compound produced in the skin that has a uniquely robust capacity to bind and retain water in the skin. Like collagen and elastin, production of hyaluronic acid significantly reduces with age and as a result of damage accumulation. Declining levels of hydrating molecules like hyaluronic acid in the skin can lead to compromised skin structure and barrier function [4].Less fat and diminished bone structureAdditional age-associated changes in skin can also be attributed to the loss of fat, cartilage, and bone structure in the layers below the skin, particularly the chin, cheeks, eyes, and nose. This may result in sunken eyes, loose skin, and puckering areas. These physical effects can be exacerbated by excess weight loss or gain, facial movements, sleeping position, and gravity.
01
What happens to skin as we grow older?
Loss of collagen and elastinA characteristic feature of older skin is the progressive loss of the primary structural and functional proteins in the skin: collagen and elastin. Collagen promotes skin firmness while elastin enables skin rebound and elasticity, and these proteins work in concert to enable skin resilience and provide a fresh, smooth appearance. While the production of these essential structural proteins naturally decline with age [1], especially during menopause [2], the rate of decline with age can be greatly accelerated by both internal and environmental stressors, such as UV exposure, mental stress, poor diet, and smoking [3]. When skin cells are broken down from these stressors, the fragmented proteins can accumulate in the skin and inhibit the ability of skin cells to regenerate new collagen and elastin [1].Reduced moisture retentionOlder skin also exhibits reduced moisture retention due to loss in structural integrity and lower production of moisture-retaining molecules. One such molecule is hyaluronic acid, an essential compound produced in the skin that has a uniquely robust capacity to bind and retain water in the skin. Like collagen and elastin, production of hyaluronic acid significantly reduces with age and as a result of damage accumulation. Declining levels of hydrating molecules like hyaluronic acid in the skin can lead to compromised skin structure and barrier function [4].Less fat and diminished bone structureAdditional age-associated changes in skin can also be attributed to the loss of fat, cartilage, and bone structure in the layers below the skin, particularly the chin, cheeks, eyes, and nose. This may result in sunken eyes, loose skin, and puckering areas. These physical effects can be exacerbated by excess weight loss or gain, facial movements, sleeping position, and gravity.
02
What are the 3 main visible signs of aging?
While there are numerous signs of skin aging, here are a few of the most common:1. FragilityThe structural integrity of the skin layers often becomes compromised with age due to the flattening and thinning of layers between the dermis and epidermis. This is caused by the loss of mass in the fat pad beneath the skin’s surface. This subsequent fragility, as well as the thinning of blood vessel walls, can result in easy bruising and development of skin damage, lesions, and skin cancer [5].2. Loss in elasticityElasticity in the skin is reduced with age due to the degradation of structural proteins, especially elastin and collagen. Skin thickness and cell turnover also decreases by approximately 6% per decade [5]. This can lead to loosely-hanging skin, reduced facial structure, less effective moisture retention, and increased presence of fine lines and wrinkles.3. TransparencyAs skin ages, it loses the ability to maintain robust skin cell shape and efficient regeneration. This is especially true for pigment-producing cells called melanocytes. Melanocytes decrease by up to 20% per decade, contributing to uneven pigmentation with age. Reduced cellular turnover leads to thinning of the skin and loss of facial tone, which can cause transparency [6].
02
What are the 3 main visible signs of aging?
While there are numerous signs of skin aging, here are a few of the most common:1. FragilityThe structural integrity of the skin layers often becomes compromised with age due to the flattening and thinning of layers between the dermis and epidermis. This is caused by the loss of mass in the fat pad beneath the skin’s surface. This subsequent fragility, as well as the thinning of blood vessel walls, can result in easy bruising and development of skin damage, lesions, and skin cancer [5].2. Loss in elasticityElasticity in the skin is reduced with age due to the degradation of structural proteins, especially elastin and collagen. Skin thickness and cell turnover also decreases by approximately 6% per decade [5]. This can lead to loosely-hanging skin, reduced facial structure, less effective moisture retention, and increased presence of fine lines and wrinkles.3. TransparencyAs skin ages, it loses the ability to maintain robust skin cell shape and efficient regeneration. This is especially true for pigment-producing cells called melanocytes. Melanocytes decrease by up to 20% per decade, contributing to uneven pigmentation with age. Reduced cellular turnover leads to thinning of the skin and loss of facial tone, which can cause transparency [6].
03
How do you know if your skin is aging?
Aside from lines and wrinkles, most of these deleterious changes alter the structure and biochemistry of the skin that affect injury repair, permeability, texture, and prevalence of skin disease.Thinning skin or presence of crepey skin is another key indicator of skin aging. Crepiness is caused by the decrease in epidermal thickness that comes with age and is particularly common in women on the face, neck, chest, and forearms [5]. Skin’s strength and elasticity is also reduced in aging and is accelerated with extreme sun damage, which can cause a weather-beaten appearance called elastosis [7].Significant pigmentation or color changes, including skin paling and transparency, is another key indication of aging. The combination of skin thinning and a decrease in the number of pigment-producing melanocytes can cause significant changes in skin tone that are commonly observed with age. Sun-exposed areas are especially prone to skin changes like pigmentation, including the development of lentigo maligna or “liver spots.”Finally, aged skin is often very dry due to the low production of hyaluronic acid and the decreased production of facial sebum–a combination of oily lipids produced in the follicles to protect the skin's surface. Women gradually produce less sebum beginning after menopause through the age of 70, while men tend to produce less sebum after the age of 80 [8].
03
How do you know if your skin is aging?
Aside from lines and wrinkles, most of these deleterious changes alter the structure and biochemistry of the skin that affect injury repair, permeability, texture, and prevalence of skin disease.Thinning skin or presence of crepey skin is another key indicator of skin aging. Crepiness is caused by the decrease in epidermal thickness that comes with age and is particularly common in women on the face, neck, chest, and forearms [5]. Skin’s strength and elasticity is also reduced in aging and is accelerated with extreme sun damage, which can cause a weather-beaten appearance called elastosis [7].Significant pigmentation or color changes, including skin paling and transparency, is another key indication of aging. The combination of skin thinning and a decrease in the number of pigment-producing melanocytes can cause significant changes in skin tone that are commonly observed with age. Sun-exposed areas are especially prone to skin changes like pigmentation, including the development of lentigo maligna or “liver spots.”Finally, aged skin is often very dry due to the low production of hyaluronic acid and the decreased production of facial sebum–a combination of oily lipids produced in the follicles to protect the skin's surface. Women gradually produce less sebum beginning after menopause through the age of 70, while men tend to produce less sebum after the age of 80 [8].
04
What are some ways to slow the effects of skin aging?
Prioritizing UV protectionThe best known way to slow the effects of skin aging are with physical protection from UV rays and environmental irritants. Regular, year-round application of at least 30 SPF sun protection and avoiding tanning/sun exposure can help protect your skin at the cellular level from harmful UVA and UVB rays that greatly accelerate the skin aging process.Maintaining a healthy lifestyleStress, lack of sleep, and poor diet also have profound negative impacts on skin health due to their disruption of cellular growth and regeneration [9]. Proper rest and a healthy lifestyle promote skin cell maintenance. A diet with plenty of greens, grains, and lean protein can ensure proper levels of vitamins, trace elements, water, and protein, all of which contribute to optimal functioning skin cells [10].Following a proper skin care regimenMaintaining proper moisture levels with the regular use of topical skin care products, such as a gentle gel cleanser and peptide moisturizer can also promote healthy cell function. Adequate moisture retention helps promote proper skin cell performance and turnover, and clean skin ensures removal of dead skin cells that can inhibit product efficacy. Staying consistent with a specifically curated skin care regimen for aging skin that includes a gentle cleanser and a hydrating moisturizer, especially in drier climates and during the winter months, can combat excessive dryness and undue skin damage.Certain medications and tobacco use can cause premature aging in the skin due to decreased collagen synthesis and should be avoided whenever possible.
04
What are some ways to slow the effects of skin aging?
Prioritizing UV protectionThe best known way to slow the effects of skin aging are with physical protection from UV rays and environmental irritants. Regular, year-round application of at least 30 SPF sun protection and avoiding tanning/sun exposure can help protect your skin at the cellular level from harmful UVA and UVB rays that greatly accelerate the skin aging process.Maintaining a healthy lifestyleStress, lack of sleep, and poor diet also have profound negative impacts on skin health due to their disruption of cellular growth and regeneration [9]. Proper rest and a healthy lifestyle promote skin cell maintenance. A diet with plenty of greens, grains, and lean protein can ensure proper levels of vitamins, trace elements, water, and protein, all of which contribute to optimal functioning skin cells [10].Following a proper skin care regimenMaintaining proper moisture levels with the regular use of topical skin care products, such as a gentle gel cleanser and peptide moisturizer can also promote healthy cell function. Adequate moisture retention helps promote proper skin cell performance and turnover, and clean skin ensures removal of dead skin cells that can inhibit product efficacy. Staying consistent with a specifically curated skin care regimen for aging skin that includes a gentle cleanser and a hydrating moisturizer, especially in drier climates and during the winter months, can combat excessive dryness and undue skin damage.Certain medications and tobacco use can cause premature aging in the skin due to decreased collagen synthesis and should be avoided whenever possible.
05
At what age does skin start to thin?
Skin begins to thin when collagen levels decrease. Though the age at which collagen levels start to decline is based on skin type and varies from person to person, , this decline can begin as early as your twenties. On average, collagen production peaks in your late 20’s to early 30’s, with a gradual decline occurring throughout life [11]. However, other external factors, such as increased sun exposure and lifestyle choices, could cause earlier skin thinning.
05
At what age does skin start to thin?
Skin begins to thin when collagen levels decrease. Though the age at which collagen levels start to decline is based on skin type and varies from person to person, , this decline can begin as early as your twenties. On average, collagen production peaks in your late 20’s to early 30’s, with a gradual decline occurring throughout life [11]. However, other external factors, such as increased sun exposure and lifestyle choices, could cause earlier skin thinning.
06
How do you tell if your skin has lost its elasticity?
There are several methods to evaluate skin elasticity, which measure the ability of the skin to return to its original position. A common and easy method is the “Snap Test,” which can be performed by lightly pulling the skin underneath the eyes and observing how quickly it snaps back. Healthy skin snaps back immediately, while dehydrated or less elastic skin will take longer to return to its normal position. Similarly, the “Pinch Test” can be performed by pinching the skin on your arms, cheeks, and abdomen, with slowly-returning skin indicating a loss of elasticity.Close inspection of your skin in the mirror can also help identify loss of elasticity. Areas with recent changes in color, transparency, or firmness may be indications of aging skin. The presence of fine lines and wrinkles in the face and eyes are also obvious indications.
06
How do you tell if your skin has lost its elasticity?
There are several methods to evaluate skin elasticity, which measure the ability of the skin to return to its original position. A common and easy method is the “Snap Test,” which can be performed by lightly pulling the skin underneath the eyes and observing how quickly it snaps back. Healthy skin snaps back immediately, while dehydrated or less elastic skin will take longer to return to its normal position. Similarly, the “Pinch Test” can be performed by pinching the skin on your arms, cheeks, and abdomen, with slowly-returning skin indicating a loss of elasticity.Close inspection of your skin in the mirror can also help identify loss of elasticity. Areas with recent changes in color, transparency, or firmness may be indications of aging skin. The presence of fine lines and wrinkles in the face and eyes are also obvious indications.
07
Can skin's elasticity be restored?
Skin and longevity scientists have recently investigated the cellular causes of skin aging and identified ways to target and improve skin elasticity. In particular, the researchers at OneSkin have developed a peptide called OS-01 that is scientifically validated to promote the activity of key biomarkers associated with collagen and hyaluronic acid production, and cellular proliferation [12, 13]. The OS-01 peptide is also scientifically proven to aid in cellular repair and increase skin’s epidermal thickness [12, 13].OneSkin's line of topical supplements are powered by OS-01 and clinically validated to boost skin's barrier function, increase hydration, and improve skin's texture. OS-01 FACE and OS-01 EYE led to measurbale increases in skin's elasticity. Plus, OneSkin's SPFs target multiple aging pathways with the OS-01 peptide, potent antioxidants, and non-nano zinc oxide for broad-spectrum protection. [12, 13, 14]
07
Can skin's elasticity be restored?
Skin and longevity scientists have recently investigated the cellular causes of skin aging and identified ways to target and improve skin elasticity. In particular, the researchers at OneSkin have developed a peptide called OS-01 that is scientifically validated to promote the activity of key biomarkers associated with collagen and hyaluronic acid production, and cellular proliferation [12, 13]. The OS-01 peptide is also scientifically proven to aid in cellular repair and increase skin’s epidermal thickness [12, 13].OneSkin's line of topical supplements are powered by OS-01 and clinically validated to boost skin's barrier function, increase hydration, and improve skin's texture. OS-01 FACE and OS-01 EYE led to measurbale increases in skin's elasticity. Plus, OneSkin's SPFs target multiple aging pathways with the OS-01 peptide, potent antioxidants, and non-nano zinc oxide for broad-spectrum protection. [12, 13, 14]
Related Products
Related Products
Key Takeaways:
- Our skin has tremendous protective and homeostatic capabilities that progressively wane due to damage and natural degradation during aging.
- Collagen and elastin within the skin barrier provide strength, elasticity, and texture but can be compromised due to external exposures such as UV rays, pollution, pathogens, and physical dangers.
- A compromised skin barrier and changes to the underlying fat and bone can reduce the skin’s function and structure, ultimately leading to dry and fragile skin with a saggy, transparent appearance.
- Skin aging can be delayed by the use of sun protection, a healthy diet, a proper cleaning and moisturizing regimen, and other lifestyle adjustments.
- Additionally, scientists at OneSkin have developed a novel peptide, which is scientifically proven to reverse the effects of aging in the skin at the cellular level. The OS-01 peptide is able to promote the production of collagen and hyaluronic acid to improve skin texture, thickness, and reduced visible signs of aging. [12, 13, 14]
Key Takeaways:
- Our skin has tremendous protective and homeostatic capabilities that progressively wane due to damage and natural degradation during aging.
- Collagen and elastin within the skin barrier provide strength, elasticity, and texture but can be compromised due to external exposures such as UV rays, pollution, pathogens, and physical dangers.
- A compromised skin barrier and changes to the underlying fat and bone can reduce the skin’s function and structure, ultimately leading to dry and fragile skin with a saggy, transparent appearance.
- Skin aging can be delayed by the use of sun protection, a healthy diet, a proper cleaning and moisturizing regimen, and other lifestyle adjustments.
- Additionally, scientists at OneSkin have developed a novel peptide, which is scientifically proven to reverse the effects of aging in the skin at the cellular level. The OS-01 peptide is able to promote the production of collagen and hyaluronic acid to improve skin texture, thickness, and reduced visible signs of aging. [12, 13, 14]
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606623/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859014/
- https://www.mdpi.com/2079-9284/5/1/14
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886/
- https://pubmed.ncbi.nlm.nih.gov/16221138/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840548/
- https://pubmed.ncbi.nlm.nih.gov/30052192/
- https://link.springer.com/referenceworkentry/10.1007/978-3-662-47398-6_4
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146365/
- https://pubmed.ncbi.nlm.nih.gov/27144559/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151092/
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1606623/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7859014/
- https://www.mdpi.com/2079-9284/5/1/14
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886/
- https://pubmed.ncbi.nlm.nih.gov/16221138/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840548/
- https://pubmed.ncbi.nlm.nih.gov/30052192/
- https://link.springer.com/referenceworkentry/10.1007/978-3-662-47398-6_4
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146365/
- https://pubmed.ncbi.nlm.nih.gov/27144559/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1151092/
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Discover More
How To Turn Your Skin Care Resolutions Into Skin C...
What Does Clean Beauty Mean, And Why Does Safe Bea...
Winter Skincare - How To Prevent Dry Skin this Sea...
What Are Chemical Peels & Are There Alternatives?
How Relationships, Community, & Social Interaction...
Hair Loss 101: Combing Through the Science of Hair...
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
Peptides: The First Piece Of The Skin Longevity Pu...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
Discover More
How To Turn Your Skin Care Resolutions Into Skin C...
What Does Clean Beauty Mean, And Why Does Safe Bea...
Winter Skincare - How To Prevent Dry Skin this Sea...
What Are Chemical Peels & Are There Alternatives?
How Relationships, Community, & Social Interaction...
Hair Loss 101: Combing Through the Science of Hair...
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
Peptides: The First Piece Of The Skin Longevity Pu...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging