Meet OS-01, the first ingredient scientifically proven to reverse skin’s biological age.01, 02, 03
Meet OS-01, the first ingredient scientifically proven to reverse skin’s biological age.01, 02, 03
skin close up with freckles - clavivle

The real proof? It's in the numbers

7+

Years of Research

900+

Peptides Screened
18+

Patents + Publications

9,000+

5-Star
Reviews

skin close up with freckles - clavivle

The real proof? It's in the numbers

7+

Years of Research

900+
Peptides Screened

18+

Patents + Publications

9,000+

5-Star
Reviews

Results that go
beyond the lab
KIMBERLY W - **Nothing** has made the visible difference that OneSkin has! I'm on week 4 and I'm hooked! I might be able to avoid the more costly (money and time) procedure after all. 5 stars - os-01 face
LINDA B. - "I cannot believe how good and fast this works! I can see amazing results after only 8 days, using twice a day. I had deep crow's feet from hooded eyes and now the crow's feet are starting to flatten out, almost disappearing. When I say it actually works, it's not just maybe it looks a little better, I can definitely see a big difference." - 5 stars - OS-01 EYE
before and after - mens forehead
LYNN R. - "I really like this face wash. [PREP] has helped improve the texture of my skin and reduce large or clogged pores. Combined with the skin cream it is a very easy face regime that doesn't take too much time and effort. Love what it does for my skin." - 5 stars - PREP
BARBARA L. "I have only been using
OS-01 BODY for about one month now and I am shocked at the results!
The crepiness on my lower stomach and my upper arms has improved greatly. I am actually going to start wearing sleeveless dresses again!" - 5 stars - OS-01 BODY
neck before and after - woman

Results that go
beyond the lab

KIMBERLY W - **Nothing** has made the visible difference that OneSkin has! I'm on week 4 and I'm hooked! I might be able to avoid the more costly (money and time) procedure after all. 5 stars - os-01 face
LINDA B. - "I cannot believe how good and fast this works! I can see amazing results after only 8 days, using twice a day. I had deep crow's feet from hooded eyes and now the crow's feet are starting to flatten out, almost disappearing. When I say it actually works, it's not just maybe it looks a little better, I can definitely see a big difference." - 5 stars - OS-01 EYE
before and after - mens forehead
LYNN R. - "I really like this face wash. [PREP] has helped improve the texture of my skin and reduce large or clogged pores. Combined with the skin cream it is a very easy face regime that doesn't take too much time and effort. Love what it does for my skin." - 5 stars - PREP
BARBARA L. "I have only been using
OS-01 BODY for about one month now and I am shocked at the results!
The crepiness on my lower stomach and my upper arms has improved greatly. I am actually going to start wearing sleeveless dresses again!" - 5 stars - OS-01 BODY
neck before and after - woman
Meet the founders
What happens when 4 PhDs in immunology, skin regeneration, bioinformatics, and molecular biology challenge the “anti-aging” skin care industry?
founders on grey background
Meet the founders
What happens when 4 PhDs in immunology, skin regeneration, bioinformatics, and molecular biology challenge the “anti-aging” skin care industry?
Propelled by a shared mission to change the way humans experience aging.
We donate 0.5% of sales to the Aging Forward (formerly Shepherd's Center of America), which provides enriching opportunities for lifelong learning, volunteer service, healthy living, and community connections - all of the things that give life meaning. 
Aging Forward - formerly Shepherd's Center of America
Propelled by a shared mission to change the way humans experience aging.
We donate 0.5% of sales to the Aging Forward (formerly Shepherd's Center of America), which provides enriching opportunities for lifelong learning, volunteer service, healthy living, and community connections - all of the things that give life meaning. 
Aging Forward - formerly Shepherd's Center of America

Frequently Asked Questions


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Peptides are short chains of amino acids. They represent a broad class of molecules with many jobs, from forming the building blocks of larger proteins to acting as cellular messengers. Peptides found naturally in the body (called endogenous peptides), play a crucial role in tissue growth, hormone regulation, and other biological processes.
Exogenous peptides, which can be injected, ingested or delivered topically like OS-01, can send out signals to skin cells to trigger collagen and hyaluronic acid production, aid in cellular repair, and help strengthen the skin barrier.01,02,03

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Frequently Asked Questions


Chevron up
Peptides are short chains of amino acids. They represent a broad class of molecules with many jobs, from forming the building blocks of larger proteins to acting as cellular messengers. Peptides found naturally in the body (called endogenous peptides), play a crucial role in tissue growth, hormone regulation, and other biological processes.
Exogenous peptides, which can be injected, ingested or delivered topically like OS-01, can send out signals to skin cells to trigger collagen and hyaluronic acid production, aid in cellular repair, and help strengthen the skin barrier.01,02,03

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01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at
oneskin.co/claims
02
Zonari, A., et al. npj Aging, 2023
03
Zonari, A., et al. Journal of Cosmetic Dermatology, 2024

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at
oneskin.co/claims
02
Zonari, A., et al. npj Aging, 2023
03
Zonari, A., et al. Journal of Cosmetic Dermatology, 2024