How to Use Peptides In Your Skincare Regimen to Optimize Your Health
3 min read
MAY 16, 2022 - BY THE ONESKIN TEAM
May 16,2022
SKIN SCIENCE
How to Use Peptides In Your Skincare Regimen to Optimize Your Health
3 min read
MAY 16, 2022 - BY THE ONESKIN TEAM
May 16,2022
SKIN SCIENCE
Peptides are much more than the latest skincare craze, they can be the real deal! Peptides are critical in regulating your biological processes and ensuring optimal cell function, which is why peptides can make such an incredible impact on your skin cells when applied topically. Keep reading to learn the answers to the most commonly asked questions, such as “What is a peptide?” and “How can I incorporate peptides into my skincare regimen?”.
Peptides are much more than the latest skincare craze, they can be the real deal! Peptides are critical in regulating your biological processes and ensuring optimal cell function, which is why peptides can make such an incredible impact on your skin cells when applied topically. Keep reading to learn the answers to the most commonly asked questions, such as “What is a peptide?” and “How can I incorporate peptides into my skincare regimen?”.
01
What are Peptides?
Peptides and proteins are both made of amino acids. Think of amino acids like the “building blocks” of the peptides and proteins in your body. The differnece between peptides and proteins is their size and complexity. Peptides are generally short chains of two or more amino acids, while proteins are larger molecules made up of multiple peptide subunits. [1]There are many types of peptides, a few of which are llisted below: [1]
- Carrier peptides to facilitate the transport of other molecules.
- Signaling peptides to communicate in and between cells, often triggereing a biological response.
- Enzymes to catalyze a biological reaction.
01
What are Peptides?
Peptides and proteins are both made of amino acids. Think of amino acids like the “building blocks” of the peptides and proteins in your body. The differnece between peptides and proteins is their size and complexity. Peptides are generally short chains of two or more amino acids, while proteins are larger molecules made up of multiple peptide subunits. [1]There are many types of peptides, a few of which are llisted below: [1]
- Carrier peptides to facilitate the transport of other molecules.
- Signaling peptides to communicate in and between cells, often triggereing a biological response.
- Enzymes to catalyze a biological reaction.
02
How should peptides be used as part of your skin care routine?
Considering the significant benefits of peptides and their ability to induce profound changes in your skin, incorporating sceintifically-backed peptides into regimen should be strongly considered. When navigating how to use peptides in skincare, it’s important to note that they can be incorporated into your routine through two different routes: orally or topically.
02
How should peptides be used as part of your skin care routine?
Considering the significant benefits of peptides and their ability to induce profound changes in your skin, incorporating sceintifically-backed peptides into regimen should be strongly considered. When navigating how to use peptides in skincare, it’s important to note that they can be incorporated into your routine through two different routes: orally or topically.
03
Oral Peptide Supplements
Nutrition plays a fundamental role in the health of all your bodily systems, including your integumentary system – your skin. Peptides, being the building blocks of all living things, are first and foremost present in foods, especially the following protein-heavy foods. [2]
- Eggs
- Meat
- Fish and shellfish
- Beans and lentils
- Hemp seeds
- Wheat
- Increased skin hydration after 8 weeks
- Enhanced collagen density in the skin after 4 weeks
- Improvements remained even after 12 weeks of using peptide supplements
03
Oral Peptide Supplements
Nutrition plays a fundamental role in the health of all your bodily systems, including your integumentary system – your skin. Peptides, being the building blocks of all living things, are first and foremost present in foods, especially the following protein-heavy foods. [2]
- Eggs
- Meat
- Fish and shellfish
- Beans and lentils
- Hemp seeds
- Wheat
- Increased skin hydration after 8 weeks
- Enhanced collagen density in the skin after 4 weeks
- Improvements remained even after 12 weeks of using peptide supplements
04
Topical Peptides
Because of their size, scientifically-proven peptides make excellent ingredients in topical skin care products. Their minute size enables them to penetrate the skin into areas where other ingredients would simply sit atop the skin barrier, whether in face wash, mask, cream, or serum form. Peptides can sink into the skin, encouraging the production of collagen and elastin in deeper layers. Numerous studies indicate that topical peptides can improve skin texture, strengthen skin barrier, prevent and target photodamage, and diminish scars. It’s important to note, however, that not all peptides are made equal and some are larger than others with diminished penetration abilities. Therefore, peptides contained in skin care products should be tested for their ability to penetrate the skin’s deepest layers, along withtheir impact on teh cellular and tissue levels. [4,5,6]
04
Topical Peptides
Because of their size, scientifically-proven peptides make excellent ingredients in topical skin care products. Their minute size enables them to penetrate the skin into areas where other ingredients would simply sit atop the skin barrier, whether in face wash, mask, cream, or serum form. Peptides can sink into the skin, encouraging the production of collagen and elastin in deeper layers. Numerous studies indicate that topical peptides can improve skin texture, strengthen skin barrier, prevent and target photodamage, and diminish scars. It’s important to note, however, that not all peptides are made equal and some are larger than others with diminished penetration abilities. Therefore, peptides contained in skin care products should be tested for their ability to penetrate the skin’s deepest layers, along withtheir impact on teh cellular and tissue levels. [4,5,6]
Related Products
Related Products
05
How often should you use topical peptides?
The recommended frequency of use for a topical peptide as part of your skin care routine ultimately depends on your preferences, the manufacturer’s directions, and your skin type. For gentle products like OneSkin's OS-01 Topical Supplements, a twice-a-day application works best, typically in the morning and at night. [4,5,6]
05
How often should you use topical peptides?
The recommended frequency of use for a topical peptide as part of your skin care routine ultimately depends on your preferences, the manufacturer’s directions, and your skin type. For gentle products like OneSkin's OS-01 Topical Supplements, a twice-a-day application works best, typically in the morning and at night. [4,5,6]
06
Do topical peptides pair well with other ingredients used in your skin care regimen?
You’ll be happy to hear that peptide products typically pair well with most other skin care products. Unlike other ingredients, peptides generally don’t strip the skin or neutralize other ingredients. Peptides tend to work excellently alongside other ingredients, like hyaluronic acids and vitamin C. Additionally, you may consider pairing harsh skin products, such as retinol, with the use of a peptide moisturizer scientifically-proven to build the skin’s barrier back up. If you are interested in learning how to use peptides in skin care, you can most likely add a peptide-containing product to your current routine to further optimize your skin health. There’s no need to worry about debating between incorporating peptides vs retinol into your routine - you can use them in tandem. But always note, that not all peptides are created equal and you should ensure that the peptides you apply topically have been well researched for their safety,a nd ideally their efficacy as well.
06
Do topical peptides pair well with other ingredients used in your skin care regimen?
You’ll be happy to hear that peptide products typically pair well with most other skin care products. Unlike other ingredients, peptides generally don’t strip the skin or neutralize other ingredients. Peptides tend to work excellently alongside other ingredients, like hyaluronic acids and vitamin C. Additionally, you may consider pairing harsh skin products, such as retinol, with the use of a peptide moisturizer scientifically-proven to build the skin’s barrier back up. If you are interested in learning how to use peptides in skin care, you can most likely add a peptide-containing product to your current routine to further optimize your skin health. There’s no need to worry about debating between incorporating peptides vs retinol into your routine - you can use them in tandem. But always note, that not all peptides are created equal and you should ensure that the peptides you apply topically have been well researched for their safety,a nd ideally their efficacy as well.
07
What should you avoid using peptides with?
Peptides can be paired with almost any other porduct and ingredient. As a rule of thumb, theproduct that you apply first in your skin care regiment will absorb the best into your skin. Therefore, order your skin care routine based on the products/ingredients you want the most benefit from. On this note, you likely won't receive much benefit from a peptide if you apply a mineral sunscreen to your skin first. That's because mineral sunscreens form a physical barrier on skin and don't allow much penetration.
07
What should you avoid using peptides with?
Peptides can be paired with almost any other porduct and ingredient. As a rule of thumb, theproduct that you apply first in your skin care regiment will absorb the best into your skin. Therefore, order your skin care routine based on the products/ingredients you want the most benefit from. On this note, you likely won't receive much benefit from a peptide if you apply a mineral sunscreen to your skin first. That's because mineral sunscreens form a physical barrier on skin and don't allow much penetration.
08
How can you determine which peptide product is best?
There are so many peptide products on the market these days that it’s hard to know which ones actually work. When searching for the right peptide product, pay attention to the product’s scientific credibility and ensure there are validated studies to support the peptide’s safety and efficacy.Penetration studies, in particular, are key studies that should be conducted on products containing peptides. These studies offer an evidence-based look at how well a topical ingredient will penetrate through the skin’s layers, ultimately determining how effective a peptide can be when applied topically. [7]OneSkin is one of a select few companies that use penetration studies to ensure product efficacy. We have performed extensive research in the lab on human skin samples to confirm the ability of our proprietary peptide, OS-01, to penetrate down to the dermal layer of skin. Additionally, our scientists have developed a body of data supporting OS-01’s ability to improve collagen and hyaluronic acid biomarkers, increase the skin’s epidermal thickness, and improve skin’s barrier function. [8] The OS-01 peptide is ideal for topical application due to its superior penetration capabilities and its positive and proven impacts on healthy skin function.
08
How can you determine which peptide product is best?
There are so many peptide products on the market these days that it’s hard to know which ones actually work. When searching for the right peptide product, pay attention to the product’s scientific credibility and ensure there are validated studies to support the peptide’s safety and efficacy.Penetration studies, in particular, are key studies that should be conducted on products containing peptides. These studies offer an evidence-based look at how well a topical ingredient will penetrate through the skin’s layers, ultimately determining how effective a peptide can be when applied topically. [7]OneSkin is one of a select few companies that use penetration studies to ensure product efficacy. We have performed extensive research in the lab on human skin samples to confirm the ability of our proprietary peptide, OS-01, to penetrate down to the dermal layer of skin. Additionally, our scientists have developed a body of data supporting OS-01’s ability to improve collagen and hyaluronic acid biomarkers, increase the skin’s epidermal thickness, and improve skin’s barrier function. [8] The OS-01 peptide is ideal for topical application due to its superior penetration capabilities and its positive and proven impacts on healthy skin function.
Key Takeaways:
- Peptides are short chains of amino acids ( the “building blocks” of the proteins in your body) connected together from end to end.
- A peptide’s small size enables it to penetrate deep into skin tissues, effecting change that can lead to an improved skin barrier, skin damage repair, improved skin texture, and improved skin elasticity.
- Oral peptides can be obtained either through your diet or through oral peptide supplements. However, oral peptides, including collagen, are easily broken down by digestive acids and not delivered locally, therefore topical peptide-containing supplements offer a superior delivery method for skin health improvements.
- Not all peptide-products are made equal. Before using a peptide-containing product, it’s important to confirm the peptide’s scientific credibility and penetration capabilities.
- OneSkin’s line of Topical Supplements have been scientifically tested and validated, including through extensive penetration studies, confirming the OS-01 peptide’s ability to reach the dermal layer of skin.
Key Takeaways:
- Peptides are short chains of amino acids ( the “building blocks” of the proteins in your body) connected together from end to end.
- A peptide’s small size enables it to penetrate deep into skin tissues, effecting change that can lead to an improved skin barrier, skin damage repair, improved skin texture, and improved skin elasticity.
- Oral peptides can be obtained either through your diet or through oral peptide supplements. However, oral peptides, including collagen, are easily broken down by digestive acids and not delivered locally, therefore topical peptide-containing supplements offer a superior delivery method for skin health improvements.
- Not all peptide-products are made equal. Before using a peptide-containing product, it’s important to confirm the peptide’s scientific credibility and penetration capabilities.
- OneSkin’s line of Topical Supplements have been scientifically tested and validated, including through extensive penetration studies, confirming the OS-01 peptide’s ability to reach the dermal layer of skin.
References
- https://www.dermatologytimes.com/view/what-are-cosmeceutical-peptides
- https://www.medicalnewstoday.com/articles/326701#summary
- https://pubmed.ncbi.nlm.nih.gov/26362110/
- https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190134
- https://www.nature.com/articles/s41598-017-18454-z.pdf?origin=ppub
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583892/#R62
- https://onlinelibrary.wiley.com/doi/full/10.1111/srt.12968
- https://www.nature.com/articles/s41514-023-00109-1
References
- https://www.dermatologytimes.com/view/what-are-cosmeceutical-peptides
- https://www.medicalnewstoday.com/articles/326701#summary
- https://pubmed.ncbi.nlm.nih.gov/26362110/
- https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190134
- https://www.nature.com/articles/s41598-017-18454-z.pdf?origin=ppub
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583892/#R62
- https://onlinelibrary.wiley.com/doi/full/10.1111/srt.12968
- https://www.nature.com/articles/s41514-023-00109-1
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging