Skin Care is Health Care: Why Skin Care is the Key to Longevity
6 min read
September 29,2024
LONGEVITY
Skin Care is Health Care: Why Skin Care is the Key to Longevity
6 min read
September 29,2024
LONGEVITY
While your skin is a canvas for many cosmetic pursuits, it’s not just there for looks. As the body's largest organ, it stands as your first line of defense against the outside world.When asked what you want from your skin care, you might say fewer wrinkles, smoother texture, and a radiant tone. Yet, the skincare industry has often neglected a crucial truth: your skin is a vital organ, central to your overall health and longevity, akin to the heart, brain, and liver.Skin care should not be limited to enhancing appearance. It should optimize your skin’s biology to fortify your entire body against the aging process. OneSkin’s products transcend skin care as longevity-focused topical supplements.
While your skin is a canvas for many cosmetic pursuits, it’s not just there for looks. As the body's largest organ, it stands as your first line of defense against the outside world.When asked what you want from your skin care, you might say fewer wrinkles, smoother texture, and a radiant tone. Yet, the skincare industry has often neglected a crucial truth: your skin is a vital organ, central to your overall health and longevity, akin to the heart, brain, and liver.Skin care should not be limited to enhancing appearance. It should optimize your skin’s biology to fortify your entire body against the aging process. OneSkin’s products transcend skin care as longevity-focused topical supplements.
01
The Science Behind Skin Aging
Aging is a complex process affecting every cell, organ, and system in your body; your skin is no exception. With two square meters in size and over fifteen percent of your body weight, your skin is constantly exposed to internal and external factors that contribute to skin aging.[1]
Intrinsic Skin Aging
Intrinsic aging is the natural aging process that occurs over time, where bodily processes begin to slow and break down. Some intrinsic sources of skin aging include:
- Genetic Predisposition: Your genes significantly affect how your skin ages, accounting for up to 60% of variations in skin aging. Some people may naturally have more resilient skin, while others may be more prone to wrinkles and sagging.[2]
- Cellular Senescence: As you age, your cells gradually lose their ability to divide and function properly. This process, known as cellular senescence, leads to the accumulation of ‘zombie’ cells in your skin that secrete inflammatory compounds which contribute to wrinkles and loss of elasticity.[3]
- Decreased Collagen Production: Collagen is a protein that provides structure and support to your skin. Due to various factors like hormonal changes and the accumulation of senescent cells, your body produces less collagen as you age, leading to thinner, less resilient skin.[4]
01
The Science Behind Skin Aging
Aging is a complex process affecting every cell, organ, and system in your body; your skin is no exception. With two square meters in size and over fifteen percent of your body weight, your skin is constantly exposed to internal and external factors that contribute to skin aging.[1]
Intrinsic Skin Aging
Intrinsic aging is the natural aging process that occurs over time, where bodily processes begin to slow and break down. Some intrinsic sources of skin aging include:
- Genetic Predisposition: Your genes significantly affect how your skin ages, accounting for up to 60% of variations in skin aging. Some people may naturally have more resilient skin, while others may be more prone to wrinkles and sagging.[2]
- Cellular Senescence: As you age, your cells gradually lose their ability to divide and function properly. This process, known as cellular senescence, leads to the accumulation of ‘zombie’ cells in your skin that secrete inflammatory compounds which contribute to wrinkles and loss of elasticity.[3]
- Decreased Collagen Production: Collagen is a protein that provides structure and support to your skin. Due to various factors like hormonal changes and the accumulation of senescent cells, your body produces less collagen as you age, leading to thinner, less resilient skin.[4]
Extrinsic Skin Aging
Extrinsic aging, on the other hand, is influenced by external factors and lifestyle choices. Some of the most prominent sources of extrinsic skin aging include:
- Sun Exposure: Ultraviolet (UV) radiation from the sun is one of the primary causes of extrinsic aging. Characterized by wrinkles, sunspots, and an increased risk of skin cancer, up to 80% of the visible signs of aging can be attributed to UV exposure.[5] At the same time, even visible blue light can create oxidative stress in the skin by producing ROS, accelerating the aging process.[6]
- Pollution: Environmental pollutants can penetrate your skin, causing oxidative stress, which leads to inflammation and accelerating aging.[7]
- Lifestyle Factors: Smoking, poor diet, and lack of sleep can all contribute to premature skin aging. These factors increase oxidative stress and inflammation, which damage your skin over time.[8]
Extrinsic Skin Aging
Extrinsic aging, on the other hand, is influenced by external factors and lifestyle choices. Some of the most prominent sources of extrinsic skin aging include:
- Sun Exposure: Ultraviolet (UV) radiation from the sun is one of the primary causes of extrinsic aging. Characterized by wrinkles, sunspots, and an increased risk of skin cancer, up to 80% of the visible signs of aging can be attributed to UV exposure.[5] At the same time, even visible blue light can create oxidative stress in the skin by producing ROS, accelerating the aging process.[6]
- Pollution: Environmental pollutants can penetrate your skin, causing oxidative stress, which leads to inflammation and accelerating aging.[7]
- Lifestyle Factors: Smoking, poor diet, and lack of sleep can all contribute to premature skin aging. These factors increase oxidative stress and inflammation, which damage your skin over time.[8]
02
How Skin Aging Impacts Longevity
For years, scientists have known that skin strength deteriorates as we age, leaving the body more susceptible to infections that can have adverse health effects system-wide. However, new research suggests that skin aging may also be a silent trigger of systemic inflammation with age, termed “inflammaging,” revealing that skin care may be the missing link in extending human longevity.[9]
Inflammaging: A Root Cause of Aging
Systemic inflammation, one of the 12 hallmarks of aging, is the chronic, low-grade inflammation that becomes more prevalent as you age. This persistent state of inflammation is not an acute response to injury or infection but rather a continuous, systemic condition that quietly wreaks havoc on your body over time. Unlike short-term inflammation that helps you heal from wounds or fight off infections, inflammaging is a subtle and insidious process driven by factors like cellular senescence. Because the skin is directly vulnerable to intrinsic and extrinsic aging factors like oxidative stress, sun damage, and UV exposure, there is a strong link between skin health and inflammaging, an age-related and continuous state of body-wide inflammation. [10]The root of this link begins when your skin tries to repair age-related damage. In an attempt to restore hydration and mend vulnerabilities in its barrier function, aging skin increases the production of inflammatory molecules known as cytokines. As cytokine levels increase, they begin to accumulate in the blood, resulting in a body-wide state of inflammation that has direct connections to chronic conditions like Alzheimer’s disease, cancer, and heart disease.[10]
02
How Skin Aging Impacts Longevity
For years, scientists have known that skin strength deteriorates as we age, leaving the body more susceptible to infections that can have adverse health effects system-wide. However, new research suggests that skin aging may also be a silent trigger of systemic inflammation with age, termed “inflammaging,” revealing that skin care may be the missing link in extending human longevity.[9]
Inflammaging: A Root Cause of Aging
Systemic inflammation, one of the 12 hallmarks of aging, is the chronic, low-grade inflammation that becomes more prevalent as you age. This persistent state of inflammation is not an acute response to injury or infection but rather a continuous, systemic condition that quietly wreaks havoc on your body over time. Unlike short-term inflammation that helps you heal from wounds or fight off infections, inflammaging is a subtle and insidious process driven by factors like cellular senescence. Because the skin is directly vulnerable to intrinsic and extrinsic aging factors like oxidative stress, sun damage, and UV exposure, there is a strong link between skin health and inflammaging, an age-related and continuous state of body-wide inflammation. [10]The root of this link begins when your skin tries to repair age-related damage. In an attempt to restore hydration and mend vulnerabilities in its barrier function, aging skin increases the production of inflammatory molecules known as cytokines. As cytokine levels increase, they begin to accumulate in the blood, resulting in a body-wide state of inflammation that has direct connections to chronic conditions like Alzheimer’s disease, cancer, and heart disease.[10]
03
Shifting Skin Care from Symptoms to Root Causes
When it comes to skin care, treating the symptoms of aging rather than the causes of aging has long been the norm. Just look at the Botox industry, which has reached a whopping $3.5 billion annually. Consider for a moment what Botox is treating: wrinkles are just the surface symptoms of an underlying decline in skin health.Just as you wouldn't treat an aged heart with injectable plumper to make it appear healthier, the goal of skin care shouldn't be to just treat the appearance of mature skin and wish for it to be more youthful. Instead, your skin care needs to prioritize skin health first so that you can experience better-looking, stronger, and healthier skin as a result.
The Subjectivity Problem in Skincare Claims
The skincare industry has traditionally relied on subjective metrics to validate the effectiveness of its products. Before-and-after photos, customer surveys, and self-reported outcomes are commonly used to support clinical claims. While these methods can provide some insights, they lack the rigorous objectivity required to definitively prove a product's efficacy. OneSkin is changing that.
03
Shifting Skin Care from Symptoms to Root Causes
When it comes to skin care, treating the symptoms of aging rather than the causes of aging has long been the norm. Just look at the Botox industry, which has reached a whopping $3.5 billion annually. Consider for a moment what Botox is treating: wrinkles are just the surface symptoms of an underlying decline in skin health.Just as you wouldn't treat an aged heart with injectable plumper to make it appear healthier, the goal of skin care shouldn't be to just treat the appearance of mature skin and wish for it to be more youthful. Instead, your skin care needs to prioritize skin health first so that you can experience better-looking, stronger, and healthier skin as a result.
The Subjectivity Problem in Skincare Claims
The skincare industry has traditionally relied on subjective metrics to validate the effectiveness of its products. Before-and-after photos, customer surveys, and self-reported outcomes are commonly used to support clinical claims. While these methods can provide some insights, they lack the rigorous objectivity required to definitively prove a product's efficacy. OneSkin is changing that.
MolClock: The First Objective Skin-Specific Biological Clock
MolClock is the first-ever skin-specific biological clock designed to predict the skin's biological age based on epigenetic changes to the skin.[11] Unlike traditional methods that rely on subjective metrics, MolClock provides an objective, numerical assessment of skin health and aging. This innovation allows OneSkin to conclude definitively that our products are effective in a way others cannot.
MolClock: The First Objective Skin-Specific Biological Clock
MolClock is the first-ever skin-specific biological clock designed to predict the skin's biological age based on epigenetic changes to the skin.[11] Unlike traditional methods that rely on subjective metrics, MolClock provides an objective, numerical assessment of skin health and aging. This innovation allows OneSkin to conclude definitively that our products are effective in a way others cannot.
OS-01: The First Ingredient Scientifically Proven to Reverse Skin’s Biological Age
This is where OneSkin's revolutionary approach to skin care comes into play. Powered by our OS-01 peptide, which has been clinically validated to decrease key biomarkers of skin aging, increase epidermal thickness, and improve barrier function, our formulations tackle the root causes of skin aging to fortify your largest organ. [12,13] In fact, OS-01 FACE, OS-01 EYE, and OS-01 BODY are all clinically proven to improve barrier function, a key indicator of skin health.[12, 14]
OS-01: The First Ingredient Scientifically Proven to Reverse Skin’s Biological Age
This is where OneSkin's revolutionary approach to skin care comes into play. Powered by our OS-01 peptide, which has been clinically validated to decrease key biomarkers of skin aging, increase epidermal thickness, and improve barrier function, our formulations tackle the root causes of skin aging to fortify your largest organ. [12,13] In fact, OS-01 FACE, OS-01 EYE, and OS-01 BODY are all clinically proven to improve barrier function, a key indicator of skin health.[12, 14]
Pausing Inflammaging With OS-01 BODY
Based on these results, we hypothesized that delivering the benefits of OS-01 across the body could enhance overall bodily longevity. To test this, we conducted a 12-week clinical study involving 52 participants using OS-01 BODY or a control formulation (a standard drugstore moisturizer). Blood samples were collected at baseline and after 12 weeks to measure circulating cytokine levels, and the biological age was assessed using GlycanAge. The results were compelling: IL-8 levels significantly decreased in participants using OS-01 BODY, and their biological age remained unchanged. In contrast, those using the control formulation experienced an increase in biological age. This suggests that treating body skin with OS-01 BODY, powered by the OS-01 peptide, effectively reduced circulating inflammation and helped pause overall biological aging.[12]
Pausing Inflammaging With OS-01 BODY
Based on these results, we hypothesized that delivering the benefits of OS-01 across the body could enhance overall bodily longevity. To test this, we conducted a 12-week clinical study involving 52 participants using OS-01 BODY or a control formulation (a standard drugstore moisturizer). Blood samples were collected at baseline and after 12 weeks to measure circulating cytokine levels, and the biological age was assessed using GlycanAge. The results were compelling: IL-8 levels significantly decreased in participants using OS-01 BODY, and their biological age remained unchanged. In contrast, those using the control formulation experienced an increase in biological age. This suggests that treating body skin with OS-01 BODY, powered by the OS-01 peptide, effectively reduced circulating inflammation and helped pause overall biological aging.[12]
Related Products
Related Products
Key Takeaways:
- As the body’s largest organ, It's essential to recognize the skin’s critical role in overall health and longevity, not just its cosmetic value.
- Skin aging is influenced by various Intrinsic and extrinsic factors that significantly contribute to systemic inflammation or "inflammaging," a chronic, low-grade inflammation that accelerates the entire body’s aging process.
- Traditional skincare has focused on treating the symptoms of aging, like wrinkles, rather than addressing the underlying causes.
- Effective skin care should optimize a shift towards enhancing skin health at the cellular level, which can lead to better overall health outcomes and even extend longevity, along with improving skin’s appearance.
Key Takeaways:
- As the body’s largest organ, It's essential to recognize the skin’s critical role in overall health and longevity, not just its cosmetic value.
- Skin aging is influenced by various Intrinsic and extrinsic factors that significantly contribute to systemic inflammation or "inflammaging," a chronic, low-grade inflammation that accelerates the entire body’s aging process.
- Traditional skincare has focused on treating the symptoms of aging, like wrinkles, rather than addressing the underlying causes.
- Effective skin care should optimize a shift towards enhancing skin health at the cellular level, which can lead to better overall health outcomes and even extend longevity, along with improving skin’s appearance.
Disclaimers
- This article was initially published in April 2022 and has been updated.
Disclaimers
- This article was initially published in April 2022 and has been updated.
References
- https://www.ncbi.nlm.nih.gov/books/NBK279255/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085290/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524668/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824545/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344124/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307003/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320051/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586245/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669244/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248351/
- Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020.
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.
References
- https://www.ncbi.nlm.nih.gov/books/NBK279255/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085290/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8524668/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824545/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344124/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307003/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320051/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8586245/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10669244/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248351/
- Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020.
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age and senescence burden in human skin models. Npj Aging, 9(1), 1-15. 2023.
- Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Discover More
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
Discover More
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging