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OS-01 BODY MOISTURIZER

250 mL / 8.45 fl oz

OS-01 BODY MOISTURIZER

Topical Supplement

250 mL / 8.45 fl oz

Revive thin, crepey skin with our daily body moisturizer, powered by the OS-01 PeptideTM and OneSkin Longevity ScienceTM.01



  • Improves skin texture, appearance, and hydration

  • Strengthens the skin barrier by up to +41%

  • Dermatologist tested, fragrance-free, safe for sensitive skin

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OS-01 FACE, Travel Size

Travel-size OS-01 FACE with your first subscription

$42 FREE

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  • Certified Plastic Neutral logo on a white background
  • Leaping bunny certified logo
  • Accepted National Eczema Association logo

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BENEFITS

Nourishing body moisturizer and targeted treatment for thin, crepey skin

Smooth texture

Improves the root cause of crepey skin by supporting epidermal thickness for a firmer look and feel.01

Deep hydration

Replenishes and locks in hydration to keep skin soft, plump, and nourished.01

Barrier support

Fortifies the skin barrier to protect against daily stressors and moisture loss.01

5-STAR REVIEWS

See why customers love OS-01 BODY

“The skin on my legs was starting to look older, dry and crepey at 46. Now it is plump and youthful like it was 10 years ago after only a few weeks.” – Jen A.

"The One skin, OS-O1 Body, has been a game changer, within a few weeks I saw a remarkable difference in the quality of my skin, and my skin's appearance continues to improve with daily application. It now has a tighter, less dry look and the texture has almost returned to my premenopause condition..more moist and fresh in appearance. Science is everything, and One Skin has got the science spot on." – Tia T.


"I love this body lotion. My crepey skin is transforming. I wish I had taken pictures before I started using it but I have tried so many different products with no results that I didn’t have much confidence that this one would be any different. Boy was I wrong. I’m hoping that it will eventually get rid of all my dark spots on my skin. I will be a forever customer..."– Myra P.

CLINICAL DATA

Visible results, scientifically validated

93
of participants reported improved hydration 01

72
of participants reported improved appearance 01

70
of participants reported improved texture 01

41
Improvement in skin barrier function was measured 01

Getting started with OS-01 BODY

Follow these easy steps for optimal results

  • Apply to arms, legs, chest, back, and stomach
  • Massage until absorbed
  • Use 2 times daily

How it works

Powered by the OS-01 Senescence Blocking Peptide™

The first and only peptide scientifically proven to reverse skin’s biological age.02,03

All Ingredients

Water, Glycerin, Limnanthes Alba (Meadowfoam) Seed Oil, Sorbitan Olivate, Avena Sativa (Oat) Kernel Oil, Squalane, Prunus Domestica Seed Oil, Saccharide Isomerate, Cetearyl Olivate, d-Panthenol, Mangifera Indica (Mango) Seed Butter, Tremella Fuciformis (Mushroom) Extract, Tocopheryl acetate, Decapeptide-52*, Allantoin, Asiaticoside, Centella Asiatica Extract, Sodium Hyaluronate Crosspolymer, Ceramide NP, Anadenanthera Colubrina Bark Extract, Lepidium Sativum Sprout Extract, Genistein, Niacinamide, Glycerol, Bentonite, Cetyl Palmitate, Sorbitan Palmitate, Lecithin, Xanthan Gum, Polyglyceryl-10 Laurate, Polyglyceryl-6 Oleate, Sorbitan Oleate, Glyceryl Caprylate, Polysorbate 80, Alcohol, Caprylyl Glycol, Sorbic Acid, Citric Acid, Sodium Citrate, Pentylene Glycol, Potassium Sorbate, Ethylhexylglycerin, Caprylhydroxamic Acid, Tetrasodium Glutamate Diacetate, Phenoxyethanol. *OS-01 Peptide

Citations

01Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims

02Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age   and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1

03Boroni, M. et al. Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging. Clinical Epigenetics 12, 105. 2020. doi:10.1186/s13148-020-00899-1

OS-01 BODY MOISTURIZER

4.7
Rated 4.7 out of 5 stars
Based on 3,337 reviews
Total 5 star reviews: 2.6k Total 4 star reviews: 423 Total 3 star reviews: 169 Total 2 star reviews: 53 Total 1 star reviews: 46
92%would recommend these products
3,337 reviews
  • D
    Dianne
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    24 minutes ago
    5 Stars

    Best eye cream ever!!

  • RA
    Raelyn A.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    8 hours ago
    Amazing!

    This is the best lotion I have used!

  • CR
    Cyndi R.
    Verified Buyer
    Reviewing
    OS-01 BODY
    I recommend this product
    Rated 5 out of 5 stars
    18 hours ago
    Dry skin to soft.

    I’m 66 and the skin on my arms and legs has been extremely dry for several years now. Sun damage most likely plays a part in that. I’ve tried so many lotions as well as castor oil and tallow balm. Consistent use of Oneskin has made my skin soft again. It feels so nice to touch now!

  • KA
    Kathy A.
    Verified Buyer
    Reviewing
    OS-01 BODY MOISTURIZER
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Love the feel!

    I have used so many body lotions and this one just feels so great on my skin. I haven’t used it long enough to see a difference, but I’m enjoying the process along the way.

  • JC
    Joan C.
    Verified Buyer
    Reviewing
    OS-01 BODY
    Rated 3 out of 5 stars
    Yesterday
    OK

    After several months of use I see a very modest improvement in skin.

    OneSkin
    4 minutes ago

    Hi Joan! Thank you so much for your thoughtful feedback about OS-01 BODY MOISTURIZER — and for giving it several months of consistent use before sharing your experience. That kind of commitment truly helps us understand how our formula works across different skin types, and we're genuinely glad you're seeing some positive changes!

    We hear you that you were hoping for more noticeable results, and we want to make sure you're set up for the best outcome possible. Here are a few tips that can help amplify what you're already seeing:

    • Apply to damp skin immediately after showering to maximize absorption — this can make a real difference in how deeply the formula penetrates.
    • Use twice daily (morning and night) if you haven't already, as consistent layering tends to accelerate visible improvement.
    • Make sure you're using a generous amount — the skin on the body needs more product than most people expect.

    Every person's skin responds on its own timeline, and we believe with a few adjustments you may start to see more of the results you're looking for. We'd love to hear how things progress — and if you ever want personalized guidance, our team is always happy to help!

    Thank you again for taking the time to share your honest experience, Joan. Your feedback truly means the world to all of us at OneSkin! 🤍