How OS-01 Can Help Your Collagen Levels As You Age
7 min read
May 31,2023
ONESKIN PRODUCTS
How OS-01 Can Help Your Collagen Levels As You Age
7 min read
May 31,2023
ONESKIN PRODUCTS
From smoothie powders to anti-aging creams, collagen seems to be everywhere these days. So what is collagen and why is it so important to our skin health? Join us as we take a closer look at collagen and what we can do to maintain healthy levels of this protein within our skin as we age.
From smoothie powders to anti-aging creams, collagen seems to be everywhere these days. So what is collagen and why is it so important to our skin health? Join us as we take a closer look at collagen and what we can do to maintain healthy levels of this protein within our skin as we age.
01
What is collagen?
The most abundant protein in the body, collagen is one of the main structural proteins that gives healthy skin its firmness and volume. Throughout our lives, our skin is constantly creating new collagen to help repair damage and replenish levels. This regeneration is thanks mostly to fibroblasts, cells that specialize in the creation of collagen and other connective tissues. ¹As we age, collagen naturally decreases by about 1-1.5% per year. ² This decline can be especially pronounced in women, who lose on average 30% of their skin’s collagen in the five years after menopause. ³ With less collagen formation to keep it plump and firm, the skin begins to show telltale signs of aging like fine lines, deeper wrinkles, and poor skin elasticity.
01
What is collagen?
The most abundant protein in the body, collagen is one of the main structural proteins that gives healthy skin its firmness and volume. Throughout our lives, our skin is constantly creating new collagen to help repair damage and replenish levels. This regeneration is thanks mostly to fibroblasts, cells that specialize in the creation of collagen and other connective tissues. ¹As we age, collagen naturally decreases by about 1-1.5% per year. ² This decline can be especially pronounced in women, who lose on average 30% of their skin’s collagen in the five years after menopause. ³ With less collagen formation to keep it plump and firm, the skin begins to show telltale signs of aging like fine lines, deeper wrinkles, and poor skin elasticity.
02
Why do collagen levels by age decrease?
Like much of skin aging, collagen degradation, often called collagen breakdown, is caused by a confluence of both extrinsic and intrinsic aging factors. Sun exposure, which is responsible for up to 80% of extrinsic aging, leads to the rapid development of collagen-degrading enzymes called matrix metalloproteinases (MMPs). Intrinsic aging factors triggered by our genetics also gradually increase MMPs as we age, leading to even more collagen degradation yearly. While the destruction of existing collagen by MMPs is central to the aging process, the skin’s failure to replace damaged collagen with fresh protein is also a major contributor to collagen decline. In recent studies, researchers found that the presence of damaged collagen in severely photodamaged skin inhibits the creation of new collagen. This is partly due to the fact that damaged collagen does not support the mechanical tension that’s necessary for fibroblasts to efficiently create new collagen. Plus, as fibroblasts themselves experience aging, they become less efficient at creating new collagen. This is due to cellular senescence, the accumulation of aged zombie cells that induce aging in neighboring cells. All types of cells are vulnerable to senescence–even collagen-synthesizing fibroblasts. As more and more fibroblasts fall into senescence, the skin can no longer maintain robust collagen production.So how much does collagen really decrease over time? Researchers have found that collagen production in people over 80 is just 25% of what it is in young adults. Of the 75% decrease, 45% is attributed to fibroblast senescence and the remaining 30% to other factors including reduced mechanical tension. ⁴
02
Why do collagen levels by age decrease?
Like much of skin aging, collagen degradation, often called collagen breakdown, is caused by a confluence of both extrinsic and intrinsic aging factors. Sun exposure, which is responsible for up to 80% of extrinsic aging, leads to the rapid development of collagen-degrading enzymes called matrix metalloproteinases (MMPs). Intrinsic aging factors triggered by our genetics also gradually increase MMPs as we age, leading to even more collagen degradation yearly. While the destruction of existing collagen by MMPs is central to the aging process, the skin’s failure to replace damaged collagen with fresh protein is also a major contributor to collagen decline. In recent studies, researchers found that the presence of damaged collagen in severely photodamaged skin inhibits the creation of new collagen. This is partly due to the fact that damaged collagen does not support the mechanical tension that’s necessary for fibroblasts to efficiently create new collagen. Plus, as fibroblasts themselves experience aging, they become less efficient at creating new collagen. This is due to cellular senescence, the accumulation of aged zombie cells that induce aging in neighboring cells. All types of cells are vulnerable to senescence–even collagen-synthesizing fibroblasts. As more and more fibroblasts fall into senescence, the skin can no longer maintain robust collagen production.So how much does collagen really decrease over time? Researchers have found that collagen production in people over 80 is just 25% of what it is in young adults. Of the 75% decrease, 45% is attributed to fibroblast senescence and the remaining 30% to other factors including reduced mechanical tension. ⁴
03
Maintain healthy collagen levels with OS-01
Preserving collagen production as we age keeps our skin stronger with every passing year. That’s why we developed OS-01
, the first peptide that has been shown to reduce the accumulation of senescent fibroblasts by up to 50% in the skin.* 5 By preventing fibroblasts from falling into senescence, OS-01 helps maintain the cellular engines that keep the skin supplied with fresh, new collagen.
03
Maintain healthy collagen levels with OS-01
Preserving collagen production as we age keeps our skin stronger with every passing year. That’s why we developed OS-01
, the first peptide that has been shown to reduce the accumulation of senescent fibroblasts by up to 50% in the skin.* 5 By preventing fibroblasts from falling into senescence, OS-01 helps maintain the cellular engines that keep the skin supplied with fresh, new collagen.
04
How does OS-01 prevent collagen loss?
We know OS-01 keeps our fibroblasts healthy so they can create new collagen. But can it also prevent collagen degradation in the first place? To find out if OS-01 shields against the collagen-degrading effects of UV radiation, our scientists exposed in vitro
human dermal fibroblasts to UVB radiation and then immediately treated them with the OS-01 peptide. As expected, cells exposed to UVB radiation alone expressed significantly higher levels of collagen-degrading MMP3. However, cells immediately treated with the OS-01 peptide after exposure did not experience a significant increase in MMP3, indicating that the OS-01 peptide can prevent UVB-induced MMP3 expression.* 5 This means that the OS-01 peptide may help prevent degradation induced by photodamage, a leading extrinsic cause of collagen loss.
04
How does OS-01 prevent collagen loss?
We know OS-01 keeps our fibroblasts healthy so they can create new collagen. But can it also prevent collagen degradation in the first place? To find out if OS-01 shields against the collagen-degrading effects of UV radiation, our scientists exposed in vitro
human dermal fibroblasts to UVB radiation and then immediately treated them with the OS-01 peptide. As expected, cells exposed to UVB radiation alone expressed significantly higher levels of collagen-degrading MMP3. However, cells immediately treated with the OS-01 peptide after exposure did not experience a significant increase in MMP3, indicating that the OS-01 peptide can prevent UVB-induced MMP3 expression.* 5 This means that the OS-01 peptide may help prevent degradation induced by photodamage, a leading extrinsic cause of collagen loss.
Expression analysis of human dermal fibroblasts without treatment, exposed to 0.1 J/cm2 UVB and exposed to UVB followed by treatment with 12.5 μM OS-01 peptide. Data was normalized to the expression of untreated human dermal fibroblasts not exposed to UVB. Data representative of ≥3 independent experiments in triplicate. (*p<0.05) (Zonari, et al., npj Aging, 2023)
Expression analysis of human dermal fibroblasts without treatment, exposed to 0.1 J/cm2 UVB and exposed to UVB followed by treatment with 12.5 μM OS-01 peptide. Data was normalized to the expression of untreated human dermal fibroblasts not exposed to UVB. Data representative of ≥3 independent experiments in triplicate. (*p<0.05) (Zonari, et al., npj Aging, 2023)
05
How does OS-01 support collagen production?
To further validate the impact of OS-01 on collagen production, our team analyzed whether the peptide’s effects correlated to an increase in a key collagen production marker. The data provided a clear result. In a lab study examining the dermis of ex vivo
human skin samples, the OS-01 peptide was shown to increase a key marker associated with collagen production, COL1A1. It also increased a key marker associated with cell proliferation, MKI67.* 5 This data indicates that OS-01 can support the creation of more collagen-producing cells, which likely contributes to an overall increase in collagen production.
05
How does OS-01 support collagen production?
To further validate the impact of OS-01 on collagen production, our team analyzed whether the peptide’s effects correlated to an increase in a key collagen production marker. The data provided a clear result. In a lab study examining the dermis of ex vivo
human skin samples, the OS-01 peptide was shown to increase a key marker associated with collagen production, COL1A1. It also increased a key marker associated with cell proliferation, MKI67.* 5 This data indicates that OS-01 can support the creation of more collagen-producing cells, which likely contributes to an overall increase in collagen production.
Expression analysis of ex vivo human skin samples (35, 55, and 79 yr) exposed to the OS-01 peptide (12.5uM) over 5 days, analyzed in the dermis. (Zonari, et al., npj Aging, 2023).
Expression analysis of ex vivo human skin samples (35, 55, and 79 yr) exposed to the OS-01 peptide (12.5uM) over 5 days, analyzed in the dermis. (Zonari, et al., npj Aging, 2023).
06
Do OneSkin Topical Supplements support collagen?
To ensure that our Topical Supplements provide the collagen-boosting effects of OS-01, we tested the expression of the same marker, COL1A1 and MKi67, on ex vivo skin samples exposed to OS-01 FACE
and found that topical treatment with OS-01 FACE significantly increased COL1A1 and MKi67.* 5
06
Do OneSkin Topical Supplements support collagen?
To ensure that our Topical Supplements provide the collagen-boosting effects of OS-01, we tested the expression of the same marker, COL1A1 and MKi67, on ex vivo skin samples exposed to OS-01 FACE
and found that topical treatment with OS-01 FACE significantly increased COL1A1 and MKi67.* 5
Shown in lab studies on human skin samples by measuring key collagen production biomarker, COL1A1, and cellular proliferation biomarker, MKi67. Skin treated with OS-01 FACE displayed a significant increase compared to skin with no treatment. (Zonari, A., et al. npj Aging, 2023, supplementary information)
When formulating OS-01 EYE, we performed a similar lab study. We found that exposure to OS-01 EYE increased COL1A1 and decreased a key marker associated with collagen degradation, MMP1, in ex vivo human eyelid skin.*
Shown in lab studies on human skin samples by measuring key collagen production biomarker, COL1A1, and cellular proliferation biomarker, MKi67. Skin treated with OS-01 FACE displayed a significant increase compared to skin with no treatment. (Zonari, A., et al. npj Aging, 2023, supplementary information)
When formulating OS-01 EYE, we performed a similar lab study. We found that exposure to OS-01 EYE increased COL1A1 and decreased a key marker associated with collagen degradation, MMP1, in ex vivo human eyelid skin.*
Shown in lab studies on ex vivo human eyelid skin samples (42, 59, 84 yr) by measuring key collagen production biomarker, COL1A1, and key collagen degradation biomarker, MMP1. Skin treated with OS-01 EYE displayed a close to significant (p=0.11) increase in COL1A1 and a significant decrease in MMP1 (p=0.0445) compared to skin with no treatment.
Finally, we tested collagen levels in skin exposed to OS-01 FACE and OS-01 EYE, and found that collagen levels were increase by 140% with OS-01 FACE and 230% with OS-01 EYE. This can be explained by the fact that OS-01 EYE contains the highest concentration of the OS-01 peptide to target accelarated aging in this ultra-delicate area of skin.
Shown in lab studies on ex vivo human eyelid skin samples (42, 59, 84 yr) by measuring key collagen production biomarker, COL1A1, and key collagen degradation biomarker, MMP1. Skin treated with OS-01 EYE displayed a close to significant (p=0.11) increase in COL1A1 and a significant decrease in MMP1 (p=0.0445) compared to skin with no treatment.
Finally, we tested collagen levels in skin exposed to OS-01 FACE and OS-01 EYE, and found that collagen levels were increase by 140% with OS-01 FACE and 230% with OS-01 EYE. This can be explained by the fact that OS-01 EYE contains the highest concentration of the OS-01 peptide to target accelarated aging in this ultra-delicate area of skin.
Shown in lab studies on ex vivo human eyelid skin samples (70 yr) by analyzing levels of collagen in skin treated with OS-01 FACE and OS-01 EYE compared to no treatment. Skin treated with OS-01 FACE displayed an increase (not statistically significant) and skin treated with OS-01 EYE displayed a significant increase compared to skin with no treatment. Data was measured in triplicate.
This shows that OS-01 FACE and OS-01 EYE may help improve collagen biosynthesis and retention on the cellular level similar to the results observed with the OS-01 peptide alone – giving you an easy way to protect and maintain healthy collagen for years to come.*Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
Shown in lab studies on ex vivo human eyelid skin samples (70 yr) by analyzing levels of collagen in skin treated with OS-01 FACE and OS-01 EYE compared to no treatment. Skin treated with OS-01 FACE displayed an increase (not statistically significant) and skin treated with OS-01 EYE displayed a significant increase compared to skin with no treatment. Data was measured in triplicate.
This shows that OS-01 FACE and OS-01 EYE may help improve collagen biosynthesis and retention on the cellular level similar to the results observed with the OS-01 peptide alone – giving you an easy way to protect and maintain healthy collagen for years to come.*Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
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Key Takeaways:
- Collagen is one of the main structural proteins in the skin that gives it firmness and volume. As we age, collagen production decreases.
- Both extrinsic and intrinsic aging factors damage existing natural collagen and increase senescence, which makes it difficult for collagen-producing fibroblasts to replace damaged collagen.
- The OS-01 peptide has been shown to reduce the accumulation of senescent fibroblasts by up to 50% (Zonari, et al), helping to maintain the engines that keep the skin supplied with fresh new collagen.
- In lab studies, the OS-01 peptide has also been shown to help protect against UV-induced collagen degradation and increase key markers associated with collagen production (Zonari, et al).
- With the OS-01 peptide at the core of their formulas, both OS-01 FACE & OS-01 EYE have been shown to increase a key marker associated with collagen production in lab studies on human skin samples.
Key Takeaways:
- Collagen is one of the main structural proteins in the skin that gives it firmness and volume. As we age, collagen production decreases.
- Both extrinsic and intrinsic aging factors damage existing natural collagen and increase senescence, which makes it difficult for collagen-producing fibroblasts to replace damaged collagen.
- The OS-01 peptide has been shown to reduce the accumulation of senescent fibroblasts by up to 50% (Zonari, et al), helping to maintain the engines that keep the skin supplied with fresh new collagen.
- In lab studies, the OS-01 peptide has also been shown to help protect against UV-induced collagen degradation and increase key markers associated with collagen production (Zonari, et al).
- With the OS-01 peptide at the core of their formulas, both OS-01 FACE & OS-01 EYE have been shown to increase a key marker associated with collagen production in lab studies on human skin samples.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging