7 Keys to Understanding Menopause and Skin Changes
8 min read
OCT 30, 2023
May 20,2023
HEALTH
7 Keys to Understanding Menopause and Skin Changes
8 min read
OCT 30, 2023
May 20,2023
HEALTH
The female body has an incredible potential for transformation, including three major hormonal shifts that occur during a woman’s lifetime: puberty, pregnancy, and menopause. As our hormones change in the years leading up to menopause, so does our skin. Let’s take a closer look at the biological triggers behind these changes – and what you can do to keep your skin healthy and comfortable from perimenopause and beyond.
The female body has an incredible potential for transformation, including three major hormonal shifts that occur during a woman’s lifetime: puberty, pregnancy, and menopause. As our hormones change in the years leading up to menopause, so does our skin. Let’s take a closer look at the biological triggers behind these changes – and what you can do to keep your skin healthy and comfortable from perimenopause and beyond.
01
What happens during menopause?
Many of the menopausal symptoms that women experience during perimenopause and menopause are due to shifts in two key hormones: estrogen and progesterone. It all starts in the hypothalamus, an area in the brain that secretes hormones. The hypothalamus stimulates the anterior pituitary gland, which releases follicle-stimulating hormone (FSH) and luteinizing hormone (LH)1. FSH and LH kickstart ovarian production of estrogen and progesterone. In the years leading up to menopause, the ovaries start to lose their sensitivity to FSH and LH, yielding lower estrogen and progesterone levels2.
01
What happens during menopause?
Many of the menopausal symptoms that women experience during perimenopause and menopause are due to shifts in two key hormones: estrogen and progesterone. It all starts in the hypothalamus, an area in the brain that secretes hormones. The hypothalamus stimulates the anterior pituitary gland, which releases follicle-stimulating hormone (FSH) and luteinizing hormone (LH)1. FSH and LH kickstart ovarian production of estrogen and progesterone. In the years leading up to menopause, the ovaries start to lose their sensitivity to FSH and LH, yielding lower estrogen and progesterone levels2.
Estrogen Levels
Normal estrogen levels plummet from 30 - 400 pg/mL before menopause to 0 - 30 pg/mL after menopause.3 Because estrogen stimulates the production of several important proteins in the skin, this massive hormonal shift can weaken skin thickness over time.4 The impacts of declining estrogen are more than skin-deep; in fact, lower levels after menopause can impact several bodily systems, including:
Estrogen Levels
Normal estrogen levels plummet from 30 - 400 pg/mL before menopause to 0 - 30 pg/mL after menopause.3 Because estrogen stimulates the production of several important proteins in the skin, this massive hormonal shift can weaken skin thickness over time.4 The impacts of declining estrogen are more than skin-deep; in fact, lower levels after menopause can impact several bodily systems, including:
Progesterone Levels
Along with estrogen, progesterone levels also decrease during perimenopause. This critical hormone is known to lower the risk of anxiety and depression, regulate blood pressure, improve sleep, and promote uterine health. 8 Plus, because progesterone is involved in the skin’s oil production, declining progesterone levels may lead to increased skin dryness and sensitivity.
Progesterone Levels
Along with estrogen, progesterone levels also decrease during perimenopause. This critical hormone is known to lower the risk of anxiety and depression, regulate blood pressure, improve sleep, and promote uterine health. 8 Plus, because progesterone is involved in the skin’s oil production, declining progesterone levels may lead to increased skin dryness and sensitivity.
02
What happens to our skin during menopause?
Estrogen and progesterone interact with several crucial levers in skin health. During perimenopause, menopause, and post-menopause, the following factors can be affected.
02
What happens to our skin during menopause?
Estrogen and progesterone interact with several crucial levers in skin health. During perimenopause, menopause, and post-menopause, the following factors can be affected.
Collagen Production
Collagen is a structural protein that promotes skin strength, elasticity, and firmness.9 Fibroblasts, the skin cells that stimulate collagen production, are activated when exposed to estrogen. When estrogen levels drop, so does fibroblast activation and collagen production.9 Consequently, around 30% of skin collagen is lost within the first five years following menopause, leading to a weakened skin barrier and loss of firmness and elasticity.9
Collagen Production
Collagen is a structural protein that promotes skin strength, elasticity, and firmness.9 Fibroblasts, the skin cells that stimulate collagen production, are activated when exposed to estrogen. When estrogen levels drop, so does fibroblast activation and collagen production.9 Consequently, around 30% of skin collagen is lost within the first five years following menopause, leading to a weakened skin barrier and loss of firmness and elasticity.9
Oxidative Defenses
A primary cause of skin aging is exposure to free radicals, which oxidize cellular DNA. Oxidation-induced changes lead to genomic instability and epigenetic alterations - two of the twelve hallmarks of aging
.12 Although it’s not quite clear how, estrogen has been shown to have protective power against free radicals.13 As estrogen levels drop, this oxidative defense becomes less effective, and skin aging accelerates.
Oxidative Defenses
A primary cause of skin aging is exposure to free radicals, which oxidize cellular DNA. Oxidation-induced changes lead to genomic instability and epigenetic alterations - two of the twelve hallmarks of aging
.12 Although it’s not quite clear how, estrogen has been shown to have protective power against free radicals.13 As estrogen levels drop, this oxidative defense becomes less effective, and skin aging accelerates.
Sebum Production
Due to an age-related decline in cell turnover rate, skin oil glands– specifically sebaceous glands– become less effective. This is why many people notice their skin getting drier with time. Hormonal changes in menopause can exacerbate this decline, as sebaceous glands are affected by both estrogen and progesterone.14
Sebum Production
Due to an age-related decline in cell turnover rate, skin oil glands– specifically sebaceous glands– become less effective. This is why many people notice their skin getting drier with time. Hormonal changes in menopause can exacerbate this decline, as sebaceous glands are affected by both estrogen and progesterone.14
Hyaluronic Acid Production
Estrogen stimulates the production of hyaluronic acid, a substance known for its capacity to hold water and keep the skin hydrated. Without a strong skin barrier and estrogen-stimulated production of hyaluronic acid, the skin can become dehydrated.14
Hyaluronic Acid Production
Estrogen stimulates the production of hyaluronic acid, a substance known for its capacity to hold water and keep the skin hydrated. Without a strong skin barrier and estrogen-stimulated production of hyaluronic acid, the skin can become dehydrated.14
Melanin Production
Estrogen supports the synthesis of melanin, the pigment that helps protect skin from UV radiation. As estrogen declines, melanin levels lower, and skin becomes lighter and more sensitive to sun damage.15 Even though menopause reduces melanin production, erratic hormone levels and a weakened skin barrier can actually cause or worsen hyperpigmentation.
Wound Healing
When your skin is wounded, cytokines in the blood recruit inflammatory cells and nearby skin cells to start the healing process. Because estrogen regulates cytokine levels, wound healing may slow after menopause. In fact, topical estrogen has been shown to accelerate wound healing in both elderly men and women.14
Wound Healing
When your skin is wounded, cytokines in the blood recruit inflammatory cells and nearby skin cells to start the healing process. Because estrogen regulates cytokine levels, wound healing may slow after menopause. In fact, topical estrogen has been shown to accelerate wound healing in both elderly men and women.14
03
How can these skin problems be best avoided to extend the longevity of healthy skin?
Fortunately, it is possible to prepare our skin for menopause. Here are some lifestyle and skin care tips you can use to improve skin health, and extend skinspan:Anitoxidants: Eating foods rich in antioxidants or using topical skin care products with antioxidants can reduce oxidative stress and increase collagen levels! In general, topically applied antioxidants are more effective for skin health.Sunscreen: Post-menopausal skin is highly sensitive to sun damage. Wearing sunscreen can prevent accelerated skin aging and the development of age spots and skin cancer.Moisturize: Invest in a peptide moisturizer and hydrating cleanser. This can prevent skin dryness and keep your skin protected against environmental irritants. Consider Hormone Replacement Therapies (HRTs):
Consult your physician regarding your options for hormone therapy. Even topical estrogen effectively increases skin collagen and reduces skin age.16
Sleep: Sleeping at consistent times for around 7 - 9 hours daily can support hormone balance and skin health.17
03
How can these skin problems be best avoided to extend the longevity of healthy skin?
Fortunately, it is possible to prepare our skin for menopause. Here are some lifestyle and skin care tips you can use to improve skin health, and extend skinspan:Anitoxidants: Eating foods rich in antioxidants or using topical skin care products with antioxidants can reduce oxidative stress and increase collagen levels! In general, topically applied antioxidants are more effective for skin health.Sunscreen: Post-menopausal skin is highly sensitive to sun damage. Wearing sunscreen can prevent accelerated skin aging and the development of age spots and skin cancer.Moisturize: Invest in a peptide moisturizer and hydrating cleanser. This can prevent skin dryness and keep your skin protected against environmental irritants. Consider Hormone Replacement Therapies (HRTs):
Consult your physician regarding your options for hormone therapy. Even topical estrogen effectively increases skin collagen and reduces skin age.16
Sleep: Sleeping at consistent times for around 7 - 9 hours daily can support hormone balance and skin health.17
How does the OS-01 peptide address menopausal skin changes?
Our OS-01 peptide
is scientifically proven to counteract some of the factors caused by estrogen decline. In lab studies, OS-01 was shown to increase the activity of collagen and hyaluronic acid production genes (COL1A1 and HAS2).18 This shows that OS-01 may help to counteract decreasing levels of collagen and hyaluronic acid that occur after menopause–improving skin firmness, elasticity, strength, and hydration.19 OS-01 has also been shown to reduce
cellular senescence – the central hallmark of skin aging – and improve skin health at the cellular level.18
Our OS-01 FACE and OS-01 BODY Topical Supplements pair our star peptide with potent hydrating ingredients and antioxidants so your skin can stay supple and resilient even as its natural defenses decline. How does the OS-01 peptide address menopausal skin changes?
Our OS-01 peptide
is scientifically proven to counteract some of the factors caused by estrogen decline. In lab studies, OS-01 was shown to increase the activity of collagen and hyaluronic acid production genes (COL1A1 and HAS2).18 This shows that OS-01 may help to counteract decreasing levels of collagen and hyaluronic acid that occur after menopause–improving skin firmness, elasticity, strength, and hydration.19 OS-01 has also been shown to reduce
cellular senescence – the central hallmark of skin aging – and improve skin health at the cellular level.18
Our OS-01 FACE and OS-01 BODY Topical Supplements pair our star peptide with potent hydrating ingredients and antioxidants so your skin can stay supple and resilient even as its natural defenses decline. Shown in lab studies on human skin samples and/or cells by measuring key aging biomarker, CDKN2A, and key collagen and hyaluronic acid biomarkers, COL1A1 and HAS2. Treatment with the OS-01 peptide displayed a significant decrease in CDKN2A and a significant increase in COL1A1 and HAS2 compared to no treatment. (Zonari, A., et al. npj Aging, 2023)
Shown in lab studies on human skin samples and/or cells by measuring key aging biomarker, CDKN2A, and key collagen and hyaluronic acid biomarkers, COL1A1 and HAS2. Treatment with the OS-01 peptide displayed a significant decrease in CDKN2A and a significant increase in COL1A1 and HAS2 compared to no treatment. (Zonari, A., et al. npj Aging, 2023)
Related Products
Related Products
Key Takeaways:
- During and after menopause, estrogen and progesterone levels decline.
- These changing hormones reduce collagen formation, sebum, melanin, and cytokines.
- Because of these changes, menopausal skin can often be less firm, more wrinkled, dryer, and more sensitive to external pollutants.
- To prevent menopause-associated skin changes, use antioxidants, apply sunscreen, moisturize, and get sufficient sleep. You should consult your physician regarding your options with HRTs.
- OneSkin’s OS-01 peptide increases the activity of collagen and hyaluronic acid genes, COL1A1 and HAS2, helping to counteract the decreased levels of collagen and hyaluronic acid caused by menopause. This improves skin elasticity and structure, strengthens the skin barrier, and keeps the skin hydrated.
Key Takeaways:
- During and after menopause, estrogen and progesterone levels decline.
- These changing hormones reduce collagen formation, sebum, melanin, and cytokines.
- Because of these changes, menopausal skin can often be less firm, more wrinkled, dryer, and more sensitive to external pollutants.
- To prevent menopause-associated skin changes, use antioxidants, apply sunscreen, moisturize, and get sufficient sleep. You should consult your physician regarding your options with HRTs.
- OneSkin’s OS-01 peptide increases the activity of collagen and hyaluronic acid genes, COL1A1 and HAS2, helping to counteract the decreased levels of collagen and hyaluronic acid caused by menopause. This improves skin elasticity and structure, strengthens the skin barrier, and keeps the skin hydrated.
References
- https://www.ucsfhealth.org/education/the-menstrual-cycle
- https://parjournal.net/article/view/3863
- https://www.breastcancer.org/treatment-side-effects/menopause/types/testing
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802354/
- https://my.clevelandclinic.org/health/articles/16979-estrogen--hormones
- https://academic.oup.com/edrv/article/24/2/133/2424179?login=true
- https://courses.lumenlearning.com/wm-biology2/chapter/the-ovarian-cycle-the-menstrual-cycle-and-menopause/
- https://my.clevelandclinic.org/health/treatments/15245-hormone-therapy-for-menopause-symptoms
- https://parjournal.net/article/view/3863
- https://www.dermatologytimes.com/view/solution-estrogen-deficient-skin
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1549492/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836174/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772914/
- https://link.springer.com/article/10.2165/00128071-200102030-00003
- https://www.dmkskin.com.au/dmk-journal/menopause-and-the-skin/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685269/
- https://www.webmd.com/menopause/ss/slideshow-better-skin-after-menopause
- https://www.nature.com/articles/s41514-023-00109-1/figures/6
- https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.16242
References
- https://www.ucsfhealth.org/education/the-menstrual-cycle
- https://parjournal.net/article/view/3863
- https://www.breastcancer.org/treatment-side-effects/menopause/types/testing
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6802354/
- https://my.clevelandclinic.org/health/articles/16979-estrogen--hormones
- https://academic.oup.com/edrv/article/24/2/133/2424179?login=true
- https://courses.lumenlearning.com/wm-biology2/chapter/the-ovarian-cycle-the-menstrual-cycle-and-menopause/
- https://my.clevelandclinic.org/health/treatments/15245-hormone-therapy-for-menopause-symptoms
- https://parjournal.net/article/view/3863
- https://www.dermatologytimes.com/view/solution-estrogen-deficient-skin
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1549492/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836174/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772914/
- https://link.springer.com/article/10.2165/00128071-200102030-00003
- https://www.dmkskin.com.au/dmk-journal/menopause-and-the-skin/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685269/
- https://www.webmd.com/menopause/ss/slideshow-better-skin-after-menopause
- https://www.nature.com/articles/s41514-023-00109-1/figures/6
- https://onlinelibrary.wiley.com/doi/full/10.1111/jocd.16242
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Discover More
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
Discover More
Why Men Shouldn’t Ignore Skin Care: What’s Missing...
Navigating Skin Longevity: The Industry, The Scien...
What’s the Difference Between Dry and Dehydrated S...
How to Keep Your Hair Healthy and Strong During Pe...
What are Zombie Cells & How Can We Remove Them?
Collagen During Menopause: Is It Necessary For Hea...
Behind the Seal: How OneSkin Achieved the National...
Sun Sensitivity And Menopause: Protecting Your Cha...
Peptides Vs Growth Factors: Which is Better For Sk...
Hyperpigmentation and Menopause: Understanding and...
Skin Care is Health Care: Why Skin Care is the Key...
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
Does Niacinamide Help With Acne & Scarring?
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
What Causes Dark Circles Under and Around Your Eye...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging