What your skincare routine is missing (Hint. It’s a topical supplement)
4 min read
DEC 10, 2020
December 10,2020
SKIN SCIENCE
What your skincare routine is missing (Hint. It’s a topical supplement)
4 min read
DEC 10, 2020
December 10,2020
SKIN SCIENCE
Have you ever wondered, "What should I add to my skin care routine?" The truth is, the majority of skincare products out there lack scientific backing. In fact, most skin care companies formulate their products in partnership with third-party manufacturers that rarely test the efficacy of their formulas. At OneSkin, we got our start as a scientific research company dedicated to testing the effects of popular anti-aging products at the cellular level. What we discovered was shocking: most anti-aging products don’t actually work to reverse skin aging. And some even make things worse. That’s why we set out to do things differently–creating face and body skin care products backed by real scientific evidence and proven to reverse skin aging at the cellular level. The result is our collection of Topical Supplements, first-of-their-kind innovations backed by longevity research.
Have you ever wondered, "What should I add to my skin care routine?" The truth is, the majority of skincare products out there lack scientific backing. In fact, most skin care companies formulate their products in partnership with third-party manufacturers that rarely test the efficacy of their formulas. At OneSkin, we got our start as a scientific research company dedicated to testing the effects of popular anti-aging products at the cellular level. What we discovered was shocking: most anti-aging products don’t actually work to reverse skin aging. And some even make things worse. That’s why we set out to do things differently–creating face and body skin care products backed by real scientific evidence and proven to reverse skin aging at the cellular level. The result is our collection of Topical Supplements, first-of-their-kind innovations backed by longevity research.
01
What is a Topical Supplement?
You take a multivitamin every day to keep your body healthy for years to come. We think of our products in much the same way. That’s why we decided to name them Topical Supplements. Packed with our OS-01 peptide and everything your skin needs for peak longevity, our formulas are more than just skin care–they’re designed to support whole-body health starting with your largest organ (your skin!).
01
What is a Topical Supplement?
You take a multivitamin every day to keep your body healthy for years to come. We think of our products in much the same way. That’s why we decided to name them Topical Supplements. Packed with our OS-01 peptide and everything your skin needs for peak longevity, our formulas are more than just skin care–they’re designed to support whole-body health starting with your largest organ (your skin!).
02
What makes OS-01 different from other skin care actives?
Unlike other active skin care ingredients, OS-01 is proven to reverse skin aging at the cellular level, as shown in ex vivo human skin samples.* Our research on OS-01 goes far beyond what most skin care companies do. In fact, our research was recently published in npj Aging, a prestigious scientific journal. So how does OS-01 stack up against common skin care ingredients? To find out, we put OS-01 in a head-to-head test with retinol, a form of vitamin A that’s commonly considered the gold standard of anti-aging ingredients. In our tests, both OS-01 and retinol significantly increased a key biomarker associated with collagen production, COL1A1. However, only retinol also created a tenfold activity increase in a biomarker linked to aging, CDKN2A.* This shows that while retinol improves collagen production, it may increase other signs of skin aging – not what you want in an anti-aging product! You can learn more about how retinol stacks up against OS-01 here.
02
What makes OS-01 different from other skin care actives?
Unlike other active skin care ingredients, OS-01 is proven to reverse skin aging at the cellular level, as shown in ex vivo human skin samples.* Our research on OS-01 goes far beyond what most skin care companies do. In fact, our research was recently published in npj Aging, a prestigious scientific journal. So how does OS-01 stack up against common skin care ingredients? To find out, we put OS-01 in a head-to-head test with retinol, a form of vitamin A that’s commonly considered the gold standard of anti-aging ingredients. In our tests, both OS-01 and retinol significantly increased a key biomarker associated with collagen production, COL1A1. However, only retinol also created a tenfold activity increase in a biomarker linked to aging, CDKN2A.* This shows that while retinol improves collagen production, it may increase other signs of skin aging – not what you want in an anti-aging product! You can learn more about how retinol stacks up against OS-01 here.
Related Products
Related Products
03
How does OS-01 reverse aging on the cellular level?
OS-01 reverses skin aging by targeting cellular senescence*, a root cause of systemic aging. Over time and with increasing environmental exposure, our cells experience DNA damage. As this damage accumulates, they enter a state of dysfunction called senescence. Often called “zombie cells,” senescent cells secrete biochemical signals called SASP that drive healthy neighboring cells into senescence. As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning. OS-01 boosts DNA damage repair in early-stage senescent cells, preventing them from entering late-stage senescence and secreting SASP.* This stops the spread of senescence and reduces your skin’s biological age at the cellular level. The result? Healthier skin that looks, feels, and acts like younger skin for longer.
03
How does OS-01 reverse aging on the cellular level?
OS-01 reverses skin aging by targeting cellular senescence*, a root cause of systemic aging. Over time and with increasing environmental exposure, our cells experience DNA damage. As this damage accumulates, they enter a state of dysfunction called senescence. Often called “zombie cells,” senescent cells secrete biochemical signals called SASP that drive healthy neighboring cells into senescence. As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning. OS-01 boosts DNA damage repair in early-stage senescent cells, preventing them from entering late-stage senescence and secreting SASP.* This stops the spread of senescence and reduces your skin’s biological age at the cellular level. The result? Healthier skin that looks, feels, and acts like younger skin for longer.
Disclaimers
* Shown in lab studies on human skin cells and/or samples (Zonari, et al., 2023)
Disclaimers
* Shown in lab studies on human skin cells and/or samples (Zonari, et al., 2023)
04
What can I expect from OneSkin Topical Supplements?
Backed by both lab and clinical testing to validate their benefits, our Topical Supplements harness the power of OS-01 to extend your skin longevity. Here’s a quick look at how the age-reversing action of OS-01 shows up on your skin.
04
What can I expect from OneSkin Topical Supplements?
Backed by both lab and clinical testing to validate their benefits, our Topical Supplements harness the power of OS-01 to extend your skin longevity. Here’s a quick look at how the age-reversing action of OS-01 shows up on your skin.
OS-01 FACE
OS-01 FACE
OS-01 EYE
OS-01 EYE
OS-01 BODY
OS-01 BODY
05
How does OS-01 Work with Different Skin Types
The OS-01 peptide revolutionizes skin care routines for individuals with varying skin types, from normal skin to acne-prone skin, and even sensitive or combination skin. Recognizing that different skin types have unique needs, our Topical Supplements cater to the demands of oily skin by balancing excess sebum production, while simultaneously providing essential hydration to combat dry skin concerns. For those navigating the intricacies of combination skin, OS-01 ensures balanced care for each skin zone. And, if you're exploring options for combating aging skin, OS-01 offers a comprehensive approach by targeting skin cells at the cellular level, reversing the signs of aging without compromising the delicate balance of the skin barrier.If you’re wondering "what should I add to my skin care routine?", OS-01 emerges as the answer, promoting healthier skin. For those leading busy lives or with unpredictable schedules, our travel-size skin care products provide convenient solutions to maintain your routine on the go.With OneSkin, achieving glowing skin becomes a natural outcome of our comprehensive and tailored approach to skin care, irrespective of your skin type or specific skin concerns.
05
How does OS-01 Work with Different Skin Types
The OS-01 peptide revolutionizes skin care routines for individuals with varying skin types, from normal skin to acne-prone skin, and even sensitive or combination skin. Recognizing that different skin types have unique needs, our Topical Supplements cater to the demands of oily skin by balancing excess sebum production, while simultaneously providing essential hydration to combat dry skin concerns. For those navigating the intricacies of combination skin, OS-01 ensures balanced care for each skin zone. And, if you're exploring options for combating aging skin, OS-01 offers a comprehensive approach by targeting skin cells at the cellular level, reversing the signs of aging without compromising the delicate balance of the skin barrier.If you’re wondering "what should I add to my skin care routine?", OS-01 emerges as the answer, promoting healthier skin. For those leading busy lives or with unpredictable schedules, our travel-size skin care products provide convenient solutions to maintain your routine on the go.With OneSkin, achieving glowing skin becomes a natural outcome of our comprehensive and tailored approach to skin care, irrespective of your skin type or specific skin concerns.
Key Takeaways:
- Most skin care is backed by very little scientific evidence.
- Powered by our OS-01 peptide, our Topical Supplements are fundamentally different because they don’t just address surface-level signs of skin aging, they extend skin longevity.
- Proven to reverse skin aging at the cellular level, OS-01 has been shown to outperform retinol, skin care’s most common anti-aging ingredient.
- OS-01 reverses skin aging by targeting cellular senescence, a root cause of aging throughout our bodies.
- In clinical studies, the benefits of OS-01 appear as firmer skin, diminished wrinkles, improved tone and more.
- OS-01’s benefits may support whole-body wellbeing by reducing a key marker of systemic aging in the body’s largest organ.
Key Takeaways:
- Most skin care is backed by very little scientific evidence.
- Powered by our OS-01 peptide, our Topical Supplements are fundamentally different because they don’t just address surface-level signs of skin aging, they extend skin longevity.
- Proven to reverse skin aging at the cellular level, OS-01 has been shown to outperform retinol, skin care’s most common anti-aging ingredient.
- OS-01 reverses skin aging by targeting cellular senescence, a root cause of aging throughout our bodies.
- In clinical studies, the benefits of OS-01 appear as firmer skin, diminished wrinkles, improved tone and more.
- OS-01’s benefits may support whole-body wellbeing by reducing a key marker of systemic aging in the body’s largest organ.
References
- https://askwonder.com/research/cosmetic-brands-case-studies-part-2-z53gwn5n9
- https://pubmed.ncbi.nlm.nih.gov/22052267/
- https://pubmed.ncbi.nlm.nih.gov/29495517/
- https://pubmed.ncbi.nlm.nih.gov/22361190/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257951/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921764/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910557/
References
- https://askwonder.com/research/cosmetic-brands-case-studies-part-2-z53gwn5n9
- https://pubmed.ncbi.nlm.nih.gov/22052267/
- https://pubmed.ncbi.nlm.nih.gov/29495517/
- https://pubmed.ncbi.nlm.nih.gov/22361190/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4257951/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921764/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4910557/
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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Unlocking the Science of Wrinkles: Causes, Formati...
PREP enhances the effects of OS-01 FACE, and the p...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Ceramides For Skin: Everything You Need to Know ne...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What Are The Causes Of Dry, Flaky Skin On Your Fac...
What is the Best Skin Care Regimen for Aging Skin?
7 Benefits of Jojoba Oil
What happens to skin as a person ages?
What are the Benefits of Sulforaphane?
8 Benefits of Andiroba Oil For Skin
Invasive vs. Non-Invasive Skincare: The pros and c...
Allantoin For Skin: A Comprehensive Guide
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
How OneSkin Developed the OS-01 Peptide
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
3 Skin Tightening Ingredients To Help Boost Skin H...
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging