OS-01 FACE Topical Supplement Refill
- Unit price
- per
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- Suited to All skin types, safe for sensitive skin
- Targets Dehydration, dullness, loss of elasticity
- Format Lightweight moisturizer
**Reusable plastic shell not included**
The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.
Benefits
Multitasking moisturizer that addresses the common signs of aging on areas exposed most to the environment
Hydration
Boosts barrier function, allowing your skin retain moisture and stay hydrated.02
Firmness
Switches off the cells that degrade collagen, helping skin stay firm.01,03
Radiance
Enhances skin tone and texture, helping skin look and feel smooth and radiant.02
5-STAR REVIEWS
See why customers love OS-01 FACE
βI stopped using retinol which caused me to have rough, red patches, but kept my skin supple and smoothβ¦and now using OneSkin I still have the wrinkle reduction effects and smooth skin without the negative effects.β β Tova N.
"I love this science-backed product. It truly makes a difference to my skin and has allowed me to pare down all the other lotions, potions, & products that were more reactive in nature vs this proactive approach. Not only have I saved money on my skincare routine, but I've witnessed even skin tone, more elasticity, and a reduction in forehead wrinkles. Would recommend again and again. Can't wait to see what they think of next!" β Laura E.
"Itβs working great!!! It absorbs quickly. I see and feel a significant difference in my skinβs texture and radiance. My skin looks smoother and feels firmer. I highly recommend it for anyone serious about maintaining youthful, healthy glowing skin." β Ildiko C.
"One skin really loves my skin. I no longer use retinoids and put up with their side effects. One skin feels so effective as it absorbs quickly leaving my skin more even, bouncy and fresh." β Sarah B.
The proof is in the pictures
CLINICAL DATA
Visible results, scientifically validated
100
of participants had improved smoothness 02
95.5
of participants had improved firmness, radiance, and tone 02
90
of participants had improved elasticity 02
86
of participants had improved appearance of fine lines and wrinkles 02
The Science Behind OS-01 FACE
With age, skin becomes thinner, produces less collagen, proliferates at a slower rate, and accumulates damage. By analyzing key aging biomarkers in human skin samples before and after treatment in the lab, our scientists found that OS-01 FACE:
- Increases epidermal thickness 01
- Supports collagen biosynthesis pathways (increase in COL1A1 and collagen levels) 01,03
- Promotes cellular proliferation (increase in MKI67) 01
Expression of biomarkers associated with collagen production (COL1A1) and cell proliferation (MKi67) in the dermis of ex vivo human skin samples following treatment with nothing (No Treatment) or OS-01 FACE. (Zonari, A., et al. npj Aging, 2023) Note: In npj Aging publication, "Topical Pep 14" = OS-01 FACE
6 active ingredients that complement the OS-01 peptide
Getting started with OS-01 FACE
Follow these easy steps for optimal results
- Dispense 1-2 pumps onto fingers
- Gently massage into skin on the face and neck
- Use 2 times daily
How it works
Powered by the OS-01 Senescence Peptideβ’
The only peptide scientifically proven to reverse skin aging at the cellular levelΒ 01,02,03
All Ingredients
Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.
Citations
01 Zonari, A., et al. Senotherapeutic peptide treatment reduces biological age Β and senescence burden in human skin models. npj Aging, 9(1), 1-15. 2023. doi:10.1038/s41514-023-00109-1
02 Zonari A., et al. Double-blind, vehicle-controlled clinical investigation of peptide OS-01 for skin rejuvenation. J Cosmet Dermatol. 2024; 23: 2135-2144. doi:10.1111/jocd.16242
03 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin or hair cells in the OneSkin lab. Explore more at oneskin.co/claims
OS-01 FACE Topical Supplement Refill
- Rachel R.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 starsBest Skin Product Iβve Used
My skin is glowing. Iβve been using OS1 for a few months and continue to be impressed. My skin feels so hydrated but not oily, even in the dry Denver climate.
- Jennifer T.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 starsJennifer
I love the product.
- Amy A.Verified BuyerReviewingOS-01 FACE Refill PouchI recommend this productRated 5 out of 5 starsReview
Im giving it 5 stars but I just wish it was cheaper
OneSkin7 hours agoHi Amy!
Thank you for the review! We are happy to hear you are enjoying OS-01 FACE!
- Linda D.Verified BuyerRated 4 out of 5 starsOne skin face cream
Results good but would like more moisture because I have very dry skin.
OneSkin7 hours agoHi Linda!
Thank you for the review!
To date, it has been well-tolerated by our customers, but we are all unique and can experience changes in routine differently. Results can vary from person to person and can be affected by many things such as genetics, diet, exercise, age, environmental factors, etc. Another thing we'd like to note is while results may not be seen externally, there are many benefits from our peptides that work internally to help the skin.
To start, could you please advise on the following at your convenience:- Sometimes in different climates, our skin can become drier than normal so you can try adding an additional moisturizer after OS-01 to boost the amount of moisture your skin is receiving.
- Try only using OneSkin products in your routine for a few weeks to see if you notice any changes!
Feel free to reach out to support@oneskin.co for more personalized advice!
- Diane N.Verified BuyerRated 3 out of 5 starsNice moisturizer but not sure about results
I just finished the 1.7 oz bottle, which I used consistently over the past month. The product feels niceβlight, airy, and has a soft oatmeal-like scent thatβs pleasant and not overpowering. It applies well and absorbs easily, so I do appreciate the texture and experience of using it.
That said, at $120 ($117 for the refill), itβs quite an investment. Thereβs minimal savings unless you subscribe, and Iβm not sure I want to commit without seeing stronger results.
I didnβt notice a meaningful difference in my skin after a full bottleβno visible thickening or major improvement in texture or firmness. Maybe it takes more time, but Iβm hesitant to spend another $100+ just to find out. For now, I think Iβll return to my regular Inkey List moisturizersβtheyβre much more affordable and seem to work just as well for me.
Itβs a lovely cream, just not a game-changer for my skin or budget.
OneSkin7 hours agoThank you for the review, Diane!
To date, it has been well-tolerated by our customers, but we are all unique and can experience changes in routine differently. Results can vary from person to person and can be affected by many things such as genetics, diet, exercise, age, environmental factors, etc. Another thing we'd like to note is while results may not be seen externally, there are many benefits from our peptides that work internally to help the skin.
To start, could you please advise on the following at your convenience:- Sometimes in different climates, our skin can become drier than normal so you can try adding an additional moisturizer after OS-01 to boost the amount of moisture your skin is receiving.
- Try only using OneSkin products in your routine for a few weeks to see if you notice any changes!
Feel free to reach out to support@oneskin.co for more personalized advice!
