How The OneSkin Products Work Synergistically
10 min read
September 13,2024
ONESKIN PRODUCTS
How The OneSkin Products Work Synergistically
10 min read
September 13,2024
ONESKIN PRODUCTS
Skincare routines have long relied on the classic cleanse-tone-moisturize trio. We've all followed these steps, but have you ever wondered if using these products together truly benefits your skin?Science shows that effective skin care goes beyond mixing and matching products from various brands. It's about synergy. That’s why the OneSkin Longevity System is meticulously formulated and scientifically validated to work in harmony, battling aging at the cellular level from head to toe.Still skeptical? Let us walk you through the science behind our unique system.
Skincare routines have long relied on the classic cleanse-tone-moisturize trio. We've all followed these steps, but have you ever wondered if using these products together truly benefits your skin?Science shows that effective skin care goes beyond mixing and matching products from various brands. It's about synergy. That’s why the OneSkin Longevity System is meticulously formulated and scientifically validated to work in harmony, battling aging at the cellular level from head to toe.Still skeptical? Let us walk you through the science behind our unique system.
01
Step 01: Cleanse And Exfoliate With PREP
When we set out to create our daily cleanser, we aimed for more than just removing impurities. That’s why PREP is formulated with gentle yet effective chemical exfoliators like prickly pear extract; these ingredients not only clear away dead skin cells but also enhance your skin's absorption of subsequent products. PREP was rigorously tested in the OneSkin lab to confirm its ability to boost the effects of OS-01 FACE. The results were unequivocal.
PREP Doubles The Absorption of The OS-01 Peptide
The OS-01 peptide is the first peptide proven to reverse the skin’s biological age.(1,2) The OneSkin Lab found cleansing with PREP before using OS-01 FACE increases the absorption of the peptide by 2.2X.(1)This means that using PREP prior to OS-01 FACE could more than double the peptide penetration. With a higher peptide concentration in the deeper layers of your skin, you should experience enhanced effects from using OS-01 FACE.
01
Step 01: Cleanse And Exfoliate With PREP
When we set out to create our daily cleanser, we aimed for more than just removing impurities. That’s why PREP is formulated with gentle yet effective chemical exfoliators like prickly pear extract; these ingredients not only clear away dead skin cells but also enhance your skin's absorption of subsequent products. PREP was rigorously tested in the OneSkin lab to confirm its ability to boost the effects of OS-01 FACE. The results were unequivocal.
PREP Doubles The Absorption of The OS-01 Peptide
The OS-01 peptide is the first peptide proven to reverse the skin’s biological age.(1,2) The OneSkin Lab found cleansing with PREP before using OS-01 FACE increases the absorption of the peptide by 2.2X.(1)This means that using PREP prior to OS-01 FACE could more than double the peptide penetration. With a higher peptide concentration in the deeper layers of your skin, you should experience enhanced effects from using OS-01 FACE.
Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all.
Shown by comparing the amount of the OS-01 peptide present in the dermis layer of ex vivo human skin samples exposed to OS-01 FACE and pre-cleansed with PREP versus not pre-cleansed at all.
PREP Enhances The Hydration Effects of OS-01 FACE
AQP3 is a key gene involved in skin hydration. When measured in ex vivo skin before and after treatment, using PREP in combination with OS-01 FACE improved AQP3 activity by 40%, compared to OS-01 FACE alone.(1)This means that using PREP before OS-01 FACE makes your skin even better equipped to maintain optimal hydration.
PREP Enhances The Hydration Effects of OS-01 FACE
AQP3 is a key gene involved in skin hydration. When measured in ex vivo skin before and after treatment, using PREP in combination with OS-01 FACE improved AQP3 activity by 40%, compared to OS-01 FACE alone.(1)This means that using PREP before OS-01 FACE makes your skin even better equipped to maintain optimal hydration.
Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment in 46-year-old ex vivo human skin samples with PREP+ OS-01 FACE vs OS-01 FACE alone.
Shown by comparing the activity of a key biomarker associated with skin hydration (AQP3) before and after treatment in 46-year-old ex vivo human skin samples with PREP+ OS-01 FACE vs OS-01 FACE alone.
02
Step 02: Use OS-01 EYE To Slow Aging Near The Eyes
Considering that the skin around your eyes ages faster than the skin on the rest of your face, it's a shame that most skin care systems don't include a dedicated eye cream.(3) To combat accelerated aging around the eyes, we created our most potent product - OS-01 EYE.Formulated with the highest concentration of the OS-01 peptide and other star ingredients like Argirilene and CoQ10, OS-01 EYE specifically addresses the needs of the eye area.Read more about how our OS-01 EYE is distinct from OS-01 FACE here.
OS-01 EYE Doubles Collagen In The Dermal Layer
By measuring collagen levels in ex vivo human eyelid samples, we found that OS-01 EYE improves collagen levels by 2.3x in the dermis.(1)By improving collagen in this structural skin layer, OS-01 EYE helps the thin skin around the eyes resist accelerated age-related collagen loss, leading to firmer, more radiant and elastic skin.
02
Step 02: Use OS-01 EYE To Slow Aging Near The Eyes
Considering that the skin around your eyes ages faster than the skin on the rest of your face, it's a shame that most skin care systems don't include a dedicated eye cream.(3) To combat accelerated aging around the eyes, we created our most potent product - OS-01 EYE.Formulated with the highest concentration of the OS-01 peptide and other star ingredients like Argirilene and CoQ10, OS-01 EYE specifically addresses the needs of the eye area.Read more about how our OS-01 EYE is distinct from OS-01 FACE here.
OS-01 EYE Doubles Collagen In The Dermal Layer
By measuring collagen levels in ex vivo human eyelid samples, we found that OS-01 EYE improves collagen levels by 2.3x in the dermis.(1)By improving collagen in this structural skin layer, OS-01 EYE helps the thin skin around the eyes resist accelerated age-related collagen loss, leading to firmer, more radiant and elastic skin.
Shown in ex vivo human eyelid skin samples from a 70 yo male donor, by measuring collagen levels in the dermis before (Control) and after treatment with OS-01 EYE. Data measured in triplicate and normalized to control. The collagen density was determined by quantifying Masson's Trichrome staining.
Shown in ex vivo human eyelid skin samples from a 70 yo male donor, by measuring collagen levels in the dermis before (Control) and after treatment with OS-01 EYE. Data measured in triplicate and normalized to control. The collagen density was determined by quantifying Masson's Trichrome staining.
OS-01 EYE Decreases Biomarkers Associated with Inflammation, Aging, and Senescence
Studies have shown that the skin around the eyes shows increased levels of a biomarker called CDKN2A, which is associated with skin aging and cellular senescence.(5)In Oneskins tests, OS-01 EYE was proven to reduce that exact marker–CDKN2A– in ex vivo human skin samples. OS-01 EYE also reduces IL-8, another marker associated with increased levels of inflammation, one of the 12 hallmarks of aging.(1)
OS-01 EYE Decreases Biomarkers Associated with Inflammation, Aging, and Senescence
Studies have shown that the skin around the eyes shows increased levels of a biomarker called CDKN2A, which is associated with skin aging and cellular senescence.(5)In Oneskins tests, OS-01 EYE was proven to reduce that exact marker–CDKN2A– in ex vivo human skin samples. OS-01 EYE also reduces IL-8, another marker associated with increased levels of inflammation, one of the 12 hallmarks of aging.(1)
Shown in ex vivo human eyelid skin (42, 59, and 84 yo) before and after treatment with OS-01 EYE, analyzed/ for expression of key aging and senescence biomarker (CDKN2A) and inflammation biomarker (IL-8).
Shown in ex vivo human eyelid skin (42, 59, and 84 yo) before and after treatment with OS-01 EYE, analyzed/ for expression of key aging and senescence biomarker (CDKN2A) and inflammation biomarker (IL-8).
By improving skin health at the cellular level, OS-01 EYE results in visible skin changes around the eyes, including:
- Improved skin elasticity (Shown in 86% of users)*
- Improved hydration (Avg improvement of +32%)*
- Skin barrier (Avg improvement of +17%)*
- Improved overall appearance (Shown in 96% of users)*
By improving skin health at the cellular level, OS-01 EYE results in visible skin changes around the eyes, including:
- Improved skin elasticity (Shown in 86% of users)*
- Improved hydration (Avg improvement of +32%)*
- Skin barrier (Avg improvement of +17%)*
- Improved overall appearance (Shown in 96% of users)*
03
Step 03: Use OS-01 FACE To Support Epidermal Thickness & Collagen Production
At the heart of any complete skincare system is a quality moisturizer. However, Oneskins' flagship product, OS-01 FACE, is so much more than that.OS-01 FACE is formulated to address signs of aging in the most vulnerable and exposed areas of your skin, like the face, neck, and hands.
OS-01 FACE Increases Epidermal Thickness
Epidermal thickness plays a crucial role in maintaining the youthful appearance and overall health of your skin. Skin naturally thins with age, leading to a loss of elasticity and increased fragility, making epidermal thickness one of the most essential elements of skin longevity. OS-01 FACE is scientifically proven to increase epidermal thickness, translating to smoother, more youthful-looking skin.
03
Step 03: Use OS-01 FACE To Support Epidermal Thickness & Collagen Production
At the heart of any complete skincare system is a quality moisturizer. However, Oneskins' flagship product, OS-01 FACE, is so much more than that.OS-01 FACE is formulated to address signs of aging in the most vulnerable and exposed areas of your skin, like the face, neck, and hands.
OS-01 FACE Increases Epidermal Thickness
Epidermal thickness plays a crucial role in maintaining the youthful appearance and overall health of your skin. Skin naturally thins with age, leading to a loss of elasticity and increased fragility, making epidermal thickness one of the most essential elements of skin longevity. OS-01 FACE is scientifically proven to increase epidermal thickness, translating to smoother, more youthful-looking skin.
Epidermal thickness analysis of ex vivo skin samples (35, 55 and 79 yo) maintained in basal media, or treated with OS-01 FACE for 5 days. (Zonari, et al., 2023)
Epidermal thickness analysis of ex vivo skin samples (35, 55 and 79 yo) maintained in basal media, or treated with OS-01 FACE for 5 days. (Zonari, et al., 2023)
OS-01 FACE Supports Collagen Biosynthesis and Cellular Proliferation
In a lab study examining the dermis of ex vivo human skin samples, we found that topical treatment with OS-01 FACE significantly increased COL1A1, a key collagen production biomarker.(1,2)OS-01 FACE also increased a key marker associated with cell proliferation, MKI67.(1,2) This data indicates that OS-01 can support the growth of more collagen-producing cells, which likely contributes to an overall increase in collagen production.
OS-01 FACE Supports Collagen Biosynthesis and Cellular Proliferation
In a lab study examining the dermis of ex vivo human skin samples, we found that topical treatment with OS-01 FACE significantly increased COL1A1, a key collagen production biomarker.(1,2)OS-01 FACE also increased a key marker associated with cell proliferation, MKI67.(1,2) This data indicates that OS-01 can support the growth of more collagen-producing cells, which likely contributes to an overall increase in collagen production.
Shown in ex vivo human skin samples (35, 55, and 79 yo) topically treated with OS-01 FACE, then analyzed for expression of key collagen production biomarker (COL1A1) and cell proliferation biomarker (MKI67). (Zonari, et al., 2023)
Shown in ex vivo human skin samples (35, 55, and 79 yo) topically treated with OS-01 FACE, then analyzed for expression of key collagen production biomarker (COL1A1) and cell proliferation biomarker (MKI67). (Zonari, et al., 2023)
By improving collagen & epidermal thickness in skin that’s vulnerable to damage, OS-01 FACE was clinically validated to provide visible improvements, including:(1,6)
- Improved skin smoothness & overall appearance (Shown in 100% of users)*
- Improved skin evenness, radiance, pores, & firmness (shown in 95.5% of users)*
- Improved skin elasticity (Shown in 90% of users)*
- Diminished appearance of fine lines & wrinkles (Shown in 87% of users)*
By improving collagen & epidermal thickness in skin that’s vulnerable to damage, OS-01 FACE was clinically validated to provide visible improvements, including:(1,6)
- Improved skin smoothness & overall appearance (Shown in 100% of users)*
- Improved skin evenness, radiance, pores, & firmness (shown in 95.5% of users)*
- Improved skin elasticity (Shown in 90% of users)*
- Diminished appearance of fine lines & wrinkles (Shown in 87% of users)*
04
Step 04: OS-01 FACE SPF Protects Against Future UV Aging and Can Undo Effects of Past UV Aging
While OS-01 FACE is an unprecedented solution to intrinsic skin aging, sunscreen is still the most effective way to prevent future extrinsic aging from UV. After all, long-term damage from UV exposure can trigger up to 90% of the visible signs of aging. That’s why OneSkin offers OS-01 FACE SPF - a 100% non-nano mineral sunscreen specifically designed for delicate facial skin. OS-01 FACE SPF also contains the OS-01 peptide; however, the penetration of the peptide is naturally inhibited by zinc oxide, our preferred UV filter. Therefore, to reap the full benefit of the OS-01 peptide, we recommend using OS-01 FACE as your daily facial moisturizer and OS-01 FACE SPF as your daily facial SPF. In fact, using OS-01 FACE SPF & OS-01 FACE together enhances the effects of the OS-01 peptide.
OS-01 FACE SPF Prevents UV-induced Skin Damage with Non-nano Zinc Oxide
When used in conjunction with OS-01 FACE, OS-01 FACE SPF significantly reduces the expression of key biomarkers associated with aging.(1)
04
Step 04: OS-01 FACE SPF Protects Against Future UV Aging and Can Undo Effects of Past UV Aging
While OS-01 FACE is an unprecedented solution to intrinsic skin aging, sunscreen is still the most effective way to prevent future extrinsic aging from UV. After all, long-term damage from UV exposure can trigger up to 90% of the visible signs of aging. That’s why OneSkin offers OS-01 FACE SPF - a 100% non-nano mineral sunscreen specifically designed for delicate facial skin. OS-01 FACE SPF also contains the OS-01 peptide; however, the penetration of the peptide is naturally inhibited by zinc oxide, our preferred UV filter. Therefore, to reap the full benefit of the OS-01 peptide, we recommend using OS-01 FACE as your daily facial moisturizer and OS-01 FACE SPF as your daily facial SPF. In fact, using OS-01 FACE SPF & OS-01 FACE together enhances the effects of the OS-01 peptide.
OS-01 FACE SPF Prevents UV-induced Skin Damage with Non-nano Zinc Oxide
When used in conjunction with OS-01 FACE, OS-01 FACE SPF significantly reduces the expression of key biomarkers associated with aging.(1)
The expression of biomarkers associated with aging, P16 and IL-8, were measured on ex vivo human skin samples before treatment and after treatment with OS-01 FACE alone, or OS-01 FACE then OS-01 FACE SPF (formerly OS-01 SHIELD).
The expression of biomarkers associated with aging, P16 and IL-8, were measured on ex vivo human skin samples before treatment and after treatment with OS-01 FACE alone, or OS-01 FACE then OS-01 FACE SPF (formerly OS-01 SHIELD).
OS-01 FACE SPF Neutralizes Free Radicals
UV filters are just the first part of the sun protection puzzle. Antioxidants, molecules that prevent oxidation, play a crucial role in protecting your skin from the tissue-damaging effects of UV radiation. That’s why OS-01 FACE SPF is formulated with five highly potent antioxidants: stabilized vitamin C, green tea extract, acai extract, tara fruit extracts, and sunflower sprouts. Oneskin’s scientists tested the effectiveness of OS-01 FACE SPF in neutralizing free radicals using a chemical probe with a stable radical. The results were clear: OS-01 FACE SPF neutralizes free radicals at least 4X more effectively than leading anti-aging SPFs.(1)
OS-01 FACE SPF Neutralizes Free Radicals
UV filters are just the first part of the sun protection puzzle. Antioxidants, molecules that prevent oxidation, play a crucial role in protecting your skin from the tissue-damaging effects of UV radiation. That’s why OS-01 FACE SPF is formulated with five highly potent antioxidants: stabilized vitamin C, green tea extract, acai extract, tara fruit extracts, and sunflower sprouts. Oneskin’s scientists tested the effectiveness of OS-01 FACE SPF in neutralizing free radicals using a chemical probe with a stable radical. The results were clear: OS-01 FACE SPF neutralizes free radicals at least 4X more effectively than leading anti-aging SPFs.(1)
Utilizing a chemical probe with a stable radical that changes colors when that radical is scavenged, levels of free radical scavenging were measured for various leading SPFs and OS-01 SHIELD.
Utilizing a chemical probe with a stable radical that changes colors when that radical is scavenged, levels of free radical scavenging were measured for various leading SPFs and OS-01 SHIELD.
05
Step 05: OS-01 BODY Pauses Biological Aging
Most skin care systems focus on the skin on your face. But about 97% of our skin is below your neck! To adequately address bodily longevity, Oneskin’s system includes OS-01 BODY, our topical supplement designed to improve the health of your largest vital organ. In an unprecedented clinical study, Oneskins scientists were delighted to find that OS-01 BODY successfully paused overall biological aging and reduced a key inflammation biomarker in the blood, pointing to the important role that skin plays in overall inflammation and longevity.(1)
OS-01 BODY Increases Epidermal Thickness
As your skin ages, the epidermis begins to thin. One study found that it thins at a rate of about 5-7% per decade.(8) This can lead to common signs of aging on the body, including crepiness and skin laxity. To guarantee that OS-01 BODY improved these common signs of aging, Oneskin scientists analyzed whether it could increase epidermal thickness in the lab.Compared to skin that was not treated, ex vivo human skin samples treated with OS-01 BODY showed up to a 40% increase in epidermal thickness.(1) This improved skin thickness can lead to a reduced appearance of crepey skin and an improved feeling of skin hydration.
05
Step 05: OS-01 BODY Pauses Biological Aging
Most skin care systems focus on the skin on your face. But about 97% of our skin is below your neck! To adequately address bodily longevity, Oneskin’s system includes OS-01 BODY, our topical supplement designed to improve the health of your largest vital organ. In an unprecedented clinical study, Oneskins scientists were delighted to find that OS-01 BODY successfully paused overall biological aging and reduced a key inflammation biomarker in the blood, pointing to the important role that skin plays in overall inflammation and longevity.(1)
OS-01 BODY Increases Epidermal Thickness
As your skin ages, the epidermis begins to thin. One study found that it thins at a rate of about 5-7% per decade.(8) This can lead to common signs of aging on the body, including crepiness and skin laxity. To guarantee that OS-01 BODY improved these common signs of aging, Oneskin scientists analyzed whether it could increase epidermal thickness in the lab.Compared to skin that was not treated, ex vivo human skin samples treated with OS-01 BODY showed up to a 40% increase in epidermal thickness.(1) This improved skin thickness can lead to a reduced appearance of crepey skin and an improved feeling of skin hydration.
Epidermal thickness analysis of ex vivo skin sample from a 44 year old donor measured before and after treatment with OS-01 BODY. Data measured in triplicate and normalized to control.
Epidermal thickness analysis of ex vivo skin sample from a 44 year old donor measured before and after treatment with OS-01 BODY. Data measured in triplicate and normalized to control.
06
Step 06: OS-01 BODY SPF Protects Against UV Aging
Before you step into the sun, the skin on your body still faces the most significant source of extrinsic aging: UV radiation. OS-01 BODY SPF is a crucial part of Oneskin’s longevity system, specifically for the skin on your body to reduce both intrinsic and extrinsic sources of aging.
OS-01 BODY SPF Reduces The Effects of UV Aging
To understand how OS-01 BODY SPF mitigates skin aging, Oneskin scientists analyzed ex vivo human skin samples treated with the product versus a control after UVB exposure. Results showed OS-01 BODY SPF reduced key aging biomarkers p16 and IL-8.(1)OS-01 BODY SPF also mitigated hyaluronic acid and collagen degradation by lowering HYAL1 and MMP-1 levels.(1) This demonstrates that the formulation, containing non-nano zinc oxide, the OS-01 peptide, and potent antioxidants, effectively reduces the detrimental effects of UV exposure on skin aging by targeting multiple aging pathways.
06
Step 06: OS-01 BODY SPF Protects Against UV Aging
Before you step into the sun, the skin on your body still faces the most significant source of extrinsic aging: UV radiation. OS-01 BODY SPF is a crucial part of Oneskin’s longevity system, specifically for the skin on your body to reduce both intrinsic and extrinsic sources of aging.
OS-01 BODY SPF Reduces The Effects of UV Aging
To understand how OS-01 BODY SPF mitigates skin aging, Oneskin scientists analyzed ex vivo human skin samples treated with the product versus a control after UVB exposure. Results showed OS-01 BODY SPF reduced key aging biomarkers p16 and IL-8.(1)OS-01 BODY SPF also mitigated hyaluronic acid and collagen degradation by lowering HYAL1 and MMP-1 levels.(1) This demonstrates that the formulation, containing non-nano zinc oxide, the OS-01 peptide, and potent antioxidants, effectively reduces the detrimental effects of UV exposure on skin aging by targeting multiple aging pathways.
Ex vivo human skin samples (41y and 59y) that were treated with nothing (No Treatment) or OS-01 BODY SPF were exposed to 1J/cm2 UVB radiation, then the gene expression levels were analyzed after 24 hours.
Ex vivo human skin samples (41y and 59y) that were treated with nothing (No Treatment) or OS-01 BODY SPF were exposed to 1J/cm2 UVB radiation, then the gene expression levels were analyzed after 24 hours.
Related Products
Related Products
07
How to Use Oneskin’s Complete System Together
While the OneSkin system contains everything you need, some people prefer to integrate it with their existing routines. Here’s your guide for getting the application order just right.
Morning:
- Use PREP to cleanse
- Apply OS-01 EYE by gently tapping one pump in a semi-circle around each eye
- Follow with OS-01 FACE. Allow both OS-01 EYE and OS-01 FACE to dry
- Apply OS-01 FACE SPF and OS-01 BODY SPF to exposed areas
- You can follow up with your choice of makeup
07
How to Use Oneskin’s Complete System Together
While the OneSkin system contains everything you need, some people prefer to integrate it with their existing routines. Here’s your guide for getting the application order just right.
Morning:
- Use PREP to cleanse
- Apply OS-01 EYE by gently tapping one pump in a semi-circle around each eye
- Follow with OS-01 FACE. Allow both OS-01 EYE and OS-01 FACE to dry
- Apply OS-01 FACE SPF and OS-01 BODY SPF to exposed areas
- You can follow up with your choice of makeup
Evening:
- Cleanse with PREP to remove your SPF and makeup
- Double cleanse (optional)
- Apply OS-01 EYE
- Follow with OS-01 FACE
- If you've worn OS-01 BODY SPF, shower before applying OS-01 BODY to clean body skin (damp or dry) and massage until absorbed
Evening:
- Cleanse with PREP to remove your SPF and makeup
- Double cleanse (optional)
- Apply OS-01 EYE
- Follow with OS-01 FACE
- If you've worn OS-01 BODY SPF, shower before applying OS-01 BODY to clean body skin (damp or dry) and massage until absorbed
Evening:
- Cleanse with PREP to remove your SPF and makeup
- Double cleanse (optional)
- Apply OS-01 EYE
- Follow with OS-01 FACE
- If you've worn OS-01 BODY SPF, shower before applying OS-01 BODY to clean body skin (damp or dry) and massage until absorbed
Evening:
- Cleanse with PREP to remove your SPF and makeup
- Double cleanse (optional)
- Apply OS-01 EYE
- Follow with OS-01 FACE
- If you've worn OS-01 BODY SPF, shower before applying OS-01 BODY to clean body skin (damp or dry) and massage until absorbed
Key Takeaways:
- Unlike many skin care systems, OneSkin products were specifically formulated to work better together.
- Using PREP before OS-01 FACE has been scientifically proven to double the penetration of the OS-01 peptide so you get maximum benefits from every drop.
- At the heart of our system is OS-01 FACE, the daily moisturizer proven to address the effects of sun damage on areas most exposed to the sun.
- Plus, our system contains a body cream to support longevity in the 97% of skin that’s not on your face or neck.
Key Takeaways:
- Unlike many skin care systems, OneSkin products were specifically formulated to work better together.
- Using PREP before OS-01 FACE has been scientifically proven to double the penetration of the OS-01 peptide so you get maximum benefits from every drop.
- At the heart of our system is OS-01 FACE, the daily moisturizer proven to address the effects of sun damage on areas most exposed to the sun.
- Plus, our system contains a body cream to support longevity in the 97% of skin that’s not on your face or neck.
Disclaimers
- This article was initially published in January 2023 and has been updated.
Disclaimers
- This article was initially published in January 2023 and has been updated.
References
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- https://www.nature.com/articles/s41514-023-00109-1
- https://www.jaad.org/article/S0190-9622(16)00242-5/fulltext
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268288/
- https://doi.org/10.1016/j.jaad.2016.02.112
- https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16242
- https://pubmed.ncbi.nlm.nih.gov/10048311/
- https://pubmed.ncbi.nlm.nih.gov/2384222/
References
- Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
- https://www.nature.com/articles/s41514-023-00109-1
- https://www.jaad.org/article/S0190-9622(16)00242-5/fulltext
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268288/
- https://doi.org/10.1016/j.jaad.2016.02.112
- https://onlinelibrary.wiley.com/doi/epdf/10.1111/jocd.16242
- https://pubmed.ncbi.nlm.nih.gov/10048311/
- https://pubmed.ncbi.nlm.nih.gov/2384222/
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
Reviewed by Alessandra Zonari, PhD, Chief Scientific Officer (CSO) and Co-Founder of OneSkin
Alessandra earned her Master’s degree in stem cell biology, and her PhD in skin regeneration and tissue engineering at the Federal University of Minas Gerais in Brazil in collaboration with the 3B’s Research Group in Portugal. Alessandra did a second post-doctoral at the University of Coimbra in Portugal. She is a co-inventor of three patents and has published 20 peer-reviewed papers in scientific journals.
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Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
Navigating Anti-Aging Skincare: The industry, the ...
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
3 Skin Tightening Ingredients To Help Boost Skin H...
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What is the Best Skin Care Regimen for Aging Skin?
What happens to skin as a person ages?
What Causes Dark Circles Under and Around Your Eye...
Invasive vs. Non-Invasive Skincare: The pros and c...
6 Benefits of Jojoba Oil
What are the Benefits of Sulforaphane?
What is Sustainable Packaging for Cosmetic Product...
7 Benefits of Andiroba Oil For Skin
What Are The Causes Of Dry, Flaky Skin On Your Fac...
PREP enhances the effects of OS-01 FACE, and the p...
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
Allantoin For Skin: A Comprehensive Guide
Ceramides For Skin: Everything You Need to Know
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
What Causes Crepey Skin & Can It Be Avoided Altoge...
Does Niacinamide Help With Acne & Scarring?
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
How OneSkin Developed the OS-01 Peptide
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging
Discover More
How Do Our Products Work Together?
The Connection Between Mental Health, Age Percepti...
MolClock: Using Epigenetics to Measure The Biologi...
How OS-01 BODY Pauses Biological Aging For Overall...
Biohacking Healthy Aging: The Organs of Longevity
5 Reasons Why Zinc Oxide Is Our Preferred UV Filte...
6 Common In-Office Skin Treatments to Complement y...
What is Microneedling & Are There Alternatives?
How to Protect Against and Reverse Collagen Loss
Why Your Neck, Décolletage, and Hands Need Extra C...
What's the Connection Between Dehydration and Dry ...
How to Tighten Facial Skin Without Surgery
Exploring Alternatives to Botox
Best Practices for Moisturizing After Exfoliating
Recognizing Signs of Over-Exfoliated Skin
Healing Over-Exfoliated Skin: How to Treat Over-Ex...
OS-01 BODY SPF and OS-01 BODY: Even Better Togethe...
Introducing OS-01 BODY SPF: Triple power protectio...
Is Talc Bad for Skin? 7 Things You Need to Know
How Do We Know the OS-01 Peptide is Safe?
What Is Lanolin and Is It Bad for Your Skin?
Non-Comedogenic vs Comedogenic Skin Care Products
Mineral Oil: Facts, Myths, and Effects on Skin
The Problem with Paraffin for Skin
Petrolatum: Is it Safe or Harmful for Your Skin?
How Much Sunscreen to Apply
What Do Antioxidants Do For Skin and Why Should Yo...
Making Sense of SPFs: What’s the Difference Betwee...
How to Relieve Itchy Skin: Tips for Soothing Skin ...
What is The Difference Between UVA and UVB Rays?
Decoding the Connections Between Intrinsic & Extri...
Causes of Skin Itching: Understanding the Reasons ...
How to Protect Your Skin from UVA and UVB Rays
Morning vs. Night Exfoliation: Determining the Bes...
How to Tell if Acne is Hormonal or Bacterial?
How to Know if Your Skin Barrier is Damaged
Tips for Managing Hormonal Breakouts
Understanding Hormonal Acne and Its Triggers
How to Repair & Restore Your Skin Barrier
How To Get Rid of Crepey Skin: 7 Solutions
When to Apply Sunscreen: Before or After Moisturiz...
How Alcohol Impacts Your Skin’s Health
The Effects of Alcohol on Your Skin's Aging Proces...
OS-01 FACE: Clinically Validated to Support Your S...
Can Alcohol Cause Breakouts?
The Proof is in the Peptide: 12-Week Clinical Stud...
Why Is My Neck Aging So Fast?
6 Factors That Contribute to Slow Skin Healing
6 Tips and Tricks for a Youthful Neck
Addressing the Need for Indoor Sun Protection
The Science of Sunburns: How to Treat and Prevent ...
Get to Know OneSkin’s Topical Supplements:
OS-01 F...
OS-01 F...
Can Air Quality Affect Skin? Exploring the Impact ...
Understanding the Relationship Between Sleep and U...
Exploring the Effects of Quality Sleep on Your Ski...
How to Improve Gut Microbiome
Exploring Caloric Restriction and Its Effects on A...
What’s the Connection Between Quality Sleep and Lo...
Unlocking the Skin Benefits of Intermittent Fastin...
Why Exercise is a Game-Changer for Longevity
The Microbiome Diet and Its Effects on Skin
Cold Exposure: Hype or Longevity Boosting?
Eat Better, Live Longer: Top Foods for Longevity
How to Protect Your Skin from Everyday Environment...
How Does Sunscreen Work? How Long Does it Last?
Pressing the Pause Button on Aging Skin: OS-01 BOD...
How to Brighten Eyes and Under-Eyes
Lip Balm Ingredients: What to Look for and What to...
Exploring Blue Zones: How Can We Optimize Our Heal...
Nurturing Your Lips: How to Keep Them Moisturized ...
Uncovering the 9 Causes of Dry Lips: Why Do Lips G...
How to Travel with Skin Care Products
Why is my Skin Peeling on My Face?
The Importance of Sunscreen: Why Should You Wear I...
Lip Sunscreen: Do Lips Need SPF Protection?
The Science of Gratitude
Removing Sunscreen: Tips for Clean and Healthy Ski...
Skin Explained: Is Skin An Organ?
UV Light and Skin: Effects and Protection Strategi...
Understanding The Epidermis: Functions, Compositio...
Diving into Dermis: Functions and Significance
Unlocking the Science of Wrinkles: Causes, Formati...
Why Skin Barrier is Important
Ingredient Spotlight: Bentonite Uses, Benefits, & ...
Hypodermis: Exploring Its Vital Functions
The EU is Limiting Retinol in Skincare: Here’s Eve...
Why You Should Use OS-01 FACE & OS-01 SHIELD Toget...
Age Gracefully: How to Manage Neck Wrinkles and Ac...
Discover Why Our New SPF Outperforms the Rest
How to Preserve Your Feet: 5 Strategies for Wrinkl...
Hands and Dermal Elasticity: Understanding and Man...
The Lip Lineage: Exploring the Why Behind Wrinkled...
How to Address Stomach Wrinkles For Smoother Skin
A Scientific Approach to Addressing Wrinkly Skin o...
What is Skin Cycling? Understanding, Embracing, an...
How to Skin Cycle: A Guide to Optimize Your Skin C...
Do You Know What Clinical Claims Really Mean?
What is Tinted Sunscreen?
2 Types of Wrinkles and Tips for Treating Them
Understanding Marionette Lines: Causes and Prevent...
How to Help Your Skin Act Younger
The Science of Sunscreen: Understanding the Optima...
Better Elasticity, More Firmness: Discover OS-01 E...
Symptoms and Causes of Melasma on Face
Navigating Anti-Aging Skincare: The industry, the ...
How to Prevent Skin Aging Before It Starts
A Comprehensive Guide to Understanding the Differe...
How to Strengthen Your Skin: A Guide to Thicker, H...
An In-Depth Look at Glycerin: What is it and What ...
Exploring the Benefits of Glycerin for Skin Health
Exploring the Difference Between Hydrating and Moi...
3 Natural Ways to Keep Your Skin Hydrated and Glow...
How To Create A Hydrating Skin Care Routine For Dr...
Senotherapeutics, Senolytics, and Senomorphics -- ...
Cleansing 101: How to Wash Your Face the Right Way...
Scientific Breakthrough: OneSkin’s scientists show...
Dry Skin 101: How To Identify This Skin Type
How OS-01 Can Help Your Collagen Levels As You Age...
Developing a Skin Care Routine for Normal Skin: 4 ...
What is Normal Skin & Do I Have This Skin Type?
A Step-by-Step Guide to Creating the Perfect Skin ...
Understanding Oily Skin: Causes & Characteristics
7 Keys to Understanding Menopause and Skin Changes
Is This The Root Cause of Aging?
UV Damage Increases Cellular Senescence. Here's Ho...
Our Research Has Been Published in npj Aging
How To Reduce Hyperpigmentation by Targeting Cellu...
4 Steps to Crafting the Perfect Skin Care Routine ...
A Comprehensive Guide to Understanding and Managin...
An In-Depth Look At The Benefits Of Moringa Oil Fo...
How to Tighten the Skin Under Your Eyes
7 Causes For Crepey Skin Under Eyes
101 Guide To Restoring Dry Skin Around The Eyes
How is OS-01 EYE different from OS-01 FACE?
How to Remove Lingering Dead Skin Cells On the Fac...
Safe Beauty, Validated: Why OneSkin trusts SkinSAF...
Hallmarks of Aging
What is Sensitive Skin?
3 Skin Tightening Ingredients To Help Boost Skin H...
How OS-01 Works on Mature Skin
Is Fragrance Bad for Your Skin?
Target Cellular Senescence with the Highest Concen...
Can a Plant-Based Diet Really Increase Your Health...
Eye Skin Ages Faster: Here’s How OS-01 Can Help
Gut Health and Skin: How Are They Connected?
The Science Behind Why The Skin Around the Eyes Ag...
How OS-01 EYE Supports the Ultra-Thin Skin Around ...
How Do You Know When to Stop Using Retinol?
How To Heal Skin From Picking Your Face Too Much
Collagen And Elastin: What Role Do They Play In Sk...
Why We Want Skin To Be More, Not Less
More Than Skin Deep: How Physical Touch Predicts L...
What is Skin Inflammation? What Causes it?
How to Reverse (or Prevent) Aging Skin
Yes, You Need Sunscreen During Winter
Can You Use Hyaluronic Acid with Retinol?
Exploring the skin’s purpose in whole-body health
Stressed Skin: 4 Stress Effects on the Skin
What Does Hyaluronic Acid Do For Your Skin?
Good Genes vs. Good Habits: Which Impacts Your Lon...
What is the Best Skin Care Regimen for Aging Skin?
What happens to skin as a person ages?
What Causes Dark Circles Under and Around Your Eye...
Invasive vs. Non-Invasive Skincare: The pros and c...
6 Benefits of Jojoba Oil
What are the Benefits of Sulforaphane?
What is Sustainable Packaging for Cosmetic Product...
7 Benefits of Andiroba Oil For Skin
What Are The Causes Of Dry, Flaky Skin On Your Fac...
PREP enhances the effects of OS-01 FACE, and the p...
This is the Data to Look For When Choosing Skin Ca...
Why cellular senescence is more than just one of t...
Allantoin For Skin: A Comprehensive Guide
Ceramides For Skin: Everything You Need to Know
A Simplified Guide To The Different Skin Texture T...
How OS-01 Works With Different Skin Types
How To Smooth Skin Texture On The Face: 4 Expert T...
What Causes Crepey Skin & Can It Be Avoided Altoge...
Does Niacinamide Help With Acne & Scarring?
Skin Microbiome: What It Is, Why it’s Important, A...
What Foods Cause Acne and Which Fight Against It?
The 101 Guide To Understanding Acne-Prone Skin
The Top 4 Prickly Pear Benefits for Skin
What Is Exfoliation & Is It A Necessary Measure Fo...
OneSkin Notable Mention: Dave Asprey's The Human U...
How to Incorporate OneSkin’s OS-01 Topical Supplem...
Clean Beauty: What “clean” really means and why “s...
Retinol 101: Debunking Retinol as the Gold Standar...
Menopause & Skin: What you need to know
Take an Inside Look into Our Cutting-Edge R&D Plat...
101 Guide On The Benefits Of Cleansing Your Face
How OneSkin Developed the OS-01 Peptide
Cleanser Vs. Face Wash: Which Should I Reach For?
Five Common Skin Problems Experienced in Perimenop...
Collagen For Menopause: Why Is It Necessary For He...
Get to Know OneSkin’s Topical Supplements:
...OS-
The Top 3 Benefits of Peptides for Skin
How to Use Peptides In Your Skincare Regimen to Op...
Peptides vs Retinol: Is One Better For Increasing ...
What Is Causing the Uneven Skin Tone On Your Body?
How To Boost Skin Moisture For Your Entire Body Fr...
Three Ways To Extend Your Skinspan Starting With Y...
What Are Free Radicals and How Do They Impact Skin...
The Top 6 Best Antioxidants For Skin Health and Lo...
What are Zombie Cells & How Can We Remove Them?
SKIN CARE IS HEALTH CARE: WHY EXTENDING YOUR SKINS...
How chronic stress makes you age faster
What is Epidermal Thickness & Why Does it Matter?
Cell Turnover & Why It Slows As We Age
OneSkin Notable Mention: OneSkin Featured In Tony ...
101 Guide To Skin Tightening + 7 Noninvasive Metho...
Tight Feeling Skin: 3 Reasons Why
How to Reduce Skin Inflammation & Redness
Niacinamide Vs Retinol: How Do They Compare?
Why Is Nutrient Absorption Key To Better Skin Heal...
OneSkin Notable Mention: LifeSpan Episode 6 | The ...
The Top 10 Best Foods for Skin Repair
Are There Dangers of Retinol Cream Use?
What is Skin Elasticity & How Can You Improve It?
A Complete Guide to the 4 Stages of Wound Healing
4 Foods To Avoid During Wound Healing & Why
Celebrating Black History Month: A Discussion With...
What is the Function of Skin as a Protective Barri...
Representation of the Black Community in Skin Care...
Our Story: Learn more about the history of OneSkin...
What Is Senescence & Its Relationship To Aging?
Winter Skincare - How To Prevent Dry Skin this Sea...
Special Announcement: OneSkin to Donate 1% of Sale...
Biological Age: What is Biological Age, Why Does i...
What your skincare routine is missing (Hint. It’s ...
What is a peptide?
Peptides: the first piece of th...
Peptides: the first piece of th...
Health Is The New Wealth
The Correlation Between Sleep and Skin: Why It Mat...
How Relationships, Community, & Social Interaction...
Calorie Restriction And Intermittent Fasting: Eati...
Healthspan: A New Way To Think About Aging