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Face

OS-01 Face Topical Supplement, 15ml

$40.00
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OS-01 FACE Topical Supplement, 15 mL (Limited Edition) 


While supplies last


The first skin longevity treatment that extends skin health on the molecular level to address aging from within. Formulated for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.




  •  Developed by longevity scientists


  •  Safe and clean


  •  For all skin types


  •  Vegan & Cruelty-Free


  • Flagrance free Fragrance-Free

“By preventing senescent cells from releasing pro-aging factors, we can prevent healthy cells from becoming “zombies”–containing the spread of senescence and slowing down skin aging.” 3Science2

Alessandra Zonari, PhD
OneSkin Co-Founder & CSO 3Science2
OneSkin

OS-01 Peptide 3Science2

Our OS-01 formula targets aging at the cellular level, leaving skin nourished and resilient to daily stress 3Science2

Science Driven Innovation 3Science2

Utilizing advanced research to create effective skincare solutions. 3Science2

Inclusivity and Accessibility

Catering to a diverse range of skin types and needs.

Longevity and Sustainability

Focusing on long-term skin health and eco-friendly practices.

the 30-day one skin challenge

Instantly hydrated,deeply nourished skin 3Science2

93% agree their skin feels protected

87% agree skin looks visibly firmer

80% agree their skin appears to regenerate overnight

OUR APPROACH

Results that go beyond the lab 3Science2

7

Years of Research 3Science2

900

Peptides Screened

0

Patents & Publications

9000

Patents & Publications

OneSkin

Behind One Skin Longevity 3Science2

3Science2 As more senescent cells accumulate, your skin experiences accelerated skin aging, including visible signs like wrinkles, loss of elasticity and firmness, crepiness, and thinning.

  1. Possible Increase of Skin’s Epidermal Thickness
  2. Increase of Key Biomarkers Associated with Cell Proliferation and Collagen Production
  3. May promote cell proliferation and collagen production, which can promote firmer, more renewed skin.
  4. Retinol Increases a Key Marker Associated with Skin Aging. OS-01 FACE Does Not.

How to apply OS-01 FACE and add to your routine 3Science2

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  • Dispense 1-2 pumps of OS-01 FACE onto fingers
  • Gently massage into skin on the face, neck, and hands
  • Use 2 times daily

3Science2

How it works 3Science2

Powered by the OS-01 Senescence Peptide™

The only peptide scientifically proven to reverse skin aging at the cellular level 01,02,03 3Science2

Frequently asked questions 3Science2

OS-01 Face Topical Supplement, 15ml

4.7
Rated 4.7 out of 5 stars
Based on 5,564 reviews
Total 5 star reviews: 4.5k Total 4 star reviews: 736 Total 3 star reviews: 232 Total 2 star reviews: 65 Total 1 star reviews: 56
94%would recommend these products
5,564 reviews
  • JJ
    Jennifer J.
    Verified Buyer
    Reviewing
    Replacement OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    7 hours ago
    Real deal

    I love this moisturizer! I’ve been using it for almost a year now & it really works great. I’m in my 40s and suits my skin perfectly. Recommend this for your everyday face lotion .

  • JI
    John I.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    13 hours ago
    OS-01 face wash

    I've been using the OneSkin OS-01 Face Wash for over a year and love it. I appreciate that it is "pricey", but it’s gentle yet effective, cleansing without drying my skin is priceless. The gel texture feels refreshing, and it leaves my skin smooth, clear, and prepped for the rest of my routine. Perfect for sensitive skin and a great complement to anti-aging care. JMI - 4-23-2025

  • M
    Michelle
    Verified Reviewer
    Reviewing
    OS-01 FACE Topical Supplement
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    THE BEST product I have ever used

    I have never written a review for a product, ever! One night when I had insomnia I was listening to a podcast and I heard one of the founder’s of OneSkin being interviewed. She mentioned that One Skin is endorsed by the eczema association. I have sensitive skin and eczema so I decided to give it a try. I have since bought every product in the line. I have recommended it to countless people and the other night we went out to dinner with friends . My friend text me after dinner and said “ I meant to ask you what you are using on your face. Is it some magical facial I should know about?. My old hands look younger and my skin is glowing. I can’t stop talking about these products.

    As I said , I have never written a review for anything . I highly recommend everything that One Skin has to offer.

  • RG
    Robby G.
    Verified Buyer
    Reviewing
    OS-01 FACE Refill Pouch
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Amazing!

    Great product, feels good, looks good and makes my routine so easy, I’m a man and I can say it’s great for all skin types. Highly recommend

  • VJ
    Vianey J.
    Verified Buyer
    Reviewing
    OS-01 FACE Topical Supplement Refill
    I recommend this product
    Rated 5 out of 5 stars
    Yesterday
    Easy, practical and green-friendly!

    Very pleased with this product and the practical replacement. I also appreciate that it’s green-friendly!

All Ingredients

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide.

Citations

01 Based on data from clinical studies and/or lab studies conducted on human skin samples, 3D skin models, and skin cells in the OneSkin lab. Explore more at oneskin.co/claims
02 Zonari, A., et al. npj Aging, 2023 03https://www.fda.gov/news-events/press-announcements/fda-advances-new-proposed-regulation-make-sure-sunscreens-are-safe-and-effective 04 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651070/ 05 https://academic.oup.com/bbb/article/72/12/3211/5941013 06 https://pubmed.ncbi.nlm.nih.gov/32522955/ 07 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8068194/ `https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583886

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